Zobrazeno 1 - 10
of 68
pro vyhledávání: '"Philip M. Short"'
Autor:
Margaret M Band, Hollian Richardson, Jennifer Pollock, Heather Barclay, Simon Finch, Gourab Chowdhury, Devesh Dhasmana, Philip M. Short, James D. Chalmers, Diane Cassidy, Rekha Chaudhuri, Mike Lonergan, Furrah Hussain, Andrew Mackenzie, Pauline Billingham, Alison Dicker, Andrew Paul Smith, Megan Crichton, Holly R. Keir, Clare Clarke, Mohammad Majid Paracha
Publikováno v:
Airway pharmacology and treatment.
Background: The MUSIC study is testing the impact of inhaled corticosteroid (ICS) and bronchodilator (LABA/LAMA) treatment on the upper and lower airway microbiome in patients with COPD (NCT02972476). Patients receiving ICS at baseline withdrew thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26f2cef6e13dd334aa8e114a42b8b1e0
https://doi.org/10.1183/13993003.congress-2020.3253
https://doi.org/10.1183/13993003.congress-2020.3253
Publikováno v:
Annals of Allergy, Asthma & Immunology. 118:179-185
Background Inhaled corticosteroid (ICS) titration in asthma is primarily based on symptoms and pulmonary function. ICSs may not be increased on this basis despite residual airway inflammation. Objective To compare the dose-response relationships of I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee88a5177b901fcf2733083e12766e89
https://doi.org/10.1016/j.anai.2016.11.018
https://doi.org/10.1016/j.anai.2016.11.018
Autor:
William Anderson, Ashley Morrison, RW Kuo, RA Ross, Brian J. Lipworth, Sunny Jabbal, Philip M. Short
Publikováno v:
An update in lung physiology.
Background Beta-blockers (BB) are underused in COPD despite evidence for reducing mortality from cardiovascular comorbidities. Beta-1 selective antagonists such as bisoprolol (BIS) may cause bronchoconstriction due to dose related beta-2 blockade. Ce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::50e6e0c0e106b6072519d8a949f02b6b
https://doi.org/10.1136/thorax-2019-btsabstracts2019.83
https://doi.org/10.1136/thorax-2019-btsabstracts2019.83
Publikováno v:
Annals of Allergy, Asthma & Immunology. 115:17-20
Background Impulse oscillometry (IOS) is a novel method of assessing airway resistance. IOS is rarely used in assessing airway resistance after bronchoprovocation in adult asthma. Objective To ascertain the degree of change in IOS measurements seen i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6594fe1d2238c4485aa89d3c2aa168ce
https://doi.org/10.1016/j.anai.2015.04.022
https://doi.org/10.1016/j.anai.2015.04.022
Publikováno v:
Lung. 193:487-495
Left ventricular hypertrophy (LVH) is a significant cardiac risk factor, associated with increased mortality. The impact of LVH on mortality in chronic obstructive pulmonary disease (COPD) is unknown. We evaluated the impact of LVH on mortality in CO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a23da282db7de53533950db87df3cfbd
https://doi.org/10.1007/s00408-015-9724-8
https://doi.org/10.1007/s00408-015-9724-8
Autor:
Sunny Jabbal, Philip M. Short, Brian Lipworth, William Anderson, Ashley Morrison, Arvind Manoharan
Publikováno v:
Airway Pharmacology and Treatment.
BACKGROUND Beta-blockers remain underused in patients with chronic obstructive pulmonary disease (COPD) and cardiovascular disease. AIM We compared how different inhaled therapies affect tolerability of bisoprolol and carvedilol in moderate to severe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9609494b8fd429654309352ac272cce
https://doi.org/10.1183/1393003.congress-2017.pa3247
https://doi.org/10.1183/1393003.congress-2017.pa3247
Autor:
Philip M. Short, Peter A. Williamson, Arun Nair, Brian Lipworth, Lorna McKinlay, Patricia Burns
Publikováno v:
European journal of clinical pharmacology. 73(6)
Purpose This study compares the in vivo relative lung bioavailability of Hydrofluoroalkane (HFA) Seretide delivered via unprimed and unwashed Aerochamber Plus (AP) or Volumatic (VM) spacers, a integrated breath-actuated vortex Synchro-Breathe (SB) de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a751159edf5cdb67f5a5685c0190183c
https://pubmed.ncbi.nlm.nih.gov/21240480
https://pubmed.ncbi.nlm.nih.gov/21240480
Publikováno v:
Clinical Science. 127:635-643
The murine asthma model shows that switching off airway β2 receptors with an inverse agonist may confer anti-inflammatory effects as well as corticosteroid-sparing activity. We have assessed for any corticosteroid-sparing effects of propranolol, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2d512b0a6e57f2b6519b36df7b64ab
https://doi.org/10.1042/cs20140249
https://doi.org/10.1042/cs20140249
Autor:
Aran Singanayagam, Stuart Schembri, Philip M. Short, James D. Chalmers, Michelle Harrison, Peter A. Williamson
Publikováno v:
Thorax. 69:609-615
Introduction Evidence suggests that platelets play a significant role in inflammation in addition to their role in thrombosis. Systemic inflammation is linked to poor short and long term outcomes in COPD. Increased platelet activation has been report
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b560d4e5ade01083b7ed883e6bdbfc57
https://doi.org/10.1136/thoraxjnl-2013-203996
https://doi.org/10.1136/thoraxjnl-2013-203996
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 187:1308-1314
Rationale: Unblinded studies have shown improvements in airway hyperresponsiveness with chronic nadolol in steroid-naive patients with asthma.Objectives: To assess the effects of chronic nonselective β-blockade as add-on to inhaled corticosteroids (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1956daa18535f2459b32c683ffce5c3f
https://doi.org/10.1164/rccm.201212-2206oc
https://doi.org/10.1164/rccm.201212-2206oc