3D-speckle-tracking echocardiography correlates with cardiovascular magnetic resonance imaging diagnosis of acute myocarditis – An observational study

Autor: Philip Roger Goody, Sebastian Zimmer, Can Öztürk, Angela Zimmer, Jens Kreuz, Marc Ulrich Becher, Alexander Isaak, Julian Luetkens, Atsushi Sugiura, Felix Jansen, Georg Nickenig, Christoph Hammerstingl, Vedat Tiyerili

Publikováno v: International Journal of Cardiology: Heart & Vasculature, Vol 41, Iss , Pp 101081- (2022)

Background: The diagnostic importance of three-dimensional (3D) speckle-tracking strain-imaging echocardiography in patients with acute myocarditis remains unclear. The aim of this study was to test the diagnostic performance of 3D-speckle-tracking e

Externí odkaz: https://doaj.org/article/87733a92b8f241b09fdb3f782bb534b3

NcRNAs in Vascular and Valvular Intercellular Communication

Autor: Benedikt Bartsch, Philip Roger Goody, Mohammed Rabiul Hosen, Denise Nehl, Neda Mohammadi, Andreas Zietzer, Philip Düsing, Alexander Pfeifer, Georg Nickenig, Felix Jansen

Publikováno v: Frontiers in Molecular Biosciences, Vol 8 (2021)

Non-coding RNAs have been shown to be important biomarkers and mediators of many different disease entities, including cardiovascular (CV) diseases like atherosclerosis, aneurysms, and valvulopathies. Growing evidence suggests a central role of ncRNA

Externí odkaz: https://doaj.org/article/3970af180b7a428b9fa75c53d17daea9

AIM2 Stimulation Impairs Reendothelialization and Promotes the Development of Atherosclerosis in Mice

Autor: Enzo Lüsebrink, Philip Roger Goody, Catharina Lahrmann, Anna Flender, Sven Thomas Niepmann, Andreas Zietzer, Christian Schulz, Steffen Massberg, Felix Jansen, Georg Nickenig, Sebastian Zimmer, Alexander Otto Krogmann

Publikováno v: Frontiers in Cardiovascular Medicine, Vol 7 (2020)

Background: Atherosclerosis has been shown to result from chronic inflammation caused by constitutive activation of the pattern recognition receptors (PRR), which are principle effectors of the innate immune system. PRR are present in the endosome or

Externí odkaz: https://doaj.org/article/8bfb08f49b7245cd9a80006f442e9e6b

The lncRNA MRPL20-AS1 is associated with severe OSAS and downregulated upon hypoxic injury of endothelial cells

Autor: Andreas, Zietzer, Nils, Breitrück, Philip, Düsing, Sabrina, Böhle, Jens Peter, Klussmann, Baravan, Al-Kassou, Philip Roger, Goody, Mohammed Rabiul, Hosen, Georg, Nickenig, Lisa, Nachtsheim, Sami, Shabli, Felix, Jansen, Stefanie, Jansen

Publikováno v: International Journal of Cardiology. 369:65-68

Obstructive sleep apnea syndrome (OSAS) is the most common sleep disorder in humans. Although OSAS is clearly related to arterial hypertension, coronary artery disease, and heart failure, it remains unknown through which pathomechanisms OSAS influenc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91b93ecbe93092f7f83ad0a71149a31c
https://doi.org/10.1016/j.ijcard.2022.08.035

Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles

Autor: Mohammed Rabiul Hosen, Philip Roger Goody, Andreas Zietzer, Xu Xiang, Sven Thomas Niepmann, Alexander Sedaghat, Vedat Tiyerili, Ramesh Chennupati, Joseph B. Moore, Reinier A. Boon, Shizuka Uchida, Jan-Malte Sinning, Sebastian Zimmer, Eicke Latz, Nikos Werner, Georg Nickenig, Felix Jansen

Publikováno v: Hosen, M R, Goody, P R, Zietzer, A, Xiang, X, Niepmann, S T, Sedaghat, A, Tiyerili, V, Chennupati, R, Moore, J B, Boon, R A, Uchida, S, Sinning, J-M, Zimmer, S, Latz, E, Werner, N, Nickenig, G & Jansen, F 2022, ' Circulating MicroRNA-122-5p Is Associated With a Lack of Improvement in Left Ventricular Function After Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles ', Circulation, vol. 146, no. 24, pp. 1836-1854 . https://doi.org/10.1161/CIRCULATIONAHA.122.060258
Hosen, M R, Goody, P R, Zietzer, A, Xiang, X, Niepmann, S T, Sedaghat, A, Tiyerili, V, Chennupati, R, Moore, J B, Boon, R A, Uchida, S, Sinning, J-M, Zimmer, S, Latz, E, Werner, N, Nickenig, G & Jansen, F 2022, ' Circulating MicroRNA-122-5p Is Associated with a Lack of Improvement in Left Ventricular Function after Transcatheter Aortic Valve Replacement and Regulates Viability of Cardiomyocytes Through Extracellular Vesicles ', Circulation, vol. 146, no. 24, pp. 1836-1854 . https://doi.org/10.1161/CIRCULATIONAHA.122.060258
Circulation, 146(24), 1836-1854. Lippincott Williams and Wilkins

Background: Transcatheter aortic valve replacement (TAVR) is a well-established treatment option for high- and intermediate-risk patients with severe symptomatic aortic valve stenosis. A majority of patients exhibit improvements in left ventricular e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ffa11ed46bcb97402d9900d0d17b189
https://pubmed.ncbi.nlm.nih.gov/35862223