Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Philip Lin Huang"'
Autor:
Norman R Watts, Elif Eren, Ira Palmer, Paul L Huang, Philip Lin Huang, Robert H Shoemaker, Sylvia Lee-Huang, Paul T Wingfield
Publikováno v:
PLoS ONE, Vol 18, Iss 6, p e0286370 (2023)
The continuing emergence of SARS-CoV-2 variants has highlighted the need to identify additional points for viral inhibition. Ribosome inactivating proteins (RIPs), such as MAP30 and Momordin which are derived from bitter melon (Momordica charantia),
Externí odkaz:
https://doaj.org/article/5d9e308f08a94ec1b1b3f9dcce79cce5
Publikováno v:
Journal of Clinical Medicine; Volume 10; Issue 4; Pages: 631
Journal of Clinical Medicine, Vol 10, Iss 631, p 631 (2021)
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 10, Iss 631, p 631 (2021)
Journal of Clinical Medicine
We carried out live-cell real-time fluorescence imaging to follow the effects of genetic (siRNA) knockdown (KD) of endothelial nitric oxide synthase (eNOS) on mitochondrial biogenesis and adipogenesis in human mesenchymal stem cells (hMSCs). We repor
Publikováno v:
Journal of pain and symptom management. 51(4)
Publikováno v:
The Open Conference Proceedings Journal. 1:81-86
Publikováno v:
Journal of Theoretical and Computational Chemistry. :471-485
A series of norbornane-based HIV-1 protease (PR) inhibitors are designed theoretically to displace the tetrahedrally coordinated internal water molecule that bridges inhibitor to flaps via hydrogen bonds. These designed inhibitors use the norbornenon
Publikováno v:
The Open Conference Proceedings Journal. 1:81-86
Diabetes, obesity, and the metabolic syndrome all increase the risk for cardiovascular disease. Epidemiologic studies have demonstrated that a Mediterranean diet rich in olive oil is associated with decrease in risk for cardiovascular disease, obesit
Autor:
Xiang-Peng Kong, Paul L. Huang, Yongtao Sun, John Z. H. Zhang, Dawei Zhang, Hao Chia Chen, Sylvia Lee-Huang, Huiguang Li, Philip Lin Huang
Publikováno v:
Biochemical and Biophysical Research Communications. 391:340-345
We report here the high-resolution atomic structures of GAP31 crystallized in the presence of HIV-LTR DNA oligonucleotides systematically designed to examine the adenosine glycosidase activity of this anti-HIV and anti-tumor plant protein. Structural
Autor:
Yun-Xing Wang, Jaison Jacob, Dennis A. Torchia, Paul T. Wemgfteld, Ira Palmer, Stephen J. Stahl, Joshua D. Kaufman, Philip Lin Huang, Paul Lee Huang, Sylvia Lee-Huang
Publikováno v:
Protein Science. 9:138-144
MAP30 is a 30 kDa single-stranded, type-I ribosome inactivating protein (RIP) possessing anti-tumor and anti-HIV activities. It binds both ribosomal RNA and the HIV-1 long-terminal repeat DNA. To understand the structural basis for MAP30 activities,
Publikováno v:
Journal of Theoretical and Computational Chemistry. :485-503
A series of HIV-1 protease (PR) inhibitors are designed to increase the binding affinity with PR subsites based on the quantum analysis of the contributions of molecular fragments in six FDA-approved PR drugs to the total binding interaction. The bin
Publikováno v:
AIDS research and human retroviruses. 30(11)
HIV-1 is capable of infecting target cells by both cell-free viral infection and cell-to-cell transmission.1 In cell-free viral infection, free virus is exposed to cellular, immunological, and drug barriers, so infection efficiency is low and drug se