Zobrazeno 1 - 10
of 335
pro vyhledávání: '"Philip W, Wertz"'
Autor:
Philip W. Wertz, Sarah de Szalay
Publikováno v:
Antibiotics, Vol 9, Iss 4, p 159 (2020)
This special issue intends to review and update our understanding of the antimicrobial defense mechanisms of the skin and oral cavity. These two environments are quite different in terms of water, pH, and nutrient availability, but have some common a
Externí odkaz:
https://doaj.org/article/40a7896c5fe7440da20a2ed5a020c8a3
Autor:
Philip W. Wertz
Publikováno v:
Journal of Lipids, Vol 2018 (2018)
The primary purpose of the epidermis of terrestrial vertebrates is to produce the stratum corneum, which serves as the interface between the organism and the environment. As such, the stratum corneum provides a permeability barrier which both limits
Externí odkaz:
https://doaj.org/article/adc7e0ee8e2d4e128a8f974f83b93899
Publikováno v:
Journal of Cosmetic Dermatology. 21:3022-3030
Scope Two experiments were performed to test the effects of rich tomato extract (Golden Tomato Extract, GTE) on human skin. In one experiment, the effects of this extract on gene expression in cultured human dermal fibroblasts were examined. In a sec
Autor:
Leslie A. Mehalick, Christopher Poulsen, Carol L. Fischer, Emily A. Lanzel, Amber M. Bates, Katherine S. Walters, Joseph E. Cavanaugh, Janet M. Guthmiller, Georgia K. Johnson, Philip W. Wertz, Kim A. Brogden
Publikováno v:
Data in Brief, Vol 5, Iss C, Pp 285-291 (2015)
Long-chain bases, found in the oral cavity, have potent antimicrobial activity against oral pathogens. In an article associated with this dataset, Poulson and colleagues determined the cytotoxicities of long-chain bases (sphingosine, dihydrosphingosi
Externí odkaz:
https://doaj.org/article/adbf817f52084c56b00b47a718e54612
Autor:
Carol L. Fischer, Philip W. Wertz
Publikováno v:
Skin Microbiome Handbook
Autor:
Sarah de Szalay, Philip W. Wertz
Publikováno v:
International Journal of Molecular Sciences. 24:3145
The skin is the largest organ of the body and consists of an epidermis, dermis and subcutaneous adipose tissue. The skin surface area is often stated to be about 1.8 to 2 m2 and represents our interface with the environment; however, when one conside
Publikováno v:
Journal of Lipid Research, Vol 49, Iss 1, Pp 4-11 (2008)
The skin surface represents our interface with the external environment, and as such, is our first line of defense against microbial colonization and infection. Lipids at the skin surface are thought to underlie at least part of an antimicrobial barr
Externí odkaz:
https://doaj.org/article/328f067b1bea4c02a06b9918609c085c
Autor:
Philip W. Wertz
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 9383, p 9383 (2021)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
This is an attempt to make readers of the second edition of International Journal of Molecular Sciences Special Issue on the Barrier Function of Skin and Oral Mucosa aware of the content of the first edition on this same topic [...]
Autor:
Philip W. Wertz
Publikováno v:
Skin pharmacology and physiology. 34(1)
Cornified cells of the stratum corneum have a monolayer of an unusual lipid covalently attached to the outer surface. This is referred to as the corneocyte lipid envelope (CLE). It consists of a monolayer of ω-hydroxyceramides covalently attached to
Autor:
Philip W. Wertz
Publikováno v:
Skin Pharmacology and Physiology. 31:262-268
In the mid-1950s and 1960s, transmission electron microscopes became widely available, leading to many studies of the ultrastructure of various tissues including the epidermis. Most of these studies involved tissue fixation with formaldehyde and post