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pro vyhledávání: '"Philip Sherratt"'
Autor:
Daniel Potenta, Arthur Roth, Lewis B. Kinter, Carl L. Alden, Thomas Singer, Charles R. Mahrt, Joseph J. DeGeorge, Andrew R. Kraynak, John Evans, Bruce A. Trela, Richard Perry, Ronny Fransson-Steen, Jochen Woicke, Rabih Slim, Susan E. Turnquist, Matt Liu, David Brewster, Sandra De Jonghe, Karyn Colman, Douglas A. Keller, Vanessa Bosmans, Oliver C. Turner, Mark A. Dominick, Sivert Bjurström, M. Vijayaraj Reddy, James R. Hailey, Richard D. Storer, Frank D. Sistare, James R. Myer, Marjolein van Heerden, Keith A. Soper, Philip Sherratt, Daniel Morton, James H. Stoltz, Joel Christensen, Dirk Mariën, Jean-Guy Bienvenu
Publikováno v:
Toxicologic pathology. 39(4)
Data collected from 182 marketed and nonmarketed pharmaceuticals demonstrate that there is little value gained in conducting a rat two-year carcinogenicity study for compounds that lack: (1) histopathologic risk factors for rat neoplasia in chronic t