Zobrazeno 1 - 10
of 687
pro vyhledávání: '"Philip R Taylor"'
Autor:
Havva Keskin, Shao-Ming Wang, Arash Etemadi, Jin-Hu Fan, Sanford M Dawsey, Christian C Abnet, You-Lin Qiao, Philip R Taylor
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0255322 (2021)
BackgroundColorectal cancer (CRC) is among the most common cancers in economically developed countries and developing world. While dietary factors are associated with risk of CRC in the West and urban China, little is known about risk or protective f
Externí odkaz:
https://doaj.org/article/0d58ac55354a41d3aca7f8ef4f7f08aa
Autor:
Aiysha Thompson, Luke C Davies, Chia-Te Liao, Diogo M da Fonseca, James S Griffiths, Robert Andrews, Adam V Jones, Mathew Clement, Gordon D Brown, Ian R Humphreys, Philip R Taylor, Selinda J Orr
Publikováno v:
PLoS Pathogens, Vol 15, Iss 6, p e1007850 (2019)
Invasive candidiasis, mainly caused by Candida albicans, is a serious healthcare problem with high mortality rates, particularly in immunocompromised patients. Innate immune cells express pathogen recognition receptors (PRRs) including C-type lectin-
Externí odkaz:
https://doaj.org/article/89cb1158055e4646aa716fa2f4f95566
Autor:
Yueh-An Lu, Tanya Smith, Sumukh Deshpande, Chia-Te Liao, Bnar Talabani, Irina Grigorieva, Anna Mason, Robert Andrews, Timothy Bowen, Philip R. Taylor, Donald Fraser
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract Postnatal kidney growth is substantial and involves expansion in kidney tubules without growth of new nephrons, which are the functional units of the kidney. Proliferation and differentiation pathways underpinning nephron elongation are not
Externí odkaz:
https://doaj.org/article/afadf3b23c18410db074eceb3fcd3a5c
Autor:
Fatao Liu, Nan Hu, Kewei Jiang, Huaitian Liu, Mingyi Wang, Ying Hu, Tongwu Zhang, Ho-Hsiang Wu, Howard Yang, Hao Weng, Ping Dong, Carol Giffen, Bin Zhu, Maxwell P. Lee, Christian C. Abnet, Philip R. Taylor, Yun Liu, Yingbin Liu, Alisa M. Goldstein
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background Gastric cancer (GC), a molecularly heterogeneous disease, is the third leading cause of cancer death worldwide. The majority of GC cases worldwide occur in East Asia, predominantly China. Mutational Signature Framework offers an e
Externí odkaz:
https://doaj.org/article/959218a62fb5456682653adbb47e9cf6
Autor:
Jake E Thistle, Baiyu Yang, Jessica L Petrick, Jin-Hu Fan, You-Lin Qiao, Christian C Abnet, Philip R Taylor, Katherine A McGlynn
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0203926 (2018)
BACKGROUND:Tooth loss has been reported to be associated with the risk of liver cancer in several prior studies in economically advantaged countries. Whether this relationship is also evident in economically disadvantaged populations is not known. ME
Externí odkaz:
https://doaj.org/article/dcc0b547f6df4380b3f6ba78784eee3d
Autor:
Jessica L Petrick, Roni T Falk, Paula L Hyland, Patrick Caron, Ruth M Pfeiffer, Shannon N Wood, Sanford M Dawsey, Christian C Abnet, Philip R Taylor, Chantal Guillemette, Liam J Murray, Lesley A Anderson, Michael B Cook
Publikováno v:
PLoS ONE, Vol 13, Iss 1, p e0190325 (2018)
Esophageal adenocarcinoma (EA) is characterized by a strong male predominance. Sex steroid hormones have been hypothesized to underlie this sex disparity, but no population-based study to date has examined this potential association.Using mass spectr
Externí odkaz:
https://doaj.org/article/325b80664a61472e931bba8927cd57d7
Autor:
Sarah N. Lauder, Victoria J Tyrrell, Keith Allen-Redpath, Maceler Aldrovandi, David Gray, Peter Collins, Simon A Jones, Philip R Taylor, Valerie O'Donnell
Publikováno v:
Wellcome Open Research, Vol 2 (2017)
Background. The myeloid enzyme 12/15-lipoxygenase (LOX), which generates bioactive oxidized lipids, has been implicated in numerous inflammatory diseases, with several studies demonstrating an improvement in pathology in mice lacking the enzyme. Howe
Externí odkaz:
https://doaj.org/article/f5090539914842ae958ac2f738de381f
Autor:
Brenda Krishnacoumar, Martin Stenzel, Hilal Garibagaoglu, Yasunori Omata, Rachel L. Sworn, Thea Hofmann, Natacha Ipseiz, Magdalena A. Czubala, Ulrike Steffen, Antonio Maccataio, Cornelia Stoll, Christina Böhm, Martin Herrmann, Stefan Uderhardt, Robert H. Jenkins, Philip R. Taylor, Anika Grüneboom, Mario M. Zaiss, Georg Schett, Gerhard Krönke, Carina Scholtysek
Publikováno v:
Bone Research, Vol 12, Iss 1, Pp 1-10 (2024)
Abstract Efficient cellular fusion of mononuclear precursors is the prerequisite for the generation of fully functional multinucleated bone-resorbing osteoclasts. However, the exact molecular factors and mechanisms controlling osteoclast fusion remai
Externí odkaz:
https://doaj.org/article/a3409e48ebd5446880ba7bab830dfe79
Autor:
Gabrielle Stack, Emma Jones, Morgan Marsden, Maria A Stacey, Robert J Snelgrove, Paul Lacaze, Laura C Jacques, Simone M Cuff, Richard J Stanton, Awen M Gallimore, Tracy Hussell, Gavin W G Wilkinson, Peter Ghazal, Philip R Taylor, Ian R Humphreys
Publikováno v:
PLoS Pathogens, Vol 11, Iss 2, p e1004641 (2015)
CD200 receptor (CD200R) negatively regulates peripheral and mucosal innate immune responses. Viruses, including herpesviruses, have acquired functional CD200 orthologs, implying that viral exploitation of this pathway is evolutionary advantageous. Ho
Externí odkaz:
https://doaj.org/article/e69f5ed2db144e32af2dee37e2b1a0ca
Autor:
Paula L Hyland, Nan Hu, Melissa Rotunno, Hua Su, Chaoyu Wang, Lemin Wang, Ruth M Pfeiffer, Barbara Gherman, Carol Giffen, Cathy Dykes, Sanford M Dawsey, Christian C Abnet, Kathryn M Johnson, Ruben D Acosta, Patrick E Young, Brooks D Cash, Philip R Taylor
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93219 (2014)
Barrett's esophagus (BE) is a metaplastic precursor lesion of esophageal adenocarcinoma (EA), the most rapidly increasing cancer in western societies. While the prevalence of BE is increasing, the vast majority of EA occurs in patients with undiagnos
Externí odkaz:
https://doaj.org/article/f815fea185d14e4597a99cdd0fae801e