Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Philip P. Sapienza"'
Autor:
Saura C. Sahu, Philip P. Sapienza, Thomas J. Flynn, M.W. O'Donnell, Chung S. Kim, Ivan A. Ross, Richard F. Newell, Paddy L. Wiesenfeld
Publikováno v:
Journal of Applied Toxicology. 28:703-709
Androstenedione, a naturally occurring steroid hormone, has been used to enhance athletic performance. Little is known, however, about its hepatotoxicity. Clone-9 cells, a non-transformed epithelial cell line that was originally isolated from normal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21f8aec041f922b65eceeb00dee5cb5a
https://doi.org/10.1002/jat.1325
https://doi.org/10.1002/jat.1325
Publikováno v:
Journal of AOAC INTERNATIONAL. 74:857-861
The homogeneity of test substances in a carrier (animal feed) is a critical factor In conducting long-term feeding studies in laboratory animals. A method for determining the adequate amount of mixing to achieve homogeneity by a mixer of the type des
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90aa825b919723cd02564c440c439ddc
https://doi.org/10.1093/jaoac/74.5.857
https://doi.org/10.1093/jaoac/74.5.857
Autor:
Leonard Friedman, Dennis W. Gaines, Vira L. Olivito, Curtis N. Barton, Philip P. Sapienza, G.J. Ikeda, Theodore C. Michel, M.W. O'Donnell
Publikováno v:
Advances in Swine in Biomedical Research ISBN: 9781461376996
The Yucatan miniature pig was introduced to FDA’s Beltsville Research Facility in the early 1980s. We were impressed by the docile, calm temperament of this strain of miniature pig. The existing strain of miniature pig at our facility was a cross b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e48ef790b5af36690e7147d9a4a5f960
https://doi.org/10.1007/978-1-4615-5885-9_10
https://doi.org/10.1007/978-1-4615-5885-9_10
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 31(4)
14 C-labelled cinnamic aldehyde (CNMA) was given as a single oral dose, or 24 hr after multiple oral administration of non-radioactive CNMA for 7 days at 24-hr intervals, to male Fischer 344 rats at dose levels of 5, 50 or 500 mg/kg body weight. Resi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eef13e661075d22e11d34fcbb5b47dd2
https://pubmed.ncbi.nlm.nih.gov/8477915
https://pubmed.ncbi.nlm.nih.gov/8477915
Publikováno v:
Journal of Applied Toxicology; May2004, Vol. 24 Issue 3, p177-181, 5p
Autor:
Thomas F.X. Collins, John J. Walsh, Marcy L. McGinnis, Lois E. Bragg, Philip P. Sapienza, G.J. Ikeda
Publikováno v:
Journal of Applied Toxicology. 2:307-314
Pregnant FDA-strain Osborne-Mendel rats were administered repeated doses of caffeine by oral intubation (gavage) and by administration in the drinking water (ad libitum sipping). When [1-methyl-14C]caffeine was administered at a dosage of 80 mg per k
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20635707e089fd2a39d688897a7fc139
https://doi.org/10.1002/jat.2550020609
https://doi.org/10.1002/jat.2550020609
Comparative tissue distribution and excretion of [1-14C]acrylamide in beagle dogs and miniature pigs
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. 25(11)
Male beagle dogs and miniature pigs were given acrylamide in the diet for 3–4 wk at a dosage of 1 mg/kg/day. They were then given [1-14C]acrylamide as a single oral dose of 1 mg/kg. The animals were killed 6 hr or 1, 2, 4 or 14 days after administr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb61c78c0a7daea83ba682163b3fdc1
https://pubmed.ncbi.nlm.nih.gov/3692391
https://pubmed.ncbi.nlm.nih.gov/3692391
Autor:
Sprando RL; Center for Food Safety and Applied Nutrition, United States Food and Drug Administration, Laurel, MD 20708, USA. rsprando@cfsan.fda.gov, Collins TF, Black TN, Olejnik N, Sapienza P, Ramos-Valle M, Ruggles DI
Publikováno v:
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association [Food Chem Toxicol] 2005 Apr; Vol. 43 (4), pp. 505-13. Date of Electronic Publication: 2005 Jan 20.