Výsledky vyhledávání - "Philip R. Clingan"

Immune checkpoint inhibitor-induced myocarditis, myositis, myasthenia gravis and transaminitis: a case series and review

Autor: Derrick Ho Wai Siu, Robert Sean O'Neill, Carole A Harris, Justine Wang, Luke Ardolino, Teesha Downton, Matthew Tong, Jun Hee Hong, Venessa Chin, Philip R Clingan, Morteza Aghmesheh, Hussein Soudy

Publikováno v: Immunotherapy. 14(7)

Immune checkpoint inhibitors have been incorporated into the treatment of various malignancies. An increasing body of literature is reporting rare but potentially fatal adverse events associated with these agents. In this case series, the authors rep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d1a6da22ab564a829288e9dd5bbb16b
https://pubmed.ncbi.nlm.nih.gov/35321560

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Efficacy and safety of cosibelimab, an anti–PD-L1 antibody, in patients with metastatic cutaneous squamous cell carcinoma

Autor: Philip R. Clingan, Daniel Brungs, Susan Arnold, Jermaine Coward, Samuel J. Fourie, Dean Laurence Harris, Andrii Kurochkin, Rahul Ladwa, Niel Malan, Andrew Michael Mant, Margie McGrath, Vinay Sharma, Hong Shue, Andrea Tazbirkova, James Oliviero, Jayesh Desai

Publikováno v: Journal of Clinical Oncology. 40:9537-9537

9537 Background: Programmed death receptor-1 (PD-1)–blocking antibodies are approved as monotherapy treatment for patients (pts) with metastatic or locally advanced cutaneous squamous cell carcinoma (CSCC) who are not candidates for curative surger

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::eb8912432ffca296ed5c80fd611ed0dc
https://doi.org/10.1200/jco.2022.40.16_suppl.9537

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Concurrent end-phase boost high-dose radiation therapy for non-small-cell lung cancer with or without cisplatin chemotherapy*

Autor: Caroline S. Fox, F Abell, Catherine Clark, Philip R. Clingan, Peter Graham, P De Sousa, A Capp, Lois Browne, Matthew Links

Publikováno v: Australasian Radiology. 50:342-348

Summary The aim of this study was to audit the results of a high-dose, combined-modality prospective protocol for non-small-cell lung cancer in terms of survival, disease-specific survival and toxicity. One hundred and twenty-one patients with non-sm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85e3eb1778279e4d98d4d559c2e6f03d
https://doi.org/10.1111/j.1440-1673.2006.01597.x

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Comparative effectiveness of 5-fluorouracil with and without oxaliplatin in the treatment of colorectal cancer in clinical practice

Autor: Emma, Healey, Gillian E, Stillfried, Simon, Eckermann, James P, Dawber, Philip R, Clingan, Marie, Ranson

Publikováno v: Anticancer research. 33(3)

First-line chemotherapeutic treatment of colorectal cancer (CRC) typically comprises oral (capecitabine) or intravenous 5-fluorouracil (5-FU) plus leucovorin (LV), in combination with oxaliplatin (XELOX or FOLFOX, respectively), although debate exist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b69c1e03819fd3ec0a7a87ff91d8c885
https://pubmed.ncbi.nlm.nih.gov/23482781

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MAJOR UPPER GASTROINTESTINAL HAEMORRHAGE ASSOCIATED WITH HEPATIC ARTERIAL CHEMOPERFUSION

Autor: William Ross, Philip R. Clingan, David L. Morris

Publikováno v: ANZ Journal of Surgery. 66:816-819

Background: The present study reviews the nature of upper gastrointestinal complications of hepatic arterial chemoperfusion at a tertiary referral centre for the treatment of hepatic malignancy. Methods: The patients involved in the present study all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cda2afbdb55d67920f70e9f7d736717
https://doi.org/10.1111/j.1445-2197.1996.tb00756.x

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A phase 2 study of tasisulam sodium (LY573636 sodium) as second-line treatment for patients with unresectable or metastatic melanoma

Autor: John M, Kirkwood, Rene, Gonzalez, Douglas, Reintgen, Philip R, Clingan, Robert R, McWilliams, Dinesh P, de Alwis, Annamaria, Zimmermann, Michael P, Brown, Robert L, Ilaria, Michael J, Millward

Publikováno v: Cancer. 117(20)

Tasisulam sodium (hereafter, tasisulam) is a novel anticancer agent that induces apoptosis through the intrinsic pathway and has antiangiogenic activity in preclinical models. Tasisulam demonstrated activity across a broad range of tumors, including

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::bc0673f500f62629b83392907f1b6701
https://pubmed.ncbi.nlm.nih.gov/21456002

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A randomized trial of cimetidine with 5-fluorouracil and folinic acid in metastatic colorectal cancer

Autor: Kiran Phadke, Janet Legge, Warwick J. Adams, William Ross, David L. Morris, Jenny O'Baugh, Philip R. Clingan, Matthew Links

Publikováno v: European Journal of Surgical Oncology (EJSO). 21:523-525

Cimetidine has demonstrated a survival benefit in a randomized trial as adjuvant therapy for gastric cancer. We have demonstrated expression of histamine receptors on colon cancer cell lines and inhibition of their growth with cimetidine. Cimetidine

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86cfcc896e13f8d32ee94739f2283378
https://doi.org/10.1016/s0748-7983(95)97083-5

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Radiologically placed hepatic artery catheter allows selection of patients with high-volume liver metastases for regional chemotherapy

Autor: David L. Morris, Jing Zhao, Philip R. Clingan, Derek Glenn

Publikováno v: Australasian radiology. 42(3)

SUMMARY Regional chemotherapy has achieved high response rates in hepatic metastases from colorectal cancer and has been shown to improve survival significantly. The present paper reports the use of pre-operative regional therapy to establish marker

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb6c9ef9a68f12b991e25db4927a3094
https://pubmed.ncbi.nlm.nih.gov/9727242

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