Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Philip R.L. Parker"'
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3475-3483.e4 (2019)
Summary: Sensory perception arises from the integration of externally and internally driven representations of the world. Disrupted balance of these representations can lead to perceptual deficits and hallucinations. The serotonin-2A receptor (5-HT2A
Externí odkaz:
https://doaj.org/article/b6bed7b708564f92b755e068a5f19b12
Autor:
Philip R.L. Parker, Elliott T.T. Abe, Emmalyn S.P. Leonard, Dylan M. Martins, Cristopher M. Niell
Publikováno v:
Neuron. 110(23)
Visual input during natural behavior is highly dependent on movements of the eyes and head, but how information about eye and head position is integrated with visual processing during free movement is unknown, as visual physiology is generally perfor
Publikováno v:
Neural Development
Neural Development, Vol 15, Iss 1, Pp 1-20 (2020)
Neural Development, Vol 15, Iss 1, Pp 1-20 (2020)
Background Developing cortical neurons express a tightly choreographed sequence of cytoskeletal and transmembrane proteins to form and strengthen specific synaptic connections during circuit formation. Nectin-3 is a cell-adhesion molecule with previo
Publikováno v:
Trends Neurosci
Recent studies have demonstrated prominent and widespread movement-related signals in the brain of head-fixed mice, even in primary sensory areas. However, it is still unknown what role these signals play in sensory processing. Why are these sensory
Autor:
Arturo Alvarez-Buylla, Arnold R. Kriegstein, Miguel Turrero García, Emanuele Mazzola, Philip R.L. Parker, Luis C. Fuentealba, Constance L. Cepko, Corey C. Harwell, Caitlyn C. Gertz, Adrian Gonzalez-Cerrillo
Publikováno v:
Neuron, vol 87, iss 5
SummaryThe mammalian neocortex is composed of two major neuronal cell types with distinct origins: excitatory pyramidal neurons and inhibitory interneurons, generated in dorsal and ventral progenitor zones of the embryonic telencephalon, respectively
Publikováno v:
Neuron
Movement suppression in Parkinson's disease (PD) is thought to arise from increased efficacy of the indirect pathway basal ganglia circuit, relative to the direct pathway. However, the underlying pathophysiological mechanisms remain elusive. To exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4258de69dbccf0cfd0d4a85fca8064ca
https://europepmc.org/articles/PMC4760843/
https://europepmc.org/articles/PMC4760843/
Publikováno v:
Nature. 464(7288)
Neurons in the developing rodent cortex are generated from radial glial cells that function as neural stem cells. These epithelial cells line the cerebral ventricles and generate intermediate progenitor cells that migrate into the subventricular zone
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(31)
Gap junctions mediate metabolic and electrical interactions between some cells of the central nervous system. For many types of neurons, gap junction-mediated electrical coupling is most prevalent during early development, then decreases sharply with
Sonic Hedgehog Expression in Corticofugal Projection Neurons Directs Cortical Microcircuit Formation
Autor:
Ami Okada, Steven M. Gee, Susan K. McConnell, Corey C. Harwell, Philip R.L. Parker, Arnold R. Kriegstein, Anatol C. Kreitzer
Publikováno v:
Neuron. (6):1116-1126
SummaryThe precise connectivity of inputs and outputs is critical for cerebral cortex function; however, the cellular mechanisms that establish these connections are poorly understood. Here, we show that the secreted molecule Sonic Hedgehog (Shh) is