Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Philip M Giffard"'
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 13, Iss 7, p e0007511 (2019)
The prevalence of rheumatic heart disease (RHD) in the Aboriginal population of the Australian Northern Territory is high, and Streptococcus pyogenes skin infections likely contribute to this. A promising candidate S. pyogenes "30mer" vaccine is comp
Externí odkaz:
https://doaj.org/article/c0bad0686e434184aa5e21f51d983940
Autor:
Philip M Giffard, Patiyan Andersson, Judith Wilson, Cameron Buckley, Rachael Lilliebridge, Tegan M Harris, Mariana Kleinecke, Kerry-Ann F O'Grady, Wilhelmina M Huston, Stephen B Lambert, David M Whiley, Deborah C Holt
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195454 (2018)
Chlamydia trachomatis infects the urogenital tract (UGT) and eyes. Anatomical tropism is correlated with variation in the major outer membrane protein encoded by ompA. Strains possessing the ocular ompA variants A, B, Ba and C are typically found wit
Externí odkaz:
https://doaj.org/article/4ae5540503384278b8c8d25e4cc25a61
Autor:
Ouli Xie, Cameron Zachreson, Gerry Tonkin-Hill, David J. Price, Jake A. Lacey, Jacqueline M. Morris, Malcolm I. McDonald, Asha C. Bowen, Philip M. Giffard, Bart J. Currie, Jonathan R. Carapetis, Deborah C. Holt, Stephen D. Bentley, Mark R. Davies, Steven Y. C. Tong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Streptococcus dysgalactiae subspecies equisimilis (SDSE) and Streptococcus pyogenes share skin and throat niches with extensive genomic homology and horizontal gene transfer (HGT) possibly underlying shared disease phenotypes. It is unknown
Externí odkaz:
https://doaj.org/article/42a9dffb6c3c4679a54672606334ce30
Autor:
Rebecca J Towers, Jonathan R Carapetis, Bart J Currie, Mark R Davies, Mark J Walker, Gordon Dougan, Philip M Giffard
Publikováno v:
PLoS ONE, Vol 8, Iss 9, p e73851 (2013)
The Indigenous population of the Northern Territory of Australia (NT) suffers from a very high burden of Streptococcus pyogenes disease, including cardiac and renal sequelae. The aim of this study was to determine if S. pyogenes isolated from this po
Externí odkaz:
https://doaj.org/article/6fb77e0c89014ade8e51025356e7a7e1
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33530 (2012)
Here we report a single nucleotide polymorphism (SNP) based genotyping method for Klebsiella pneumoniae utilising high-resolution melting (HRM) analysis of fragments within the multilocus sequence typing (MLST) loci. The approach is termed mini-MLST
Externí odkaz:
https://doaj.org/article/5936b9222b4f4a51949a87ca5ce3113a
Autor:
Steven Y C Tong, Farshid Dakh, Aeron C Hurt, Yi-Mo Deng, Kevin Freeman, Peter K Fagan, Ian G Barr, Philip M Giffard
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21446 (2011)
IntroductionWe aimed to design a real-time reverse-transcriptase-PCR (rRT-PCR), high-resolution melting (HRM) assay to detect the H275Y mutation that confers oseltamivir resistance in influenza A/H1N1 2009 viruses.FindingsA novel strategy of amplifyi
Externí odkaz:
https://doaj.org/article/6e5b1f5b85a949688f884df01347d8af
Autor:
Steven Y C Tong, Shirley Xie, Leisha J Richardson, Susan A Ballard, Farshid Dakh, Elizabeth A Grabsch, M Lindsay Grayson, Benjamin P Howden, Paul D R Johnson, Philip M Giffard
Publikováno v:
PLoS ONE, Vol 6, Iss 12, p e29189 (2011)
We have developed a single nucleotide polymorphism (SNP) nucleated high-resolution melting (HRM) technique to genotype Enterococcus faecium. Eight SNPs were derived from the E. faecium multilocus sequence typing (MLST) database and amplified fragment
Externí odkaz:
https://doaj.org/article/cc51d58b23ad42b1905eee8f1f4ea20d
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e19749 (2011)
High resolution melting (HRM) analysis is gaining prominence as a method for discriminating DNA sequence variants. Its advantage is that it is performed in a real-time PCR device, and the PCR amplification and HRM analysis are closed tube, and effect
Externí odkaz:
https://doaj.org/article/d04e2d54ccf644c0bc2a578d4d7ac913
Publikováno v:
PeerJ. 11:e15339
Here, we present the R package, minSNPs. This is a re-development of a previously described Java application named Minimum SNPs. MinSNPs assembles resolution-optimised sets of single nucleotide polymorphisms (SNPs) from sequence alignments such as ge
Autor:
M. Kalindu D. Rodrigo, Aarti Saiganesh, Andrew J. Hayes, Alisha M. Wilson, Jack Anstey, Janessa L. Pickering, Jua Iwasaki, Jessica Hillas, Scott Winslow, Tabitha Woodman, Philipp Nitschke, Jake A. Lacey, Karen J. Breese, Mark P. G. van der Linden, Philip M. Giffard, Steven Y. C. Tong, Nicola Gray, Keith A. Stubbs, Jonathan R. Carapetis, Asha C. Bowen, Mark R. Davies, Timothy C. Barnett
Publikováno v:
Nature Communications 13, 6557 (2022). doi:10.1038/s41467-022-34243-3
Nature Communications 13, 6557 (2022). doi:10.1038/s41467-022-34243-3
Published by Nature Publishing Group UK, [London]
Published by Nature Publishing Group UK, [London]
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2af6175c2d4b8c852d92435c501a1c40