Výsledky vyhledávání - "Philip M. Pelphrey"

Selective inhibitor of proteasome's caspase-like sites sensitizes cells to specific inhibition of chymotrypsin-like sites

Autor: Michael Screen, Marcella M. Lucas, Alexandre A. Pletnev, Robert Tokhunts, Dennis L. Wright, Omar Amir, Matthew Britton, Herman S. Overkleeft, Martijn Verdoes, Ayrton L. Goddard, Sondra L. Downey, Alexei F. Kisselev, Philip M. Pelphrey

Publikováno v: Chemistrybiology. 16(12)

Proteasomes degrade most proteins in mammalian cells and are established targets of anti-cancer drugs. All eukaryotic proteasomes have three types of active sites: chymotrypsin-like, trypsin-like, and caspase-like. Chymotrypsin-like sites are the mos

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::36a80c2ee9d34929f39396358c7ebb1c
https://pubmed.ncbi.nlm.nih.gov/20064438

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání