Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Philip Seu"'
Publikováno v:
Liver Transplantation. 11:800-806
The recently identified acute-phase response antimicrobial peptide hepcidin has been postulated to maintain iron homeostasis by modulating iron absorption at both the intestinal and macrophage levels. Hepcidin has also been reported to be responsible
Publikováno v:
Liver Transplantation. 9:401-410
Very little is known about iron metabolism and the mediators of iron metabolism in liver subjected to cold storage before transplantation. Therefore, in this study, we investigated the effect of cold storage on iron homeostasis in the rat liver. When
Publikováno v:
Transplantation. 73:1252-1257
Background It has been shown that in situ split-liver transplantation (SLT) expands the cadaveric donor pool, decreases recipient waiting time, and decreases pretransplant morbidity. However, the technique as previously described requires a microvasc
Publikováno v:
Microbes and Infection. 4:351-359
Slc11a1 (solute carrier family 11 member 1) (formerly Nramp1) modulation of iron metabolism in macrophages plays an important role in early phase macrophage activation, and therefore host innate immunity. This review focuses on the role of Nramp1 in
Publikováno v:
Transplantation. 72:1853-1858
Background. Split-liver transplantation offers a unique opportunity to expand the existing donor pool. However, it has previously been stated that due to inadequate liver volume the advantages of split-liver transplantation would be lost when attempt
Autor:
Ana J. Coito, Ronald W. Busuttil, Jerzy W. Kupiec-Weglinski, Bibo Ke, Yuan Zhai, Philip Seu, Tao Wang, Birgit Sawitzki, Hirohisa Kato
Publikováno v:
Transplantation. :1690-1694
Background. Fas ligand (FasL) induces apoptosis of cells bearing Fas receptor, and may play a role in the acquisition of immune privilege. We have previously shown that adenovirus (Ad)-mediated FasL gene transfer significantly prolongs survival in a
Autor:
Melinda A. Maggard, Ronald W. Busuttil, Judith E. Brill, Jorge Vargas, Kim Swenson, John A. Goss, Martin G. Martin, Sue V. McDiarmid, Christopher R. Shackleton, Rick Harrison, Philip Seu, Marvin E. Ament
Publikováno v:
Annals of Surgery. 228:411-420
OBJECTIVE: To analyze a single center's 13-year experience with 569 pediatric orthotopic liver transplants for end-stage liver disease. SUMMARY BACKGROUND DATA: Despite advances in medical therapy, liver replacement continues to be the only definitiv
Autor:
Christopher R. Shackleton, Ronald W. Busuttil, John A. Donovan, SM Rudich, Milan Kinkhabwala, John A. Goss, David K. Imagawa, Judy Melinek, Hugo R. Rosen, Paul Martin, Philip Seu
Publikováno v:
Transplantation. 65:68-72
Background. We retrospectively reviewed 213 consecutive patients who received their first liver allograft between January 1 and December 31, 1993, in order to study the impact of ischemia/preservation/reperfusion injury (IPRI) on patient and graft ou
Autor:
Ronald W. Busuttil, Tao Wang, Fady M. Kaldas, Bibo Ke, Melinda A. Maggard, David K. Imagawa, Philip Seu
Publikováno v:
Transplantation. :149-155
Background. Pravastatin, a 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor, inhibits coronary transplant vasculopathy in the clinical setting. To further delineate the immune modulatory effect of this agent, it was tested in a rat cardiac t
Autor:
Kim M. Swenson, David K. Imagawa, Bibo Ke, Jay S. Markowitz, Tao Wang, Gerald S. Spear, Ronald W. Busuttil, Philip Seu, John A. Goss, Melinda A. Maggard
Publikováno v:
Transplantation. :155-160
Background. Fas ligand (FasL) induces apoptosis of cells bearing its receptor Fas, and has been shown to be important in T-cell development and regulation and in immune privilege. We hypothesized that FasL expression by renal allografts might provide