Zobrazeno 1 - 10
of 41
pro vyhledávání: '"Philip Noël Suffys"'
Autor:
Agathe Jouet, Sofie Marijke Braet, Cyril Gaudin, Gaëlle Bisch, Sidra Vasconcellos, Rebecca Emmanuela Epaminondas Nicacio de Oliveira do Livramento, Yrneh Yadamis Prado Palacios, Amanda Brum Fontes, Norma Lucena, Patricia Rosa, Milton Moraes, Kevin La, Nelly Badalato, Esteban Lenoir, Alice Ferré, Marie Clément, Epco Hasker, Silahi Halifa Grillone, Wirdane Abdou, Aouladi Said, Younoussa Assoumani, Nissad Attoumani, Yannick Laurent, Emmanuelle Cambau, Bouke Catherine de Jong, Philip Noël Suffys, Philip Supply
Publikováno v:
EBioMedicine, Vol 93, Iss , Pp 104649- (2023)
Summary: Background: Expansion of antimicrobial resistance monitoring and epidemiological surveillance are key components of the WHO strategy towards zero leprosy. The inability to grow Mycobacterium leprae in vitro precludes routine phenotypic drug
Externí odkaz:
https://doaj.org/article/afa44bec300b4e1ca706ecb98b36b085
Autor:
Tiago Araujo Gomes, Tatiana Pereira da Silva, Edson Machado, Sidra Ezidio Gonçalves Vasconcelos, Bruno Siqueira Mietto, Daniela Ferreira de Faria Bertoluci, Patricia Sammarco Rosa, Roberta Olmo Pinheiro, Philip Noel Suffys, Letícia Miranda Santos Lery, Flavio Alves Lara
Publikováno v:
Pathogens, Vol 13, Iss 11, p 986 (2024)
Throughout Mycobacterium leprae’s (M. leprae) evolutionary trajectory, nearly half of its genome was converted into pseudogenes. Despite this drastic reduction in genetic content, the genome sequence identity among M. leprae isolates worldwide is r
Externí odkaz:
https://doaj.org/article/fc976f82b1ce4c03bdc105b60aa1e32e
Autor:
Emilyn Costa Conceição, Johannes Loubser, Arthur Emil dos Santos Guimarães, Abhinav Sharma, Liliana Kokusanilwa Rutaihwa, Anzaan Dippenaar, Richard Steiner Salvato, Ricardo José de Paula Souza e Guimarães, Maria Cristina da Silva Lourenço, Wandyra Araújo Barros, Ninarosa Calzavara Cardoso, Robin Mark Warren, Sebastien Gagneux, Beatriz Gilda Jegerhorn Grinsztejn, Philip Noel Suffys, Karla Valéria Batista Lima
Publikováno v:
Microorganisms, Vol 12, Iss 9, p 1817 (2024)
A previous study in Pará, Northern Brazil, described a strain of Mycobacterium tuberculosis with a unique genotype (SIT2517/T1) associated with multidrug-resistant tuberculosis (MDR-TB). To improve our understanding of MDR-TB transmission dynamics o
Externí odkaz:
https://doaj.org/article/7e101bd4fc424b4f819b4b18d4072f33
Autor:
Cecília Alvim Dutra, Raquel Lima de Figueiredo Teixeira, Márcia Quinhones Pires Lopes, Victória de Moraes Silva, Philip Noel Suffys, Ricardo de Souza Carvalho, Adriana Rezende Moreira, Adalberto Rezende Santos, Afrânio Lineu Kritski
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 917 (2024)
The human N-acetyltransferase 2 enzyme, encoded by the NAT2 gene, plays an important role in the metabolism of isoniazid, the main drug used to treat tuberculosis. The interindividual variation in the response of patients to drug treatment for tuberc
Externí odkaz:
https://doaj.org/article/a22db480bb9a4c4c94a98d4ed9d7223f
Autor:
Camila Lopes Romagnoli, Emilyn Costa Conceição, Edson Machado, Leonardo Bruno Paz Ferreira Barreto, Abhinav Sharma, Natalia Maria Silva, Lucas Evangelista Marques, Maria Aparecida Juliano, Maria Cristina da Silva Lourenço, Luciano Antonio Digiampietri, Philip Noel Suffys, Sylvia Cardoso Leão, Cristina Viana-Niero
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Five mycobacterial isolates from sewage were classified as members of the genus Mycobacterium but presented inconclusive species assignments. Thus, the isolates (MYC017, MYC098, MYC101, MYC123 and MYC340) were analyzed by phenotypical, biochemical, m
Externí odkaz:
https://doaj.org/article/371f550e9aa24579a4e2e046175ac938
Autor:
Leonardo Souza Esteves, Lia Lima Gomes, Daniela Brites, Fátima Cristina Onofre Fandinho, Marcela Bhering, Márcia Aparecida da Silva Pereira, Emilyn Costa Conceição, Richard Salvato, Bianca Porphirio da Costa, Reginalda Ferreira de Melo Medeiros, Paulo Cesar de Souza Caldas, Paulo Redner, Margareth Pretti Dalcolmo, Vegard Eldholm, Sebastien Gagneux, Maria Lucia Rossetti, Afrânio Lineu Kritski, Philip Noel Suffys
Publikováno v:
Antibiotics, Vol 13, Iss 6, p 496 (2024)
The present study aimed to determine the genetic diversity of isolates of Mycobacterium tuberculosis (Mtb) from presumed drug-resistant tuberculosis patients from several states of Brazil. The isolates had been submitted to conventional drug suscepti
Externí odkaz:
https://doaj.org/article/1b5e78afb56f4055bbc44b17d2fdfd7c
Autor:
Márcia Quinhones P. Lopes, Raquel Lima F. Teixeira, Pedro Hernan Cabello, José Augusto C. Nery, Anna Maria Sales, Edilbert Pellegrini Nahn J. R., Marilda Vieira Moreira, Ewalda Von Rosen Stahlke, Lia Gonçalves Possuelo, Maria Lucia R. Rossetti, Marcelo F. Rabahi, Luciana F. M. Silva, Patrícia Almeida Leme, William John Woods, Mauricio Lisboa Nobre, Maria Leide Wan-Del-Rey de Oliveira, Kazuê Narahashi, Milde Cavalcanti, Philip Noel Suffys, Sotiria Boukouvala, Maria Eugênia N. Gallo, Adalberto Rezende Santos
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Introduction: Several polymorphisms altering the NAT2 activity have already been identified. The geographical distribution of NAT2 variants has been extensively studied and has been demonstrated to vary significantly among different ethnic population
Externí odkaz:
https://doaj.org/article/eb92ce59510f48f8a05329b36d2ff020
Autor:
Amanda Juliane Finardi, Nathan Guilherme de Oliveira, Eloise Brasil de Moraes, Lavínia Cássia Ferreira Batista, Bruna Eduarda Bortolomai, Philip Noel Suffys, Ida Maria Foschiani Dias Baptista
Publikováno v:
Revista da Sociedade Brasileira de Medicina Tropical, Vol 56 (2023)
ABSTRACT Background: Brazil has the second largest number of leprosy cases worldwide, and the state of São Paulo has been considered non-endemic since 2006. Methods: We analyzed 16 variable number tandem repeats loci and three single nucleotide poly
Externí odkaz:
https://doaj.org/article/fdb4a0f57a5a4708a397f764f0822091
Autor:
Taís Ramalho dos Anjos, Vinícius Silva Castro, Edson Silva Machado Filho, Philip Noel Suffys, Harrison Magdinier Gomes, Rafael Silva Duarte, Eduardo Eustáquio de Souza Figueiredo, Ricardo César Tavares Carvalho
Publikováno v:
Frontiers in Veterinary Science, Vol 9 (2022)
The species Mycobacterium tuberculosis variant bovis (M. tuberculosis var. bovis) is associated with tuberculosis, mainly in cattle and buffaloes. This pathogen has the potential to infect other mammals, including humans. Tuberculosis caused by M. tu
Externí odkaz:
https://doaj.org/article/36237f26bb9e440fbfe1b9cca3077c76
Autor:
Lida Jouca de Assis Figueredo, Isabela Neves de Almeida, Claudio José Augusto, Valéria Martins Soares, Philip Noel Suffys, Wânia da Silva Carvalho, Silvana Spíndola de Miranda
Publikováno v:
International Journal of Mycobacteriology, Vol 9, Iss 4, Pp 368-372 (2020)
Background: Heteroresistance is the coexistence of susceptible and resistant strains in the same individual, considered the preliminary step for total resistance, and can stem from mixed infection or clonal heterogeneity. The aim of this study was to
Externí odkaz:
https://doaj.org/article/394b710c58e645f9a73ff0aa3d29c9dd