Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Philip T. Palade"'
Autor:
Sanjay Awasthi, Ashly Hindle, Neha A. Sawant, Mathew George, Murali Vijayan, Sudhir Kshirsagar, Hallie Morton, Lloyd E. Bunquin, Philip T. Palade, J. Josh Lawrence, Hafiz Khan, Chhanda Bose, P. Hemachandra Reddy, Sharda P. Singh
Publikováno v:
Cells, Vol 10, Iss 11, p 3113 (2021)
The purpose of our study is to understand the role of the RALBP1 gene in oxidative stress (OS), mitochondrial dysfunction and cognition in Alzheimer’s disease (AD) pathogenesis. The RALPB1 gene encodes the 76 kDa protein RLIP76 (Rlip). Rlip functio
Externí odkaz:
https://doaj.org/article/e190e49133eb4f918fe34b7c91dd8f50
Autor:
Se-Ran Jun, Amrita Cheema, Chhanda Bose, Marjan Boerma, Philip T. Palade, Eugenia Carvalho, Sanjay Awasthi, Sharda P. Singh
Publikováno v:
Microorganisms, Vol 8, Iss 10, p 1500 (2020)
Dietary factors modulate interactions between the microbiome, metabolome, and immune system. Sulforaphane (SFN) exerts effects on aging, cancer prevention and reducing insulin resistance. This study investigated effects of SFN on the gut microbiome a
Externí odkaz:
https://doaj.org/article/05088a60266f4873bccc338f353f7b0b
Autor:
Chhanda Bose, Ashly Hindle, Jihyun Lee, Jonathan Kopel, Sahil Tonk, Philip T. Palade, Sharad S. Singhal, Sanjay Awasthi, Sharda P. Singh
Publikováno v:
Cancers; Volume 13; Issue 24; Pages: 6377
Cancers
Cancers, Vol 13, Iss 6377, p 6377 (2021)
Cancers
Cancers, Vol 13, Iss 6377, p 6377 (2021)
Simple Summary Epidemiological evidence suggests that breast cancer risk is lowered by Ω-3 and increased by Ω-6 polyunsaturated fatty acids (PUFAs). Paradoxically, the Ω-6 PUFA metabolite 4-hydroxynonenal (4-HNE) inhibits cancer cell growth. This
Autor:
Ashly Hindle, Chhanda Bose, Jihyun Lee, Philip T. Palade, Christopher J. Peterson, P. Hemachandra Reddy, Sanjay Awasthi, Sharda P. Singh
Publikováno v:
Cancers, Vol 14, Iss 527, p 527 (2022)
Cancers; Volume 14; Issue 3; Pages: 527
Cancers; Volume 14; Issue 3; Pages: 527
Rlip76 (Rlip) is a multifunctional membrane protein that facilitates the high metabolic rates of cancer cells through the efflux of toxic metabolites and other functions. Rlip inhibition or depletion results in broad-spectrum anti-cancer effects in v
Autor:
Brittney R, Garner, Amanda J, Stolarz, Daniel, Stuckey, Mustafa, Sarimollaoglu, Yunmeng, Liu, Philip T, Palade, Nancy J, Rusch, Shengyu, Mu
Publikováno v:
The Journal of Pharmacology and Experimental Therapeutics
Pharmacological openers of ATP-sensitive potassium (KATP) channels are effective antihypertensive agents, but off-target effects, including severe peripheral edema, limit their clinical usefulness. It is presumed that the arterial dilation induced by