Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Philip Lavere"'
Tributyltin chloride (TBT) induces RXRA down-regulation and lipid accumulation in human liver cells.
Autor:
Fabio Stossi, Radhika D Dandekar, Hannah Johnson, Philip Lavere, Charles E Foulds, Maureen G Mancini, Michael A Mancini
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224405 (2019)
A subset of environmental chemicals acts as "obesogens" as they increase adipose mass and lipid content in livers of treated rodents. One of the most studied class of obesogens are the tin-containing chemicals that have as a central moiety tributylti
Externí odkaz:
https://doaj.org/article/52b48cca01fc4bffb6206392385524b0
Autor:
PHILIP LAVERE, TIMOTHY E HOTZE
Publikováno v:
Chest. 162:A1799
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1efe46f2b364c98f6f0a9a38123772d0
https://doi.org/10.1016/j.chest.2022.08.1499
https://doi.org/10.1016/j.chest.2022.08.1499
Autor:
Yue Chen, Ze-Yi Zheng, Guo-Qiang Zhao, Beom-Jun Kim, Eric C. Chang, Jianheng Peng, Sinem Seker, Jiejun Shi, Jonathan T. Lei, Hilda Kennedy, Bing Zhang, Burcu Çakar, Doug W. Chan, Wei Song, Charles E. Foulds, Jing Li, Xiang Zhang, Jin Cao, Xin-Hui Du, Matthew J. Ellis, Purba Singh, Richard B. Lanman, Nhu-Chau Nguyen, Meenakshi Anurag, Kimberly C. Banks, Suhas Vasaikar, Xi Chen, Philip Lavere, Susan G. Hilsenbeck, Maryam Nemati Shafaee, Wei Li
Publikováno v:
Cancer Cell
We report that neurofibromin, a tumor suppressor and Ras-GAP (GTPase Activating Protein), is also an estrogen receptor-α (ER) transcriptional co-repressor through leucine/isoleucine-rich motifs that are functionally independent of GAP activity. GAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b996399f6ee1f8513ed83cf7c7d932
https://europepmc.org/articles/PMC7286719/
https://europepmc.org/articles/PMC7286719/
Publikováno v:
Chest. 160:A313
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a19cbe4a8822662e5da150666f0b82b
https://doi.org/10.1016/j.chest.2021.07.317
https://doi.org/10.1016/j.chest.2021.07.317
Autor:
Philip Lavere, Dharani Kumari Narendra
Publikováno v:
Chest
TOPIC: Chest Infections TYPE: Medical Student/Resident Case Reports INTRODUCTION: The presentation of fever, fatigue, myalgias, and acute hypoxemic respiratory failure is COVID-19 viral pneumonia until proven otherwise. However, findings like rash, p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce97dfefa3cfecc804f64ee4dd638ce0
http://europepmc.org/articles/PMC8503177
http://europepmc.org/articles/PMC8503177
Publikováno v:
Chest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f194e91e7fb2077dcfc4ff41dc062e6d
https://doi.org/10.1016/j.chest.2021.07.954
https://doi.org/10.1016/j.chest.2021.07.954
Autor:
Doug W. Chan, Charles E. Foulds, Burcu Çakar, M Kavuri, K Shah, Svasti Haricharan, Z-Y Zheng, Philip Lavere, J Yao, Jin Cao, Eric C. Chang, Meenakshi Anurag, David H. Gutmann, Purba Singh, Xian Chen, Joseph A. Toonen, MJ Ellis, Jonathan T. Lei
Publikováno v:
Cancer Research. 77:P1-08
Background. Although great strides have been made in targeting the ER pathway for treating ER+ breast cancer, relapse and death is common and is closely linked to resistance to ER-targeting agents. As a result, the majority of deaths from breast canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::159e3fd2af5b090de6621363b64577b5
https://doi.org/10.1158/1538-7445.sabcs16-p1-08-01
https://doi.org/10.1158/1538-7445.sabcs16-p1-08-01
Autor:
Philip Lavere, Michael A. Mancini, Radhika D. Dandekar, Hannah L. Johnson, Maureen G. Mancini, Fabio Stossi, Charles E. Foulds
Publikováno v:
PLoS ONE, Vol 14, Iss 11, p e0224405 (2019)
PLoS ONE
PLoS ONE
A subset of environmental chemicals acts as "obesogens" as they increase adipose mass and lipid content in livers of treated rodents. One of the most studied class of obesogens are the tin-containing chemicals that have as a central moiety tributylti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e86fb3a2118a191cf786f7b61d8e8a
https://doaj.org/article/52b48cca01fc4bffb6206392385524b0
https://doaj.org/article/52b48cca01fc4bffb6206392385524b0
Autor:
Yue Chen, Jun Qin, Anna Malovannaya, Shu-Ping Wang, Jieya Shao, Antrix Jain, Matthew J. Ellis, Jonathan T. Lei, Aarti D. Rohira, Guowei Gu, Robert G. Roeder, Jiangyong Shao, Charles E. Foulds, Suzanne A. W. Fuqua, Sung Yun Jung, Jin Wang, Shunqiang Li, Philip Lavere, David M. Lonard, David Edwards, Ross A. Hamilton, Yang Yu, Leah A. Gates, Ping Yi, Bert W. O'Malley
Publikováno v:
Oncogene
Approximately 75% of breast cancers are estrogen receptor alpha (ERα)-positive and are treatable with endocrine therapies, but often patients develop lethal resistant disease. Frequent mutations (10-40%) in the ligand-binding domain (LBD) codons in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e82ca89f3a25b8c13043c87d4c0421
https://pubmed.ncbi.nlm.nih.gov/29748621
https://pubmed.ncbi.nlm.nih.gov/29748621
Autor:
Xin-Hui Du, Tiffany Nguyen, Richarad B. Lanman, Philip Lavere, Meenakshi Anurag, Susan G. Hilsenbeck, Sinem Seker, Maryam Nemati Shafaee, Burcu Çakar, Jing Li, Kimberly C. Banks, Eric C. Chang, Xi Chen, Wei Song, Jin Gao, Doug W. Chan, Matthew J. Ellis, Purba Singh, Charles E. Foulds, Jianheng Peng, Ze-Yi Zheng, Jonathan T. Lei
Publikováno v:
Cancer Research. 78:1814-1814
NF1 has been best known as a GAP (GTPase Activating Protein) that inactivates Ras. However, we are now finding evidence that it also functions as an ER co-repressor, whose loss leads to endocrine therapy resistance. Sequencing tumor DNA from >600 ER+
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a53e459dfb11d03d0927f3301299f5d
https://doi.org/10.1158/1538-7445.am2018-1814
https://doi.org/10.1158/1538-7445.am2018-1814