Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Philip Olivares"'
Autor:
Svetlana A. Shestopal, Leonid A. Parunov, Philip Olivares, Haarin Chun, Mikhail V. Ovanesov, John R. Pettersson, Andrey G. Sarafanov
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 15, p 8134 (2022)
Single-chain variable fragments (scFv) are antigen-recognizing variable fragments of antibodies (FV) where both subunits (VL and VH) are connected via an artificial linker. One particular scFv, iKM33, directed against blood coagulation factor VIII (F
Externí odkaz:
https://doaj.org/article/026a20d758e149e5a1412c85d1c496da
Publikováno v:
eLife, Vol 9 (2020)
Diffusible small molecule microbial hormones drastically alter the expression profiles of antibiotics and other drugs in actinobacteria. For example, avenolide (a butenolide) regulates the production of avermectin, derivatives of which are used in th
Externí odkaz:
https://doaj.org/article/44862aa21247454387a6948f2bc4d2a2
Publikováno v:
Biotechnology Reports, Vol 6, Iss C, Pp 112-118 (2015)
Alkaline phytase isolated from pollen grains of Lilium longiflorum (LlALP) possesses unique catalytic and thermal stability properties that suggest it has the potential to be used as a feed supplement. However, substantial amounts of active enzymes a
Externí odkaz:
https://doaj.org/article/c396dbdb46cf4ab1a6101d6b9dfb0588
Publikováno v:
Biotechnology Reports, Vol 8, Iss C, p 160 (2015)
Externí odkaz:
https://doaj.org/article/874ba3f6257645d2af7aa38edb1d41e7
Autor:
Haarin Chun, James H. Kurasawa, Philip Olivares, Ekaterina S. Marakasova, Svetlana A. Shestopal, Gabriela U. Hassink, Elena Karnaukhova, Mary Migliorini, Juliet O. Obi, Ally K. Smith, Patrick L. Wintrode, Prasannavenkatesh Durai, Keunwan Park, Daniel Deredge, Dudley K. Strickland, Andrey G. Sarafanov
Publikováno v:
Journal of Thrombosis and Haemostasis. 20:2255-2269
Deficiency in blood coagulation factor VIII (FVIII) results in life-threating bleeding (hemophilia A) treated by infusions of FVIII concentrates. To improve disease treatment, FVIII has been modified to increase its plasma half-life, which requires u
Autor:
Andrey Sarafanov, Leonid Parunov, Philip Olivares, Svetlana Shestopal, John Pettersson, Haarin Chun, Mikhail Ovanesov
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 15; Pages: 8134
Single-chain variable fragments (scFv) are antigen-recognizing variable fragments of antibodies (FV) where both subunits (VL and VH) are connected via an artificial linker. One particular scFv, iKM33, directed against blood coagulation factor VIII (F
Characterization of protein unable to bind von Willebrand factor in recombinant factor VIII products
Autor:
Philip Olivares, John R Pettersson, Mikhail V Ovanesov, Stepan S Surov, Ekaterina S. Marakasova, Wells W. Wu, Rong-Fong Shen, Andrey G Sarafanov, Haarin Chun, Svetlana A Shestopal
Publikováno v:
Journal of thrombosis and haemostasis : JTHREFERENCES. 19(4)
Background Therapeutic products with coagulation factor VIII (FVIII) have a wide range of specific activities, implying presence of protein with altered structure. Previous studies showed that recombinant FVIII products (rFVIII) contain a fraction (F
Autor:
Mikhail V Ovanesov, John R Pettersson, Rong-Fong Shen, Timothy K Lee, Svetlana A Shestopal, Andrey G Sarafanov, Philip Olivares, Wells W. Wu, Haarin Chun, Stepan S Surov, Ekaterina S. Marakasova
Publikováno v:
Blood. 136:25-26
Introduction Therapeutic products with blood coagulation factor VIII (FVIII) have a wide range of protein contents per activity unit (or IU/mg, specific activity), available from previous studies (Lin et al, 2004; Butenas et al, 2009) and the prescri
Autor:
Svetlana A Shestopal, Andrey G Sarafanov, Ekaterina S. Marakasova, James H. Kurasawa, Haarin Chun, Elena Karnaukhova, Dudley K. Strickland, Nancy E. Hernandez, Philip Olivares, Gabriela U. Hassink
Publikováno v:
The Journal of Biological Chemistry
The low-density lipoprotein receptor (LDLR) family of receptors are cell-surface receptors that internalize numerous ligands and play crucial role in various processes, such as lipoprotein metabolism, hemostasis, fetal development, etc. Previously, r