Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Philip Serwer"'
Autor:
James P. Chambers, Miranda Aldis, Julie A. Thomas, Cara B. Gonzales, Richard Allen White, Philip Serwer
Publikováno v:
Biophysica, Vol 4, Iss 2, Pp 195-206 (2024)
Past anti-bacterial use of bacteriophages (phage therapy) is already well reviewed as a potential therapeutic response to the emergence of multidrug-resistant, pathogenic bacteria. Phage therapy has been limited by the following. (1) The success rate
Externí odkaz:
https://doaj.org/article/673047e8805e4bbf8c9310378e4e47e5
Publikováno v:
Biophysica, Vol 3, Iss 4, Pp 558-568 (2023)
Phage characterization for research and therapy can involve newly isolated phages propagated in pathogenic bacteria. If so, characterization requires safety-managing the bacteria. In the current study, we adapt a common and inexpensive reagent, Prime
Externí odkaz:
https://doaj.org/article/fbe79eec49e54c4f815c3aee25fcb6a1
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 6, p 3479 (2024)
Amyloid-associated neurodegenerative diseases, including Alzheimer’s disease (AD), are characterized by the in-brain accumulation of β-sheet structured protein aggregates called amyloids. However, neither a disease model nor therapy is established
Externí odkaz:
https://doaj.org/article/b50e0274c90b4b82bae1eb7a0af37ad8
Autor:
Philip Serwer, Elena T. Wright
Publikováno v:
Biophysica, Vol 2, Iss 4, Pp 366-380 (2022)
Chemotherapy-inhibiting tumor cell evolution to drug-resistance is potentially suppressed by using a drug delivery vehicle (DDV) that has gating. Gating would be used to increase tumor-selectivity of delivery of DDV packaged drug. Tumor-selectivity i
Externí odkaz:
https://doaj.org/article/7b31c5e45dce4bcbb9b55ee39647fee1
Publikováno v:
Viruses, Vol 15, Iss 12, p 2409 (2023)
The following hypothesis proposes non-diffusive, environmental bacteriophage (phage) motion. (1) Some phage-hosting, motile bacteria undergo chemotaxis down ATP concentration gradients to escape lysis-inducing conditions, such as phage infection. (2)
Externí odkaz:
https://doaj.org/article/6b16f5e2443e46f6bd1bc252d5c87d62
Siphophage 0105phi7-2 of Bacillus thuringiensis: Novel Propagation, DNA, and Genome-Implied Assembly
Autor:
Samantha M. Roberts, Miranda Aldis, Elena T. Wright, Cara B. Gonzales, Zhao Lai, Susan T. Weintraub, Stephen C. Hardies, Philip Serwer
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 10, p 8941 (2023)
Diversity of phage propagation, physical properties, and assembly promotes the use of phages in ecological studies and biomedicine. However, observed phage diversity is incomplete. Bacillus thuringiensis siphophage, 0105phi-7-2, first described here,
Externí odkaz:
https://doaj.org/article/5ed1dffd2b4d4357aea5ec0396a9a49a
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-5 (2019)
Abstract Objective Our immediate objective is to determine whether infectivity of lytic podophage T3 has a relatively high persistence in the blood of a mouse, as suggested by previous data. Secondarily, we determine whether the T3 surface has change
Externí odkaz:
https://doaj.org/article/fae21524c97f4ae49deb317d1eeff5aa
Autor:
Philip Serwer
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 14, p 7854 (2022)
The Special Issue “DNA Packaging Dynamics of Bacteriophages” is focused on an event that is among the physically simplest known events with biological character. Thus, phage DNA (and RNA) packaging is used as a relatively accessible model for phy
Externí odkaz:
https://doaj.org/article/a35d0c6b17c04723ad6701754ee73288
Publikováno v:
BMC Research Notes, Vol 11, Iss 1, Pp 1-5 (2018)
Abstract Objective Our immediate objective is to test the data-suggested possibility that in-agarose gel bacterial propagation causes gel fiber dislocation and alteration of cell distribution. We also test the further effect of lowering water activit
Externí odkaz:
https://doaj.org/article/5871f66181f34bf6b19ccd7575b20aa1
Autor:
Brenda González, Daoyi Li, Kunpeng Li, Elena T. Wright, Stephen C. Hardies, Julie A. Thomas, Philip Serwer, Wen Jiang
Publikováno v:
Viruses, Vol 13, Iss 10, p 2094 (2021)
Phage G is recognized as having a remarkably large genome and capsid size among isolated, propagated phages. Negative stain electron microscopy of the host–phage G interaction reveals tail sheaths that are contracted towards the distal tip and deco
Externí odkaz:
https://doaj.org/article/fd20da8ca4b64280b933e757ac8ef00f