Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Philip R Gafken"'
Autor:
Aude Chapuis, Lisa A Jones, Alex Chen, Elise C Wilcox, Chenwei Lin, Philip R Gafken, Roland K Strong, Stanley C Lee
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/6eb8da73e5144043a5ee8c9d694121ba
Publikováno v:
eLife, Vol 8 (2019)
DUX4 is a transcription factor whose misexpression in skeletal muscle causes facioscapulohumeral muscular dystrophy (FSHD). DUX4’s transcriptional activity has been extensively characterized, but the DUX4-induced proteome remains undescribed. Here,
Externí odkaz:
https://doaj.org/article/0ef1432bc86143f6b7218ee81a8d4607
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141850 (2015)
Membranes define cellular and organelle boundaries, a function that is critical to all living systems. Like other biomolecules, membrane lipids are dynamically maintained, but current methods are extremely limited for monitoring lipid dynamics in liv
Externí odkaz:
https://doaj.org/article/544becc0193d49299e7e33c8f41e11a1
Autor:
Jacob J. Kennedy, Jeffrey R. Whiteaker, Richard G. Ivey, Aura Burian, Shrabanti Chowdhury, Chia-Feng Tsai, Tao Liu, ChenWei Lin, Oscar D. Murillo, Rachel A. Lundeen, Lisa A. Jones, Philip R. Gafken, Gary Longton, Karin D. Rodland, Steven J. Skates, John Landua, Pei Wang, Michael T. Lewis, Amanda G. Paulovich
Publikováno v:
Analytical Chemistry. 94:9540-9547
Despite advances in proteomic technologies, clinical translation of plasma biomarkers remains low, partly due to a major bottleneck between the discovery of candidate biomarkers and costly clinical validation studies. Due to a dearth of multiplexable
Autor:
Lori I. Robins, Andrew Clark, Philip R. Gafken, Samina Alam, Janice Milici, Reem Hassan, Che‐Yen Wang, Jeffrey Williams, Craig Meyers
Publikováno v:
Journal of Medical Virology. 94:3386-3393
Medical instruments that are not autoclavable but may become contaminated with high-risk human papillomaviruses (HPVs) during use must be thoroughly disinfected to avoid the possibility of iatrogenic transmission of infection. There is an expectation
Autor:
Lori I. Robins, Erika K. Keim, Deborah B. Robins, John S. Edgar, John S. Meschke, Philip R. Gafken, Jeffrey F. Williams
Publikováno v:
ACS Omega, Vol 6, Iss 51, Pp 35593-35599 (2021)
ACS Omega
ACS Omega
Interleukin-6 (IL-6) has been implicated in the pathogenesis of inflammatory events including those seen with COVID-19 patients. Positive clinical responses to monoclonal antibodies directed against IL-6 receptors (IL-6Rs) suggest that interference w
Autor:
Samuel A. Ritmeester-Loy, Jonathan D Lautz, Yue Zhang-Wong, Joshua Gustafson, Ashley Wilson, Chenwei Lin, Philip R. Gafken, Michael C Jensen, Rimas Orentas, Stephen E.P. Smith
Cells rely on activity-dependent protein-protein interactions to convey biological signals, but the state-dependent interactome is notoriously cell-specific and undercharacterized1. In the case of chimeric antigen receptor (CAR) T cells containing a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::978b188437d9d443b4af34aa5116201b
https://doi.org/10.1101/2022.06.07.495180
https://doi.org/10.1101/2022.06.07.495180
Autor:
Oscar Murillo, Tao Liu, Rachel A. Lundeen, Richard G. Ivey, Chenwei Lin, Aura Burian, Amanda G. Paulovich, Pei Wang, John D. Landua, Shrabanti Chowdhury, Philip R. Gafken, Michael T. Lewis, Chia-Feng Tsai, Gary Longton, Jacob J. Kennedy, Steven J. Skates, Jeffrey R. Whiteaker, Karin D. Rodland, Lisa A. Jones
Despite advances in proteomic technologies, clinical translation of plasma biomarkers remains low, partly due to a major bottleneck between the discovery of candidate biomarkers and downstream costly clinical validation studies. Due to a dearth of mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8cae76699093a357b6bd1cea8e5859fa
https://doi.org/10.1101/2021.09.02.458791
https://doi.org/10.1101/2021.09.02.458791
Autor:
Jeffrey F. Williams, John Scott Meschke, Deborah Robins, Lori I. Robins, Scott Edgar, Philip R. Gafken, Erika K. Keim
Interleukin-6 (IL-6) has been implicated in the pathogenesis of acute inflammatory events in COVID-19 patients. We exposed IL-6 to hypochlorous acid (HOCl) in vitro at concentrations reported to develop in vivo. After HOCl treatment the cytokine fail
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6a55d64222ba63d580ef635c811eb7a
https://doi.org/10.33774/chemrxiv-2021-s68cw
https://doi.org/10.33774/chemrxiv-2021-s68cw
Autor:
Daphne R. Mattos, Jeffrey D. Serrill, Philip R. Gafken, Kerry L. McPhail, Walter K. Vogel, Jane E. Ishmael
Publikováno v:
Cancer Research. 82:3916-3916
Coibamide A is a cyclopeptide natural product with potent antiproliferative activity against cultured human cancer cells and subcutaneous U87-MG glioblastoma tumors in mice. We have recently determined that coibamide A binds to the Sec61 translocon c