Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Philip M. Carabateas"'
Autor:
Dean A. Haycock, Michael Eissenstat, Joan E. Kuster, Daniel Luttinger, Frances M. Casiano, Kurt A. Josef, Alexandros Makriyannis, Virendra Kumar, James H. Ackerman, Atmaram D. Khanolkar, Jeffrey Abt, Bacon Edward R, Thomas E. D'Ambra, Renee Arnold, John D. Weaver, Malcolm R. Bell, Susan M. Chippari, Joan I. Stevenson, W. Adam G. Hill, Susan Jean Ward, Philip M. Carabateas
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:17-22
Aminoalkylindoles (AAIs) with potent cannabinoid agonist activity have been synthesized where the aminoalkyl chain is attached to the indole ring via a carbon atom of the cyclic amine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8be4d4fe848aed4d5576b63484012c02
https://doi.org/10.1016/0960-894x(95)00560-g
https://doi.org/10.1016/0960-894x(95)00560-g
Autor:
Robert E. Johnson, Paul J. Silver, Russell Becker, Nancy C. Birsner, Eric A. Bohnet, G. Maurice Briggs, Carl A. Busacca, Paul Canniff, Philip M. Carabateas, Thomas D'Ambra, Ronald L. Dundore, Jen-Sen Dung, Christopher C. Chadwick, Alan M. Ezrin, William Gorczyca, Peter G. Habeeb, Patrick Horan, Douglas S. Krafte, Gary Pelling, Bernard O'Connor, Manohar T. Saindane, Donald C. Schlegel, Gerald P. Stankus, John Swestock, Walter A. Volberg
Publikováno v:
Journal of Medicinal Chemistry. 38:2551-2556
A series of 4,5-dihydro-3-[2-(methanesulfonamidophenyl)ethyl]-1-phenyl- 1H-2,4-benzodiazepines has been identified as potential antiarrhythmic agents that interact at the delayed rectifier myocardial potassium channels (IKr) and prolong the ventricul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::efc92eadd0db68fb0531e2763844b686
https://doi.org/10.1021/jm00014a008
https://doi.org/10.1021/jm00014a008
Autor:
David M. Sedlock, George Y. Lesher, Manohar Saindane, Sol J. Daum, Philip M. Carabateas, James B. Rake, Dorff Peter H, Michael Reuman, Robert B. Perni, S. A. Coughlin, Patrick O. Pennock, Mark P. Wentland, Baldev Singh, Monte D. Gruett
Publikováno v:
Journal of Medicinal Chemistry. 38:2531-2540
The palladium-catalyzed coupling of 3- and 4-(trialkylstannyl)pyridines with 7-bromo or 7-chloro 1-substituted 1,4-dihydro-4-oxo-3-quinolinecarboxylates has provided access to the corresponding 1-substituted 1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dd6be818bf2933c98aef67b62f79296
https://doi.org/10.1021/jm00014a005
https://doi.org/10.1021/jm00014a005
Autor:
Kimberly G. Estep, Douglas S. Krafte, Nancy Dugrenier, Garry M. Pilling, Gerald P. Stankus, Philip M. Carabateas, Kurt A. Josef, Squire Rumney, Paul C. Canniff, William P. Gorczyca, Alan M. Ezrin, Bacon Edward R, G. Maurice Briggs, Kathleen Dillon, Walter A. Volberg
Publikováno v:
Journal of Medicinal Chemistry. 38:2582-2595
Purine-based analogs of SDZ 211-500 (5) were prepared and evaluated as inactivation modifiers of guinea pig or human cardiac sodium (Na) channels expressed in Xenopus oocytes. Substances which remove or slow the Na channel inactivation process in car
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46623797c69488b26414a46649968053
https://doi.org/10.1021/jm00014a011
https://doi.org/10.1021/jm00014a011
Autor:
Chakrapani Subramanyam, William G. Earley, Joseph R. Wetzel, John P. Mallamo, Diane L. DeHaven-Hudkins, Gary M. Pilling, Philip M. Carabateas, Timothy Allen, Rudolph K. Kullnig
Publikováno v:
Journal of Medicinal Chemistry. 38:2483-2489
The synthesis and in vitro and in vivo evaluation of 12,13-cycloalkyl-6,11-ethanobenzo[b]-quinolizidines, a new class of noncompetitive N-methyl-D-aspartate (NMDA) antagonists acting at the PCP site on the NMDA receptor complex, is reported. Structur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef324d4752d59b28c371c6e64016ffb3
https://doi.org/10.1021/jm00013a025
https://doi.org/10.1021/jm00013a025
Autor:
D. Rosi, Robert B. Perni, M. J. Castaldi, Dorff Peter H, Mark P. Wentland, R. P. Brundage, F. J. Dutko, Edward R. Bacon, M. G. Woods, D. C. Young, T. R. Bailey, Rudolph K. Kullnig, Philip M. Carabateas, M. L. Drozd
Publikováno v:
ChemInform. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34d8888c4ec5a9944677e871a58a1ab5
https://doi.org/10.1002/chin.199335189
https://doi.org/10.1002/chin.199335189
Autor:
J. T. Hane, James H. Ackerman, Philip M. Carabateas, John Swestock, Donald Charles Schlegel, R. B. Perni, Chester J. Opalka, J. L. Jun. Herrmann, Robert E. Johnson, J. H. Tatlock, N. C. Birsner
Publikováno v:
ChemInform. 23
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::219686f4bf4ab48d03dd9966bcbb4bfd
https://doi.org/10.1002/chin.199204131
https://doi.org/10.1002/chin.199204131
Autor:
D. S. Krafte, P. A. Pareene, J. T. Hane, Robert E. Johnson, C. Becker, U. J. Salvador, N. C. Birsner, Rudolph K. Kullnig, C. C. Chadwick, E. R. Baizman, R. H. Bell, Philip M. Carabateas, William F. Michne, C. A. Busacca, J. L. Jun. Herrmann, K. A. Josef, Bernard O'Connor, E. A. Bohnet, Monte D. Gruett, R. B. Perni
Publikováno v:
ChemInform. 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bacd258dcdefc59c1d2e579325ebfc24
https://doi.org/10.1002/chin.199411194
https://doi.org/10.1002/chin.199411194
Autor:
Monte D. Gruett, Mark P. Wentland, Michael Reuman, Philip M. Carabateas, Robert B. Perni, Patrick O. Pennock, S. A. Coughlin, Manohar Saindane, David M. Sedlock, James B. Rake, Dorff Peter H, George Y. Lesher, Sol J. Daum, Baldev Singh
Publikováno v:
ChemInform. 26
The palladium-catalyzed coupling of 3- and 4-(trialkylstannyl)pyridines with 7-bromo or 7-chloro 1-substituted 1,4-dihydro-4-oxo-3-quinolinecarboxylates has provided access to the corresponding 1-substituted 1,4-dihydro-4-oxo-7-pyridinyl-3-quinolinec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a3dd78d36c2592f5515425793d187d2
https://doi.org/10.1002/chin.199545173
https://doi.org/10.1002/chin.199545173
Autor:
John P. Mallamo, Eissenstat Ma, David Cutcliffe, Philip M. Carabateas, Thomas R. Bailey, Guy D. Diana, Daniel C. Pevear, Paul J. Kowalczyk, Vahan Akullian
Publikováno v:
Journal of Medicinal Chemistry. 35:4628-4633
A variety of heterocyclic analogs of Win 54954 have been synthesized and tested in vitro against human rhinovirus type 14 (HRV-14) in a plaque reduction assay. The more active compounds were tested against 14 additional serotypes, and the concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090722ad427e3e628295100fe710be30
https://doi.org/10.1021/jm00102a017
https://doi.org/10.1021/jm00102a017