Zobrazeno 1 - 10
of 37
pro vyhledávání: '"Philip P. Ahern"'
Autor:
Isabel Johnston, Lucas J. Osborn, Rachel L. Markley, Elizabeth A. McManus, Anagha Kadam, Karlee B. Schultz, Nagashreyaa Nagajothi, Philip P. Ahern, J. Mark Brown, Jan Claesen
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-10 (2021)
Abstract Aryl polyenes (APEs) are specialized polyunsaturated carboxylic acids that were identified in silico as the product of the most widespread family of bacterial biosynthetic gene clusters (BGCs). They are present in several Gram-negative host-
Externí odkaz:
https://doaj.org/article/fa1a661b9c6b49bfbb6551d03da69c3f
Autor:
Megan T. Zangara, András K. Ponti, Noah D. Miller, Morgan J. Engelhart, Philip P. Ahern, Naseer Sangwan, Christine McDonald
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Food additives are common components of processed foods consumed in a Western diet. In inflammatory bowel disease patients, some diets that exclude food additives improved clinical disease parameters, suggesting a link between food additives and dise
Externí odkaz:
https://doaj.org/article/0ff349858f3d4ef2bd3b8aaa87ca877a
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
The profound impact of the gut microbiome on host health has led to a revolution in biomedical research, motivating researchers from disparate fields to define the specific molecular mechanisms that mediate host-beneficial effects. The advent of geno
Externí odkaz:
https://doaj.org/article/bd7c4405c0d6403bbe12051989f3496a
Autor:
Thomas Krausgruber, Chris Schiering, Krista Adelmann, Oliver J. Harrison, Agnieszka Chomka, Claire Pearson, Philip P. Ahern, Matthew Shale, Mohamed Oukka, Fiona Powrie
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-12 (2016)
How transcription factor T-bet and Th17 cells contribute to colitis remains incompletely understood. Here the authors identify T-bet as a negative regulator of IL-23R pathway activation and show that T-bet deficient T cells drive colitogenic Th17 res
Externí odkaz:
https://doaj.org/article/7468206667654e0d9f30482bda325b7b
Data from Disruption of the Gut Microbiota Confers Cisplatin Resistance in Epithelial Ovarian Cancer
Autor:
Ofer Reizes, Chad M. Michener, J. Mark Brown, Roberto Vargas, Peter Rose, Jan Claesen, Philip P. Ahern, Adeline Hajjar, Mohammed Dwidar, Sumita Dutta, Zeneng Wang, Amy S. Joehlin-Price, Peter Bazeley, Naseer Sangwan, Justin D. Lathia, Defne Bayik, Zahraa Alali, Lexie Trestan, Surabhi Tewari, Chad Braley, Rashmi Bharti, Emily L. Esakov Rhoades, Laura M. Chambers
Epithelial ovarian cancer (EOC) is the leading cause of gynecologic cancer death. Despite initial responses to intervention, up to 80% of patient tumors recur and require additional treatment. Retrospective clinical analysis of patients with ovarian
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::741c6440b86066bbf734f4577226911a
https://doi.org/10.1158/0008-5472.c.6514286.v1
https://doi.org/10.1158/0008-5472.c.6514286.v1
Autor:
Ofer Reizes, Chad M. Michener, J. Mark Brown, Roberto Vargas, Peter Rose, Jan Claesen, Philip P. Ahern, Adeline Hajjar, Mohammed Dwidar, Sumita Dutta, Zeneng Wang, Amy S. Joehlin-Price, Peter Bazeley, Naseer Sangwan, Justin D. Lathia, Defne Bayik, Zahraa Alali, Lexie Trestan, Surabhi Tewari, Chad Braley, Rashmi Bharti, Emily L. Esakov Rhoades, Laura M. Chambers
Supplemental Figures and Tables supporting manuscript.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23eb9039ed34bb43aaa0b1f6ae15d626
https://doi.org/10.1158/0008-5472.22432976
https://doi.org/10.1158/0008-5472.22432976
Autor:
Lucas J. Osborn, Karlee Schultz, William Massey, Beckey DeLucia, Ibrahim Choucair, Venkateshwari Varadharajan, Rakhee Banerjee, Kevin Fung, Anthony J. Horak, Danny Orabi, Ina Nemet, Laura E. Nagy, Zeneng Wang, Daniela S. Allende, Belinda B. Willard, Naseer Sangwan, Adeline M. Hajjar, Christine McDonald, Philip P. Ahern, Stanley L. Hazen, J. Mark Brown, Jan Claesen
Publikováno v:
Proceedings of the National Academy of Sciences. 119
The molecular mechanisms by which dietary fruits and vegetables confer cardiometabolic benefits remain poorly understood. Historically, these beneficial properties have been attributed to the antioxidant activity of flavonoids. Here, we reveal that t
Autor:
Morgan J. Engelhart, Robert W. P. Glowacki, Jessica M. Till, Clifford V. Harding, Eric C. Martens, Philip P. Ahern
The gut microbiome and intestinal immune system are engaged in a dynamic interplay that provides myriad benefits to host health. However, the microbiome can also elicit damaging inflammatory responses, and thus establishing harmonious immune-microbio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::25596cda52378430074fa27ff5dd8cd5
https://doi.org/10.1101/2022.10.21.513251
https://doi.org/10.1101/2022.10.21.513251
Autor:
Nagashreyaa Nagajothi, Elizabeth A. McManus, Lucas J Osborn, Philip P. Ahern, Jan Claesen, Isabel Johnston, Anagha Kadam, Rachel L. Markley, Karlee B. Schultz, J. Mark Brown
Publikováno v:
npj Biofilms and Microbiomes, Vol 7, Iss 1, Pp 1-10 (2021)
NPJ Biofilms and Microbiomes
NPJ Biofilms and Microbiomes
Aryl polyenes (APEs) are specialized polyunsaturated carboxylic acids that were identified in silico as the product of the most widespread family of bacterial biosynthetic gene clusters (BGCs). They are present in several Gram-negative host-associate
Autor:
Laura M. Chambers, Emily L. Esakov Rhoades, Rashmi Bharti, Chad Braley, Surabhi Tewari, Lexie Trestan, Zahraa Alali, Defne Bayik, Justin D. Lathia, Naseer Sangwan, Peter Bazeley, Amy S. Joehlin-Price, Zeneng Wang, Sumita Dutta, Mohammed Dwidar, Adeline Hajjar, Philip P. Ahern, Jan Claesen, Peter Rose, Roberto Vargas, J. Mark Brown, Chad M. Michener, Ofer Reizes
Publikováno v:
Cancer Res
Epithelial ovarian cancer (EOC) is the leading cause of gynecologic cancer death. Despite initial responses to intervention, up to 80% of patient tumors recur and require additional treatment. Retrospective clinical analysis of patients with ovarian