Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Philip Palade"'
Autor:
Philip Palade, Mahendran Mahadevan
Publikováno v:
Heart and Mind, Vol 6, Iss 3, Pp 207-208 (2022)
Externí odkaz:
https://doaj.org/article/7f214c582fa14187b70761dd41d178d2
Autor:
Nancy J. Rusch, Daniel Stuckey, Amanda J. Stolarz, Shengyu Mu, Mustafa Sarimollaoglu, Brittney R. Garner, Philip Palade, Yunmeng Liu
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 376:40-50
Pharmacological openers of ATP-sensitive potassium (KATP) channels are effective antihypertensive agents, but off-target effects, including severe peripheral edema, limit their clinical usefulness. It is presumed that the arterial dilation induced by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5be050d96270c738d6c06f357dfdc795
https://doi.org/10.1124/jpet.120.000121
https://doi.org/10.1124/jpet.120.000121
Autor:
Chhanda Bose, Sahil Tonk, Santosh Chavali, Sanjay Awasthi, Kishore Bhende, Philip Palade, Meenakshi Darden, Ashly Hindle, Tejaswini P. Reddy, Sharda P. Singh, Sriman Swarup, Vijay S. Tonk, Aditya Rajan
Publikováno v:
The Southwest Respiratory and Critical Care Chronicles. 8:7-20
Background: Comparative genomic hybridization (CGH) microarrays are used forgenome-wide evaluation of copy number variations (CNV) of known prognostic significance;however, unannotated variants of uncertain significance (VUS) are frequently present.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6cdda0b23913a39f5826cd5b706018fa
https://doi.org/10.12746/swrccc.v8i33.627
https://doi.org/10.12746/swrccc.v8i33.627
Autor:
Sanjay Awasthi, J. Josh Lawrence, Neha Sawant, Lloyd E Bunquin, Ashley Hindle, Sudhir Kshirsagar, Hafiz M. R. Khan, Sharda P. Singh, Chhanda Bose, Mathew George, Philip Palade, Hallie Morton, Murali Vijayan, P. Hemachandra Reddy
The purpose of our study is to understand the role of the Ralbp1 gene in oxidative stress (OS), mitochondrial dysfunction and cognition in Alzheimer’s disease (AD) pathogenesis. The Ralbp1 gene encodes the 76 kDa protein Rlip (aka RLIP76). Previous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a42b30ccaa5eb8086166baa566715d7d
https://doi.org/10.1101/2021.09.20.461132
https://doi.org/10.1101/2021.09.20.461132
Autor:
Rakhshanda Layeequr Rahman, Jihyun Lee, Sharad S. Singhal, Sharda P. Singh, Hongzhi Li, Philip Palade, Chhanda Bose, Jonathan Kopel, Catherine Jones, Sanjay Awasthi, Yate-Ching Yuan, Ashly Hindle
Publikováno v:
Cancers, Vol 13, Iss 3329, p 3329 (2021)
Cancers
Volume 13
Issue 13
Cancers
Volume 13
Issue 13
Simple Summary Rlip knockout has been reported to prevent cancer in highly cancer-susceptible mice lacking p53, and Rlip knockdown kills many types of cancer cells. In humans, breast cancer shows diverse characteristics, including HER2-driven subtype
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0f228e073825644317a6fc060c3fa3b
https://www.mdpi.com/2072-6694/13/13/3329
https://www.mdpi.com/2072-6694/13/13/3329
Publikováno v:
The Southwest Respiratory and Critical Care Chronicles. 7:7-35
Despite clear evidence of increased oxidative stress in the blood and tissues of critically ill intensive care unit patients, consistent beneficial effects of many different antioxidants have not been observed, and antioxidant therapy has not yet tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13343a54c2e9f5277c1908be2299c96c
https://doi.org/10.12746/swrccc.v7i27.511
https://doi.org/10.12746/swrccc.v7i27.511
Autor:
Marjan Boerma, Jun Se-Ran, Sanjay Awasthi, Philip Palade, Sharda P. Singh, Chhanda Bose, Amrita K. Cheema
Background Dietary factors may modulate many complex interactions between the microbiome, metabolome, and immune system and can have an impact on the functional status of older adults. Sulforaphane (SFN), a natural compound and Nrf2-related activator
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac8fdb4d624fedda6b63a8d7172e2eae
https://doi.org/10.21203/rs.3.rs-43818/v1
https://doi.org/10.21203/rs.3.rs-43818/v1
Autor:
Sharad S. Singhal, David Berz, Chhanda Bose, Catherine Jones, Jihyun Lee, Philip Palade, Sanjay Awasthi, Sushma Yadav, Rakhshanda Layeequr Rahman, Shabnam Rehman, Ashly Hindle, Jyotsana Singhal, Naga K. S. Cheedella, Meenakshi Darden, Sharda P. Singh
Publikováno v:
Cancers
Volume 12
Issue 6
Cancers, Vol 12, Iss 1446, p 1446 (2020)
Volume 12
Issue 6
Cancers, Vol 12, Iss 1446, p 1446 (2020)
RLIP76 (RAL-binding protein-1, Rlip) is a stress-protective mercapturic-acid-pathway transporter protein that also plays a key role in regulating clathrin-dependent endocytosis as a Ral effector. Targeted inhibition or depletion of Rlip causes regres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb27662a1f68c22577886b919e9d6129
https://pubmed.ncbi.nlm.nih.gov/32498332
https://pubmed.ncbi.nlm.nih.gov/32498332
Autor:
Inês N Alves, Chhanda Bose, Elisabet Børsheim, Marjan Boerma, Eugenia Carvalho, Amrita K. Cheema, Sharda P Singh, Philip Palade, Se-Ran Jun, Preeti Singh, Sanjay Awasthi
Publikováno v:
Aging Cell
Scheme depicts hypothesized decreases of heart and SKM function during aging via ROS and partial reversal by SFN activation of Nrf2 that results in significant restoration of function of both types of muscle. A decline in heart and skeletal muscle fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9afbf352600f765270cb2f2f0cfdecc9
https://hdl.handle.net/10216/143563
https://hdl.handle.net/10216/143563
Autor:
Louise Torp Dalgaard, Elisabet Børsheim, Preeti Singh, Sanjay Awasthi, Marija Petkovic, Chanda Bose, Inês N Alves, Eugenia Carvalho, Sharda P Singh, Philip Palade, Ermelindo C. Leal
Publikováno v:
The Journal of Nutritional Biochemistry. 98:108817
Visible impairments in skin appearance, as well as a subtle decline in its functionality at the molecular level, are hallmarks of skin aging. Activation of the nuclear factor (erythroid-derived 2)-like 2 (Nrf2)-pathway, which is important in controll
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cb3b668d1a8d632232124b651f2379
https://doi.org/10.1016/j.jnutbio.2021.108817
https://doi.org/10.1016/j.jnutbio.2021.108817