Zobrazeno 1 - 10
of 90
pro vyhledávání: '"Philip P. Connell"'
Autor:
Liam F. Spurr, Carlos A. Martinez, Rohan R. Katipally, Soumya C. Iyer, Sian A. Pugh, John A. Bridgewater, John N. Primrose, Enric Domingo, Timothy S. Maughan, Michael I. D’Angelica, Mark Talamonti, Mitchell C. Posner, Philip P. Connell, Ralph R. Weichselbaum, Sean P. Pitroda
Publikováno v:
npj Precision Oncology, Vol 6, Iss 1, Pp 1-7 (2022)
Abstract Personalized treatment approaches for patients with limited liver metastases from colorectal cancer are critically needed. By leveraging three large, independent cohorts of patients with colorectal liver metastases (n = 336), we found that a
Externí odkaz:
https://doaj.org/article/e959372b8763414ba78ff05df5b5708b
Autor:
Stanley I. Gutiontov, William Tyler Turchan, Liam F. Spurr, Sherin J. Rouhani, Carolina Soto Chervin, George Steinhardt, Angela M. Lager, Pankhuri Wanjari, Renuka Malik, Philip P. Connell, Steven J. Chmura, Aditya Juloori, Philip C. Hoffman, Mark K. Ferguson, Jessica S. Donington, Jyoti D. Patel, Everett E. Vokes, Ralph R. Weichselbaum, Christine M. Bestvina, Jeremy P. Segal, Sean P. Pitroda
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Immune checkpoint blockade (ICB) improves outcomes in non-small cell lung cancer (NSCLC) though most patients progress. There are limited data regarding molecular predictors of progression. In particular, there is controversy regarding the r
Externí odkaz:
https://doaj.org/article/82195ffa5c7b45b097938796d4698839
Autor:
Scott R. Floyd, Justus Adamson, Philip P. Connell, Ralph R. Weichselbaum, Christopher G. Willett
Publikováno v:
Holland‐Frei Cancer Medicine. :1-10
Autor:
Susan L. Cohn, Philip P. Connell, Yusuke Nakamura, Emma Wilkinson, Mark A. Applebaum, Ryan Miller, Jae-Hyun Park, Brian Budke, Helen R. Salwen, Marija Dobratic, Chanyoung Park, Alexandre Chlenski
MYCN/MYC expression in N-type and S-type neuroblastoma cell lines
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03019b2e4e013bb650ca3b7c2f1f466a
https://doi.org/10.1158/1535-7163.22507038.v1
https://doi.org/10.1158/1535-7163.22507038.v1
Autor:
Susan L. Cohn, Philip P. Connell, Yusuke Nakamura, Emma Wilkinson, Mark A. Applebaum, Ryan Miller, Jae-Hyun Park, Brian Budke, Helen R. Salwen, Marija Dobratic, Chanyoung Park, Alexandre Chlenski
Maternal embryonic leucine zipper kinase (MELK) activates pathways that mediate aggressive tumor growth and therapy resistance in many types of adult cancers. Pharmacologic and genomic inhibition of MELK impairs tumor growth and increases sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d4febb23c7b71f32373ae7d55f84061a
https://doi.org/10.1158/1535-7163.c.6538560.v1
https://doi.org/10.1158/1535-7163.c.6538560.v1
Autor:
Susan L. Cohn, Philip P. Connell, Yusuke Nakamura, Emma Wilkinson, Mark A. Applebaum, Ryan Miller, Jae-Hyun Park, Brian Budke, Helen R. Salwen, Marija Dobratic, Chanyoung Park, Alexandre Chlenski
pRPA32 expression in neuroblastoma cells treated with OTS167 and CPT.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c58ba688ff09dc1f2df1acdca3bfff2b
https://doi.org/10.1158/1535-7163.22507032
https://doi.org/10.1158/1535-7163.22507032
Autor:
Susan L. Cohn, Philip P. Connell, Yusuke Nakamura, Emma Wilkinson, Mark A. Applebaum, Ryan Miller, Jae-Hyun Park, Brian Budke, Helen R. Salwen, Marija Dobratic, Chanyoung Park, Alexandre Chlenski
MELK and EZH2 RNA expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::862a748e7b00f5b7ddeeccda910c3a1d
https://doi.org/10.1158/1535-7163.22507035.v1
https://doi.org/10.1158/1535-7163.22507035.v1
Purpose: Molecular-based cancer tests have been developed to augment the standard clinical and pathologic features used to tailor treatments to individual breast cancer patients. Homologous recombination (HR) repairs double-stranded DNA breaks and pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fcb7cb13f6db7a40f0ddf206e816c73
https://doi.org/10.1158/1078-0432.c.6526967.v1
https://doi.org/10.1158/1078-0432.c.6526967.v1
This file includes: (1) legends for Supplementary Figures S1-S8 and Tables S1-S5 and (2) Supplementary Figures S1-S8. Figure S1: Study flow chart for selection of breast cancer patients. Figure S2: Distributions of SCAN normalized gene expression dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154f8c88fa1f51e5bc5730bb20c98a66
https://doi.org/10.1158/1078-0432.22468490.v1
https://doi.org/10.1158/1078-0432.22468490.v1
Autor:
Philip P. Connell, Douglas K. Bishop, Alan P. Kozikowski, Ralph R. Weichselbaum, Michal Pawlowski, Megan Wu, Brian Budke, Hillary L. Logan, Jennifer M. Mason
PDF file - 403KB, Supplemental Figure 1. Quantifications of western blots. Supplemental Figure 2. Knockdown of RAD51 in PC3 does not protect cells from the toxicity of ionizing radiation. Supplemental Table 1. Quantifications of statistical significa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a223739e1eb3f6749cbadfa26475bef
https://doi.org/10.1158/0008-5472.22399215
https://doi.org/10.1158/0008-5472.22399215