Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Philip M, Cummins"'
Autor:
Daria S. Kostyunina, Simon C. Rowan, Nikolai V. Pakhomov, Eugene Dillon, Keith D. Rochfort, Philip M. Cummins, Malachy J. O’Rourke, Paul McLoughlin
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 68:551-565
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d45906ddf5d0822eb6c48ccd3004fb2
https://doi.org/10.1165/rcmb.2022-0340oc
https://doi.org/10.1165/rcmb.2022-0340oc
Autor:
Hannah Forde, Emma Harper, Keith D. Rochfort, Robert G. Wallace, Colin Davenport, Diarmuid Smith, Philip M. Cummins
Publikováno v:
Physiological Reports, Vol 8, Iss 20, Pp n/a-n/a (2020)
Abstract Studies suggest that tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) has vasoprotective potential, as low levels of TRAIL cause accelerated vascular calcification, whereas exogenous TRAIL administration exhibits anti‐at
Externí odkaz:
https://doaj.org/article/dcc46a8af909431bb702273bd7077131
Autor:
Bernard Degryse, Mishan Britto, Chun Xu Shan, Robert G. Wallace, Keith D. Rochfort, Philip M. Cummins, Gerardene Meade, Ronan P. Murphy
Publikováno v:
Data in Brief, Vol 15, Iss , Pp 600-605 (2017)
The data presented herein are connected to our research article (doi: 10.1016/j.biocel.2017.04.012) [1], in which we investigated the functional connections between the urokinase receptor (uPAR), and the ezrin/radixin/moesin (ERM) proteins, moesin an
Externí odkaz:
https://doaj.org/article/64876a7aaed64e9fade8a51955a55f97
Autor:
Emma Harper, Keith D Rochfort, Hannah Forde, Colin Davenport, Diarmuid Smith, Philip M Cummins
Publikováno v:
PLoS ONE, Vol 12, Iss 11, p e0188192 (2017)
Vascular calcification (VC) is a major risk factor for elevated cardiovascular morbidity/mortality. Underlying this process is osteoblastic signalling within the vessel wall involving complex and interlinked roles for receptor-activator of nuclear fa
Externí odkaz:
https://doaj.org/article/d61df034db9a47c5b33296e2285efef0
Autor:
Fiona A Martin, Alisha McLoughlin, Keith D Rochfort, Colin Davenport, Ronan P Murphy, Philip M Cummins
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e108254 (2014)
Background and objectivesThrombomodulin (TM), an integral membrane glycoprotein expressed on the lumenal surface of vascular endothelial cells, promotes anti-coagulant and anti-inflammatory properties. Release of functional TM from the endothelium su
Externí odkaz:
https://doaj.org/article/4dbe4fdfd97347e0bfe9271804d3ed15
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101815 (2014)
Blood-brain barrier (BBB) dysfunction is an integral feature of neurological disorders and involves the action of multiple proinflammatory cytokines on the microvascular endothelial cells lining cerebral capillaries. There is still however, considera
Externí odkaz:
https://doaj.org/article/0102f18804ab496c918377be783099cb
Autor:
Diarmuid Smith, Robert G. Wallace, Philip M. Cummins, Emma Harper, Hannah Forde, Keith D. Rochfort, Colin Davenport
Publikováno v:
Physiological Reports
Forde, Hannah ORCID: 0000-0001-7447-7264, Harper, Emma, Rochfort, Keith D. ORCID: 0000-0003-1198-5952 , Wallace, Robert G. ORCID: 0000-0002-1450-0634 , Davenport, Colin ORCID: 0000-0001-6854-6147 , Smith, Diarmuid and Cummins, Phil (2020) TRAIL inhibits oxidative stress in human aortic endothelial cells exposed to pro-inflammatory stimuli. Physiological Reports, 8 (20). ISSN 2051-817X
Physiological Reports, Vol 8, Iss 20, Pp n/a-n/a (2020)
Forde, Hannah ORCID: 0000-0001-7447-7264
Physiological Reports, Vol 8, Iss 20, Pp n/a-n/a (2020)
Studies suggest that tumor necrosis factor‐related apoptosis‐inducing ligand (TRAIL) has vasoprotective potential, as low levels of TRAIL cause accelerated vascular calcification, whereas exogenous TRAIL administration exhibits anti‐atheroscler
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b03ef47f58fc1c46e83037da0e5a8ac8
https://pubmed.ncbi.nlm.nih.gov/33080110
https://pubmed.ncbi.nlm.nih.gov/33080110
Publikováno v:
B59. HYPOXIA, OMICS, AND EPIGENETICS IN PULMONARY VASCULAR DISEASES AND RIGHT VENTRICULAR FAILURE.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bda273542623cdcbb7a9c4cdbd203736
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3879
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3879
Autor:
Hannah Forde, Philip M. Cummins, Diarmuid Smith, Emma Harper, Keith D. Rochfort, Colin Davenport
Publikováno v:
Cellular Signalling. 47:142-150
Background The intimal endothelium is known to condition the underlying medial smooth muscle cell (SMC) layer of the vessel wall, and is highly responsive to receptor-activator of nuclear factor-κB ligand (RANKL) and tumour necrosis factor-related a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b92707446b6ebf70e1949f9f614ed8e0
https://doi.org/10.1016/j.cellsig.2018.04.004
https://doi.org/10.1016/j.cellsig.2018.04.004
Autor:
Balamurali K. Ambati, Keith D. Rochfort, Peter Barabas, Robert G. Wallace, Philip M. Cummins, Tim M. Curtis, Hironori Uehara
Publikováno v:
Wallace, Robert G. ORCID: 0000-0002-1450-0634 , Rochfort, Keith D. ORCID: 0000-0003-1198-5952 , Barabas, Peter ORCID: 0000-0002-8166-3476 , Curtis, Timothy M., Uehara, Hironori ORCID: 0000-0001-6133-4918 , Ambati, Balamurali and Cummins, Phil (2021) COMP-Ang1: therapeutic potential of an engineered Angiopoietin-1 variant. Vascular Pharmacology, 141 . ISSN 1537-1891
The Angiopoietin-1/2 system is an opportune target for therapeutic intervention in a wide range of vascular pathologies, particularly through its association with endothelium. The complex multi-domain structure of native human Angiopoietin-1 has hind
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26802f1075f6e0e5e69c671a8296ce4f
https://doi.org/10.1016/j.vph.2021.106919
https://doi.org/10.1016/j.vph.2021.106919