Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Philip R. McQuary"'
Autor:
Philip R. McQuary, Chen-Yu Liao, Jessica T. Chang, Caroline Kumsta, Xingyu She, Andrew Davis, Chu-Chiao Chu, Sara Gelino, Rafael L. Gomez-Amaro, Michael Petrascheck, Laurence M. Brill, Warren C. Ladiges, Brian K. Kennedy, Malene Hansen
Publikováno v:
Cell Reports, Vol 14, Iss 9, Pp 2059-2067 (2016)
Deficiency of S6 kinase (S6K) extends the lifespan of multiple species, but the underlying mechanisms are unclear. To discover potential effectors of S6K-mediated longevity, we performed a proteomics analysis of long-lived rsks-1/S6K C. elegans mutan
Externí odkaz:
https://doaj.org/article/29b2484ea09e4ed5ac62471d7032b3bc
Autor:
Orane Visvikis, Louis R. Lapierre, Chu-Chiao Chu, Malene Hansen, Binnan Ong, Jessica T. Chang, Sara Gelino, Philip R. McQuary, C. Daniel De Magalhaes Filho, Andrew Dillin, Andrew Davis, Javier E. Irazoqui
Publikováno v:
Nature Communications. 4
Autophagy is a cellular recycling process that has an important anti-aging role, but the underlying molecular mechanism is not well understood. The mammalian transcription factor EB (TFEB) was recently shown to regulate multiple genes in the autophag
Publikováno v:
Molecular cell. 35(5)
Summary The COP9 signalosome (CSN) is thought to maintain the stability of cullin-RING ubiquitin ligases (CRL) by limiting the autocatalytic destruction of substrate adapters such as F box proteins (FBPs). CAND1, a protein associated with unneddylate