Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Philip M Kelley"'
Autor:
Darci M Fink, Alicia L Connor, Philip M Kelley, Maria M Steele, Michael A Hollingsworth, Richard M Tempero
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e112737 (2014)
The cellular and physiologic mechanisms that regulate the resolution of inflammation remain poorly defined despite their widespread importance in improving inflammatory disease outcomes. We studied the resolution of two cardinal signs of inflammation
Externí odkaz:
https://doaj.org/article/dbe322dce9f94ec9a459feb1e47c16fe
Publikováno v:
Laboratory investigation; a journal of technical methods and pathology
Postnatal inflammatory lymphangiogenesis presumably requires precise regulatory processes to properly assemble proliferating lymphatic endothelial cells (LECs). The specific mechanisms that regulate the assembly of LECs during new lymphatic vessel sy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7451fbff3508f50a26fc1f15e28fd2f8
https://doi.org/10.1038/labinvest.2015.147
https://doi.org/10.1038/labinvest.2015.147
Autor:
Barbara J. Morley, Marian J. Drescher, Philip M. Kelley, Neeliyath A. Ramakrishnan, Dennis G. Drescher
Publikováno v:
Journal of Biological Chemistry. 289:8750-8766
Mutations in otoferlin, a C2 domain-containing ferlin family protein, cause non-syndromic hearing loss in humans (DFNB9 deafness). Furthermore, transmitter secretion of cochlear inner hair cells is compromised in mice lacking otoferlin. In the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5859d699eaca7ebb1f33054a18f5b982
https://doi.org/10.1074/jbc.m113.480533
https://doi.org/10.1074/jbc.m113.480533
Publikováno v:
The American Journal of Pathology. 182:2418-2428
Inflammation stimulates new lymphatic vessel growth (inflammatory lymphangiogenesis). One key question is how recurrent inflammation, a common clinical condition, regulates lymphatic vessel remodeling. We show here that recurrent inflammation acceler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::641d077be349d101a8fe0a72e8c72861
https://doi.org/10.1016/j.ajpath.2013.02.025
https://doi.org/10.1016/j.ajpath.2013.02.025
Publikováno v:
Journal of Translational Medicine
Background The lymphatic vasculature regulates tissue physiology and immunity throughout life. The self renewal mechanism that maintains the lymphatic vasculature during conditions of homeostasis is unknown. The purpose of this study was to investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cd080d07c789e7b2d382620f8111228
https://doi.org/10.1186/s12967-016-0964-z
https://doi.org/10.1186/s12967-016-0964-z
Publikováno v:
Laboratory Investigation. 91:1643-1651
The fate of newly synthesized lymphatic vessels induced by inflammation is poorly understood. To address this question, we designed experiments to determine the morphologic, phenotypic, and functional differences in regressing lymphatic vessels in th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f446b8a41610ad025706d0a2769226f7
https://doi.org/10.1038/labinvest.2011.121
https://doi.org/10.1038/labinvest.2011.121
Autor:
Philip M. Kelley, Richard M. Tempero
Publikováno v:
Lymphatic Research and Biology. 8:121-126
The structural and molecular properties of the human tonsil lymphatic microvascular system are important to understand as these features likely contribute to fluid balance, immunity, and tumor metastasis. The tonsil is a unique lymphoid organ in that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fd500d69e0451b3f40559c2d6e42ee4
https://doi.org/10.1089/lrb.2009.0026
https://doi.org/10.1089/lrb.2009.0026
Autor:
Deepika Gopalarao, Edward S. Cohn, Walt Jesteadt, William J. Kimberling, Kathryn L. Beauchaine, Philip M. Kelley
Publikováno v:
International Journal of Audiology. 47:11-20
Serial audiograms were analysed for seven subjects, who were homozygous for the 35delG GJB2 mutation. The criterion for determining progression of hearing loss was at least a 1-dB loss in air conduction pure-tone average-3 (ACPTA-3) or ACPTA-4 per ye
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03faaa64092a6a6d35a6dfff853e2aa5
https://doi.org/10.1080/14992020701602087
https://doi.org/10.1080/14992020701602087
Publikováno v:
Perspectives on Hearing and Hearing Disorders in Childhood. 12:14-18
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17162de84952d7c5e4a29bbd0896e65e
https://doi.org/10.1044/hhdc12.2.14
https://doi.org/10.1044/hhdc12.2.14
Autor:
Michael A. Hollingsworth, Maria M. Steele, Alicia L. Connor, Philip M. Kelley, Darci M. Fink, Richard M. Tempero
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 11, p e112737 (2014)
PLoS ONE, Vol 9, Iss 11, p e112737 (2014)
The cellular and physiologic mechanisms that regulate the resolution of inflammation remain poorly defined despite their widespread importance in improving inflammatory disease outcomes. We studied the resolution of two cardinal signs of inflammation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::89fb23d6a9469c5a5d35f24ec3438a87
https://pubmed.ncbi.nlm.nih.gov/25383879
https://pubmed.ncbi.nlm.nih.gov/25383879