Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Philip Villanueva"'
Autor:
Daniel Hoer, Hugh A. Barton, Alicia Paini, Michael Bartels, Brandall Ingle, Jeanne Domoradzki, Jeffrey Fisher, Michelle Embry, Philip Villanueva, David Miller, James Nguyen, Qiang Zhang, Stephen W. Edwards, Yu-Mei Tan
Publikováno v:
Toxicology and Applied Pharmacology. 440:115922
Although external concentrations are more readily quantified and often used as the metric for regulating and mitigating exposures to environmental chemicals, the toxicological response to an environmental chemical is more directly related to its inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bec38cae6a8156f3a2932f96010da84
https://doi.org/10.1016/j.taap.2022.115922
https://doi.org/10.1016/j.taap.2022.115922
Autor:
David J. Miller, James Nguyen, Harvey J. Clewell, Monique M. Perron, Rachel Brunner, Pankaj Gulati, Nicole Kleinstreuer, Rhian B. Cope, Anna Lowit, Alan R. Boobis, Jeffrey M. Minucci, Elizabeth Mendez, Jeffrey Dawson, Alicia Paini, Yu-Mei Tan, Kelly Lowe, Hua Qian, Philip Villanueva, Jeanne Y. Domoradzki, Michelle R. Embry, John F. Wambaugh, Katherine Phillips, Hugh A. Barton, Brandall Ingle, Tharacad S. Ramanarayanan, Fiona Sewell, Peter P. Egeghy
Publikováno v:
Regulatory Toxicology and Pharmacology. 127:105070
Top dose selection for repeated dose animal studies has generally focused on identification of apical endpoints, use of the limit dose, or determination of a maximum tolerated dose (MTD). The intention is to optimize the ability of toxicity tests per
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc3e1f46759dcebdc5d9d57a94c8fe97
https://doi.org/10.1016/j.yrtph.2021.105070
https://doi.org/10.1016/j.yrtph.2021.105070