Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Philip N. McFadden"'
Publikováno v:
Journal of Applied Toxicology. 24:317-321
Joseph J. Pancrazio, Philip N. McFadden, Shimshon Belkin and Robert S. Marks* 1 Center for Bio/Molecular Science and Engineering, Code 6900, US Naval Research Laboratory, Washington, DC 20375, USA 2 Department of Biochemistry and Biophysics, Oregon S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0bb3b6565b9f984e6e8f0bf9235f1ac1
https://doi.org/10.1002/jat.1032
https://doi.org/10.1002/jat.1032
Publikováno v:
Pigment Cell Research. 15:19-26
Fish chromatophores from Betta splendens are used as the cytosensor element in the development of a portable microscale device capable of detecting certain environmental toxins and bacterial pathogens by monitoring changes in pigment granule distribu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::069bca14607568719e8468abd03baadc
https://doi.org/10.1034/j.1600-0749.2002.00069.x
https://doi.org/10.1034/j.1600-0749.2002.00069.x
Autor:
Tonya R Danosky, Philip N. McFadden
Publikováno v:
Biosensors and Bioelectronics. 12:925-936
The activities of fish chromatophores, the colorful living cells in the skin and scales of fish, were tested for their suitability as optically interfaced, digitally processed biosensors of the chemical environment. Norepinephrine and one of its phar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01875413c1862f6663c37e79e0613864
https://doi.org/10.1016/s0956-5663(97)00028-6
https://doi.org/10.1016/s0956-5663(97)00028-6
Publikováno v:
Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology. 117:379-385
Protein- l -isoaspartyl ( d -aspartyl) O-methyltransferase (E.C. 2.1.1.77) is a well-conserved and widely distributed protein repair enzyme that methylates isomerized or racemized aspartyl residues in age-damaged proteins. We exploited the availabili
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66690a1222c7743564a0c2971d025b05
https://doi.org/10.1016/s0305-0491(96)00333-1
https://doi.org/10.1016/s0305-0491(96)00333-1
Autor:
Philip N. McFadden, Darin J. Weber
Publikováno v:
Journal of Protein Chemistry. 16:257-267
Injury to rat blood vessels in vivo was found to release intracellular pools of protein D-aspartyl/L-isoaspartyl carboxyl methyltransferase (PIMT) into the extracellular milieu, where it becomes trapped. This trapped cohort of PIMT is able to utilize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba709e1c0802a2a72ac380d9cdf2828
https://doi.org/10.1023/a:1026300924908
https://doi.org/10.1023/a:1026300924908
Publikováno v:
Journal of Protein Chemistry. 15:115-122
Protein (D-aspartyl/L-isoaspartyl) carboxyl methyltransferase (PCM, E.C. 2.1.1.77) was previously shown to be enzymatically methyl esterified in an autocatalytic manner at altered aspartyl residues; methyl esters are observed in a subpopulation of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d17b024c9024696aaa620615407ffdde
https://doi.org/10.1007/bf01886817
https://doi.org/10.1007/bf01886817
Autor:
Philip N. McFadden, Jeb Y. VanDenburg
Publikováno v:
Journal of Protein Chemistry. 14:291-297
Two nonionic-detergent-insoluble proteins are induced early in the nerve growth factor (NGF)-induced neuronal differentiation of PC12 cells. The pools of these two proteins then disappear from the insoluble fraction after a few days of continued expo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26360dba0c480284e19cd41620608b51
https://doi.org/10.1007/bf01886786
https://doi.org/10.1007/bf01886786
Publikováno v:
Journal of Protein Chemistry. 14:275-282
A 6M urea-insoluble form of tyrosine hydroxylase (THi) was detected in PC12 pheochromocytoma cells by western blotting immunodetection methods, and the characteristics and mechanisms of formation of this insoluble species were investigated. THi accou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81d7530643f5b77a026c9084e349454a
https://doi.org/10.1007/bf01886784
https://doi.org/10.1007/bf01886784
Autor:
Darin J. Weber, Philip N. McFadden
Publikováno v:
Journal of Protein Chemistry. 14:283-289
About 5% of the total cellular protein synthesized in exponentially dividing PC12 phenochromocytoma cells remains insoluble after extractions with aqueous buffer, nonionic detergent, and a strong denaturant, 6 M urea. Single- and double-radiolabel pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7b8f8f15b93d31ef369d5095564d7e
https://doi.org/10.1007/bf01886785
https://doi.org/10.1007/bf01886785
Autor:
Philip N. McFadden, Amy L. Kimzey
Publikováno v:
Journal of Protein Chemistry. 13:537-546
The methyl group from S-adenosylmethionine (AdoMet) is transferred into hemoglobin without any evident involvement of an enzyme. There are multiple sites for incorporation of the methyl group into hemoglobin, since both alpha and beta chains are meth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fc31a02807171e2629d73fcdd0830bc
https://doi.org/10.1007/bf01901535
https://doi.org/10.1007/bf01901535