Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Philip R, Streeter"'
Autor:
Swati Mishra, Philip R. Streeter
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Type 1 diabetes (T1D) occurs as a consequence of the autoimmune destruction of insulin-producing pancreatic beta (β) cells and commonly presents with insulin deficiency and unregulated glycemic control. Despite improvements in the medical m
Externí odkaz:
https://doaj.org/article/1627ff1d3166461d8569d6d56ca457dd
Autor:
Nicholas R. Smith, John R. Swain, Paige S. Davies, Alexandra C. Gallagher, Michael S. Parappilly, Catherine Z. Beach, Philip R. Streeter, Ian A. Williamson, Scott T. Magness, Melissa H. Wong
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 6, Iss 1, Pp 79-96 (2018)
Continual renewal of the intestinal epithelium is dependent on active- and slow-cycling stem cells that are confined to the crypt base. Tight regulation of these stem cell populations maintains homeostasis by balancing proliferation and differentiati
Externí odkaz:
https://doaj.org/article/fddeaf7b1f954bfe884f0a06244f9c05
Autor:
Kathryn F. Cogger, Ankit Sinha, Farida Sarangi, Emily C. McGaugh, Diane Saunders, Craig Dorrell, Salvador Mejia-Guerrero, Yasaman Aghazadeh, Jillian L. Rourke, Robert A. Screaton, Markus Grompe, Philip R. Streeter, Alvin C. Powers, Marcela Brissova, Thomas Kislinger, M. Cristina Nostro
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
Pancreatic progenitors (PPs) can be derived from human pluripotent stem cells in vitro but efficiency of differentiation varies, making it hard to sort for insulin-producing cells. Here, the authors use a proteomic approach to identify the secretory
Externí odkaz:
https://doaj.org/article/fd9272cedfac4963a9e8b1e7fd7c10ad
Autor:
Craig Dorrell, Jonathan Schug, Pamela S. Canaday, Holger A. Russ, Branden D. Tarlow, Maria T. Grompe, Tamara Horton, Matthias Hebrok, Philip R. Streeter, Klaus H. Kaestner, Markus Grompe
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Dysfunction or loss of insulin-secreting β cells in the pancreas is a hallmark of diabetes. Here, Dorrell et al.identify four subpopulations of β cells in humans, which differ in gene expression and insulin secretion kinetics, and the abundance of
Externí odkaz:
https://doaj.org/article/4a8e221047c74cf29f151b27d212cf85
Autor:
Feorillo H. Galivo, Craig Dorrell, Maria T. Grompe, YongPing Zhong, Philip R. Streeter, Markus Grompe
Publikováno v:
Stem Cell Research, Vol 15, Iss 1, Pp 172-181 (2015)
Novel cell surface-reactive monoclonal antibodies generated against extrahepatic biliary cells were developed for the isolation and characterization of different cell subsets from normal adult human gallbladder. Eleven antigenically distinct gallblad
Externí odkaz:
https://doaj.org/article/c5fcc531c6d54ebb82ac48625f1ae9be
Autor:
Swati Mishra, Philip R. Streeter
Publikováno v:
Methods in Molecular Biology ISBN: 9781071628065
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5194b9e3cc783865d5be93c68ffd36a2
https://doi.org/10.1007/978-1-0716-2807-2_12
https://doi.org/10.1007/978-1-0716-2807-2_12
Autor:
Swati, Mishra, Philip R, Streeter
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2592
Innovations in the field of amphiphilic block copolymers have led to the development of a series of attractive polymer-based drug and gene delivery micellar formulations. The amphiphilic block copolymers' low critical micelle concentration (CMC) resu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::57a398f45ad01a806cad9cb7b39c9ada
https://pubmed.ncbi.nlm.nih.gov/36507993
https://pubmed.ncbi.nlm.nih.gov/36507993
Autor:
Craig Dorrell, Branden Tarlow, Yuhan Wang, Pamela S. Canaday, Annelise Haft, Jonathan Schug, Philip R. Streeter, Milton J. Finegold, Lincoln T. Shenje, Klaus H. Kaestner, Markus Grompe
Publikováno v:
Stem Cell Research, Vol 13, Iss 2, Pp 275-283 (2014)
Pancreatic Lgr5 expression has been associated with organoid-forming epithelial progenitor populations but the identity of the organoid-initiating epithelial cell subpopulation has remained elusive. Injury causes the emergence of an Lgr5+ organoid-fo
Externí odkaz:
https://doaj.org/article/77bfdf5c318448cb9545b2a68586efeb
Autor:
Audrey V. Parent, Sudipta Ashe, Gopika G. Nair, Mei-Lan Li, Jessica Chavez, Jennifer S. Liu, Yongping Zhong, Philip R. Streeter, Matthias Hebrok
Publikováno v:
Stem cell reports, vol 17, iss 4
Cell replacement therapy using β cells derived from stem cells is a promising alternative to conventional diabetes treatment options. Although current differentiation methods produce glucose-responsive β cells, they can also yield populations of un
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b5ca91d826ea7b59b75ce37c464716
https://escholarship.org/uc/item/6rb2624r
https://escholarship.org/uc/item/6rb2624r
Autor:
Swati Mishra, Philip R. Streeter
Publikováno v:
Scientific reports. 12(1)
Type 1 diabetes (T1D) occurs as a consequence of the autoimmune destruction of insulin-producing pancreatic beta (β) cells and commonly presents with insulin deficiency and unregulated glycemic control. Despite improvements in the medical management
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffee08bf790b7289b979dc79d7fcb11d
https://pubmed.ncbi.nlm.nih.gov/36351917
https://pubmed.ncbi.nlm.nih.gov/36351917