Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Philip M. Iannaccone"'
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Externí odkaz:
https://doaj.org/article/7cd3d6247b814380a381ae7b42d77cf1
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/ffed688fec1a499b8aad484e7d526e3b
Autor:
Philip M. Iannaccone, Joon Won Yoon, Xenia A. Glukhova, Xiao-Nan Li, Robert L. Taylor, Yekaterina Galat, Mariana Perepitchka, Igor P. Beletsky, Vasiliy Galat, David O. Walterhouse, Haigang Gu
Publikováno v:
Stem Cells (Dayton, Ohio)
GLI1 is one of three GLI family transcription factors that mediate Sonic Hedgehog signaling, which plays a role in development and cell differentiation. GLI1 forms a positive feedback loop with GLI2 and likely with itself. To determine the impact of
Publikováno v:
Reference Module in Biomedical Sciences ISBN: 9780128012383
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cd599c6b56b3f8191be35a242751a57
https://doi.org/10.1016/b978-0-12-824010-6.00017-4
https://doi.org/10.1016/b978-0-12-824010-6.00017-4
Publikováno v:
Oncotarget
Trisomy 21 (T21), known as Down syndrome (DS), is a widely studied chromosomal abnormality. Previous studies have shown that DS individuals have a unique cancer profile. While exhibiting low solid tumor prevalence, DS patients are at risk for hematol
Autor:
Irina Elcheva, Mariana Perepitchka, Vasiliy Galat, Stephen Iannaccone, Philip M. Iannaccone, Yekaterina Galat
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-16 (2020)
Scientific Reports
Scientific Reports
Down syndrome (DS) is a congenital disorder caused by trisomy 21 (T21). It is associated with cognitive impairment, muscle hypotonia, heart defects, and other clinical anomalies. At the same time, individuals with Down syndrome have lower prevalence
Autor:
David J. Robbins, Robert L. Taylor, Kathrine B. Sylvestersen, Stephen Iannaccone, Ronnie Childs, King Fu Leong, Joon Won Yoon, David O. Walterhouse, Jun Long, Philip M. Iannaccone, Michael L. Nielsen
Publikováno v:
Taylor, R, Long, J, Yoon, J W, Childs, R, Sylvestersen, K B, Nielsen, M L, Leong, K-F, Iannaccone, S, Walterhouse, D O, Robbins, D J & Iannaccone, P 2019, ' Regulation of GLI1 by cis DNA elements and epigenetic marks ', DNA Repair, vol. 79, pp. 10-21 . https://doi.org/10.1016/j.dnarep.2019.04.011
DNA repair
DNA repair
GLI1 is one of three transcription factors (GLI1, GLI2 and GLI3) that mediate the Hedgehog signal transduction pathway and play important roles in normal development. GLI1 and GLI2 form a positive-feedback loop and function as human oncogenes. The mo
Publikováno v:
Pediatric Research. 83:258-266
Pediatric patients with a neurogenic urinary bladder, caused by developmental abnormalities including spina bifida, exhibit chronic urological problems. Surgical management in the form of enterocystoplasty is used to enlarge the bladder, but is assoc
Autor:
Philip M. Iannaccone, Mariana Perepitchka, Vasiliy Galat, Mary J.C. Hendrix, Lawrence J. Jennings, Yekaterina Galat
Publikováno v:
Stem Cells and Development
Induced pluripotent stem cells (iPSCs) have enormous potential in regenerative medicine and disease modeling. It is now felt that clinical trials should be performed with iPSCs derived with nonintegrative constructs. Numerous studies, however, includ
Publikováno v:
International Journal of Environmental Research and Public Health
International Journal of Environmental Research and Public Health, Vol 17, Iss 5462, p 5462 (2020)
Volume 17
Issue 15
International Journal of Environmental Research and Public Health, Vol 17, Iss 5462, p 5462 (2020)
Volume 17
Issue 15
The conversion of lysine to glutamate is needed for signaling in all plants and animals. In mouse embryonic stem (mES) cells, and probably their progenitors, endogenous glutamate production and signaling help maintain cellular pluripotency and prolif