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pro vyhledávání: '"Philip Martin Arlen"'
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Natural killer (NK) cells are cellular components of the innate immune system that can recognize and suppress the proliferation of cancer cells. NK cells can eliminate cancer cells through direct lysis, by secreting perforin and granzymes, or through
Externí odkaz:
https://doaj.org/article/41e082bd691c4446858d65ad99eec043
Autor:
Christopher Browning Cole, Maria Pia Morelli, Massimo Fantini, Maria Fergusson, Sharon A. Mavroukakis, Anjum Zaki, Kwong Y. Tsang, Philip Martin Arlen, Christina M. Annunziata
Publikováno v:
Journal of Clinical Oncology. 40:2531-2531
2531 Background: NEO201 is a humanized IgG1 monoclonal antibody generated against tumor-associated antigens from colorectal cancer which binds specifically to tumor-associated CEACAM-5 and CEACAM-6 variants without binding CECAM 5/6 on normal epithel