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of 3
pro vyhledávání: '"Philip N. Rees"'
Autor:
Philip N. Rees, Andrew L. H. Webster, Michael A. Skinnider, Chris A. Dejong, Haoxin Li, Mclean R Edwards, Chad W. Johnston, Nathan A. Magarvey, Gregory M. Chen
Publikováno v:
Nature Chemical Biology. 12:1007-1014
Polyketides (PKs) and nonribosomal peptides (NRPs) are profoundly important natural products, forming the foundations of many therapeutic regimes. Decades of research have revealed over 11,000 PK and NRP structures, and genome sequencing is uncoverin
Autor:
Shawn French, János Bérdy, Eric D. Brown, Gregory M. Chen, Chris A. Dejong, Philip N. Rees, Michael A. Skinnider, Chad W. Johnston, Dennis Y. Liu, Chelsea G Walker, Nathan A. Magarvey
Publikováno v:
Nature Chemical Biology. 12:233-239
Antibiotics are essential for numerous medical procedures, including the treatment of bacterial infections, but their widespread use has led to the accumulation of resistance, prompting calls for the discovery of antibacterial agents with new targets
Autor:
Chad W. Johnston, Robyn Edgar, Nathan A. Magarvey, Nishanth J. Merwin, Michael A. Skinnider, Philip N. Rees, Chris A. Dejong
Publikováno v:
Proceedings of the National Academy of Sciences. 113
Microbial natural products are an evolved resource of bioactive small molecules, which form the foundation of many modern therapeutic regimes. Ribosomally synthesized and posttranslationally modified peptides (RiPPs) represent a class of natural prod