Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Philip Meade"'
Autor:
Kristien Van Reeth, Anna Parys, José Carlos Mancera Gracia, Ivan Trus, Koen Chiers, Philip Meade, Sean Liu, Peter Palese, Florian Krammer, Elien Vandoorn
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Vaccines that protect against any H1N1 influenza A virus strain would be advantageous for use in pigs and humans. Here, we try to induce a pan-H1N1 antibody response in pigs by sequential vaccination with antigenically divergent H1N1 strains
Externí odkaz:
https://doaj.org/article/3f2b82ff53d24547bc30298e3d7a0e1f
Autor:
Johannes B. Goll, Aarti Jain, Travis L. Jensen, Rafael Assis, Rie Nakajima, Algis Jasinskas, Lynda Coughlan, Sami R. Cherikh, Casey E. Gelber, S. Khan, D. Huw Davies, Philip Meade, Daniel Stadlbauer, Shirin Strohmeier, Florian Krammer, Wilbur H. Chen, Philip L. Felgner
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Current seasonal and pre-pandemic influenza vaccines induce short-lived predominantly strain-specific and limited heterosubtypic responses. To better understand how vaccine adjuvants AS03 and MF59 may provide improved antibody responses to v
Externí odkaz:
https://doaj.org/article/5613d64cac7c4b24947caa4bc89283fe
Publikováno v:
Emerging Microbes and Infections, Vol 8, Iss 1, Pp 155-168 (2019)
ABSTRACTInfluenza viruses of the H4 subtype are widespread in wild birds, circulate in domestic poultry, readily infect mammals, and tolerate the insertion of a polybasic cleavage site. In addition, serological evidence suggests that humans working w
Externí odkaz:
https://doaj.org/article/582c7f4d354942549a81733b4d561a7b
Autor:
Philip Meade, Guillermina Kuan, Shirin Strohmeier, Hannah E. Maier, Fatima Amanat, Angel Balmaseda, Kimihito Ito, Ericka Kirkpatrick, Andres Javier, Lionel Gresh, Raffael Nachbagauer, Aubree Gordon, Florian Krammer
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT In contrast to influenza virus vaccination, natural infection induces long-lived and relatively broad immune responses. However, many aspects of the antibody response to natural infection are not well understood. Here, we assessed the immune
Externí odkaz:
https://doaj.org/article/8949058e563642218bd96502680e85f1
Publikováno v:
Emerging Microbes and Infections, Vol 6, Iss 1, Pp 1-9 (2017)
Avian influenza viruses pose a serious zoonotic threat, in part because current seasonal influenza virus vaccines only offer strain-specific protection, instead of heterosubtypic or universal protection against influenza virus infection. Understandin
Externí odkaz:
https://doaj.org/article/864a1d60200745c0a462374fe6fcdc59
Autor:
Sun-Young Sunwoo, Michael Schotsaert, Igor Morozov, Anne Sally Davis, Yuhao Li, Jinhwa Lee, Chester McDowell, Philip Meade, Raffael Nachbagauer, Adolfo García-Sastre, Wenjun Ma, Florian Krammer, Juergen A. Richt
Publikováno v:
Vaccines, Vol 6, Iss 4, p 80 (2018)
In the published article, “A Universal Influenza Virus Vaccine Candidate Tested in a Pig Vaccination-Infection Model in the Presence of Maternal Antibodies. [...]
Externí odkaz:
https://doaj.org/article/1be4e7d0033447ef8cd3b181009bfea8
Autor:
Sun-Young Sunwoo, Michael Schotsaert, Igor Morozov, Anne Sally Davis, Yuhao Li, Jinhwa Lee, Chester McDowell, Philip Meade, Raffael Nachbagauer, Adolfo García-Sastre, Wenjun Ma, Florian Krammer, Juergen A. Richt
Publikováno v:
Vaccines, Vol 6, Iss 3, p 64 (2018)
The antigenically conserved hemagglutinin stalk region is a target for universal influenza virus vaccines since antibodies against it can provide broad protection against influenza viruses of different subtypes. We tested a universal influenza virus
Externí odkaz:
https://doaj.org/article/6882617696ba4052abb083941bbf4caa
Autor:
Philip Meade
Publikováno v:
Social Work and Society, Vol 4, Iss 1 (2006)
The Second Global Report on Child Labour presented by the International Labour Office (ILO) in May 2006 is titled: “The End of Child Labour: Within Reach”. This astoundingly optimistic scenario refers to the global decline in numbers of child lab
Externí odkaz:
https://doaj.org/article/6dffac557891407386a1553a91e67802
Autor:
Philip Meade, Shirin Strohmeier, Maria Carolina Bermúdez-González, Adolfo García-Sastre, Peter Palese, Viviana Simon, Florian Krammer
Publikováno v:
J Virol
Current influenza virus vaccines have to be closely matched to circulating strains to provide good protection and antigenic drift and emerging pandemic influenza virus strains present a difficult challenge for them. Universal influenza virus vaccines
Autor:
Shambhunath Choudhary, Isis Kanevsky, Soner Yildiz, Rani S. Sellers, Kena A. Swanson, Tania Franks, Raveen Rathnasinghe, Raquel Munoz-Moreno, Sonia Jangra, Olga Gonzalez, Philip Meade, Timothy Coskran, Jessie Qian, Thomas A. Lanz, Jillian G. Johnson, Cassandra A Tierney, Justin D. Smith, Kristin Tompkins, Arthur Illenberger, Paula Corts, Tara Ciolino, Philip R. Dormitzer, Edward J. Dick, Vinay Shivanna, Shannan Hall-Ursone, Journey Cole, Deepak Kaushal, Jane A. Fontenot, Carles Martinez-Romero, Meagan McMahon, Florian Krammer, Michael Schotsaert, Adolfo García-Sastre
Publikováno v:
Toxicologic Pathology
Coronavirus disease 2019 (COVID-19) in humans has a wide range of presentations, ranging from asymptomatic or mild symptoms to severe illness. Suitable animal models mimicking varying degrees of clinical disease manifestations could expedite developm