Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Philip M. Borden"'
Autor:
Mark A. Lobas, Rongkun Tao, Jun Nagai, Mira T. Kronschläger, Philip M. Borden, Jonathan S. Marvin, Loren L. Looger, Baljit S. Khakh
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
ATP has essential roles in cell signalling and energy homeostasis and biosensors to detect it have many potential applications. Here, the authors develop a new ATP sensor that can be targeted to the membrane or cytosol.
Externí odkaz:
https://doaj.org/article/7f5127aea1404556aa178bc1605413dd
Autor:
Kallol Bera, Aron Kamajaya, Amol V. Shivange, Anand K. Muthusamy, Aaron L. Nichols, Philip M. Borden, Stephen Grant, Janice Jeon, Elaine Lin, Ishak Bishara, Theodore M. Chin, Bruce N. Cohen, Charlene H. Kim, Elizabeth K. Unger, Lin Tian, Jonathan S. Marvin, Loren L. Looger, Henry A. Lester
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 13 (2019)
The target for the “rapid” (100-fold selectivity over other ligands tested, including R-ketamine. We targeted each of the sensors to either the plasma membrane (PM) or the endoplasmic reticulum (ER). Measurements on these biosensors expressed in
Externí odkaz:
https://doaj.org/article/4397d649b8754ebaa97c121f59eaa73b
Autor:
Aaron L Nichols, Zack Blumenfeld, Chengcheng Fan, Laura Luebbert, Annet EM Blom, Bruce N Cohen, Jonathan S Marvin, Philip M Borden, Charlene H Kim, Anand K Muthusamy, Amol V Shivange, Hailey J Knox, Hugo Rego Campello, Jonathan H Wang, Dennis A Dougherty, Loren L Looger, Timothy Gallagher, Douglas C Rees, Henry A Lester
Publikováno v:
eLife, Vol 11 (2022)
Externí odkaz:
https://doaj.org/article/098460172c5e405ebfd89ac4744a4398
Autor:
Aaron L Nichols, Zack Blumenfeld, Chengcheng Fan, Laura Luebbert, Annet EM Blom, Bruce N Cohen, Jonathan S Marvin, Philip M Borden, Charlene H Kim, Anand K Muthusamy, Amol V Shivange, Hailey J Knox, Hugo Rego Campello, Jonathan H Wang, Dennis A Dougherty, Loren L Looger, Timothy Gallagher, Douglas C Rees, Henry A Lester
Publikováno v:
eLife, Vol 11 (2022)
Nicotinic partial agonists provide an accepted aid for smoking cessation and thus contribute to decreasing tobacco-related disease. Improved drugs constitute a continued area of study. However, there remains no reductionist method to examine the cell
Externí odkaz:
https://doaj.org/article/4b4e86491b454335b0724b76381431a8
Autor:
W. Sharon Zheng, Yajun Zhang, Roger E. Zhu, Peng Zhang, Smriti Gupta, Limeng Huang, Deepika Sahoo, Kaiming Guo, Matthew E. Glover, Krishna C. Vadodaria, Mengyao Li, Tongrui Qian, Miao Jing, Jiesi Feng, Jinxia Wan, Philip M. Borden, Farhan Ali, Alex C. Kwan, Li Gan, Li Lin, Fred H. Gage, B. Jill Venton, Jonathan S. Marvin, Kaspar Podgorski, Sarah M. Clinton, Miaomiao Zhang, Loren L. Looger, Yulong Li, J. Julius Zhu
Intercellular communication mediated by a large number of neuromodulators diversifies physiological actions, yet neuromodulation remains poorly understood despite the recent upsurge of genetically encoded transmitter sensors. Here, we report the deve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d72cee989f4181c4acd4761a3ca88cb2
https://doi.org/10.1101/2022.10.05.511006
https://doi.org/10.1101/2022.10.05.511006
Autor:
Laura Luebbert, Chengcheng Fan, Zack Blumenfeld, Aaron L Nichols, Annet EM Blom, Bruce N Cohen, Jonathan S Marvin, Philip M Borden, Charlene H Kim, Anand K Muthusamy, Amol V Shivange, Hailey J Knox, Hugo Rego Campello, Jonathan H Wang, Dennis A Dougherty, Loren L Looger, Timothy Gallagher, Douglas C Rees, Henry A Lester
Publikováno v:
eLife, Vol 11 (2022)
Nicotinic partial agonists provide an accepted aid for smoking cessation and thus contribute to decreasing tobacco-related disease. Improved drugs constitute a continued area of study. However, there remains no reductionist method to examine the cell
Autor:
Laura Luebbert, Chengcheng Fan, Zack Blumenfeld, Aaron L Nichols, Annet EM Blom, Bruce N Cohen, Jonathan S Marvin, Philip M Borden, Charlene H Kim, Anand K Muthusamy, Amol V Shivange, Hailey J Knox, Hugo Rego Campello, Jonathan H Wang, Dennis A Dougherty, Loren L Looger, Timothy Gallagher, Douglas C Rees, Henry A Lester
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ba6d7547914bb271a0936a614e02ac3
https://doi.org/10.7554/elife.74648.sa2
https://doi.org/10.7554/elife.74648.sa2
Autor:
Jonathan S. Marvin, Amol V. Shivange, Hailey J. Knox, Loren L. Looger, Henry A. Lester, Charlene H. Kim, Annet E. M. Blom, C. Fan, Timothy Gallagher, Laura Luebbert, Philip M. Borden, Bruce N. Cohen, Aaron L. Nichols, Hugo Rego Campello, Dennis A. Dougherty, Jonathan H. Wang, Zack Blumenfeld, Douglas C. Rees, Anand K. Muthusamy
Nicotinic partial agonists provide an accepted aid for smoking cessation and thus contribute to decreasing tobacco-related disease. Improved drugs constitute a continued area of study. However, there remains no reductionist method to examine the cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10a55da369175a588f45fdc48dd3e8e5
https://doi.org/10.1101/2021.10.04.463082
https://doi.org/10.1101/2021.10.04.463082
Autor:
Parker E. Deal, Jonathan S. Marvin, Loren L. Looger, Abbas Kazemipour, Jonathan P. King, Daniel Flickinger, Ondrej Novak, Jeong Jun Kim, Sarah H. Al-Abdullatif, Eric R. Schreiter, Philip M. Borden, Ahmed S. Abdelfattah, Shaul Druckmann, Kaspar Podgorski, Karel Svoboda, Evan W. Miller
Publikováno v:
Nature methods
Point-scanning two-photon microscopy enables high-resolution imaging within scattering specimens such as the mammalian brain, but sequential acquisition of voxels fundamentally limits its speed. We developed a two-photon imaging technique that scans
Autor:
Philip M. Borden, Kallol Bera, Huan Bao, Bruce N. Cohen, Edwin R. Chapman, Ishak Bishara, Anand K. Muthusamy, Aaron L. Nichols, Jonathan S. Marvin, Amol V. Shivange, Loren L. Looger, Dennis A. Dougherty, Matthew J. Mulcahy, Charlene Kim, Janice Jeon, Saidhbhe L. O'Riordan, Henry A. Lester
Publikováno v:
The Journal of General Physiology
Nicotine dependence is thought to arise in part because nicotine permeates into the endoplasmic reticulum (ER), where it binds to nicotinic receptors (nAChRs) and begins an “inside-out” pathway that leads to up-regulation of nAChRs on the plasma