Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Philip L. Stetson"'
Autor:
Joseph C. Kolars, Phyllissa Schmiedlin-Ren, Paul B. Watkins, Bob D. Rush, Philip L. Stetson, John J. Voorhees, Mary J. Ruwart, Elizabeth A. Duell
Publikováno v:
Transplantation. 53:596-601
Cyclosporine is converted to its major metabolites (M-17, M-1, and M-21) in human liver by enzymes belonging to the P450IIIA subfamily. These enzymes are also present in rat and human enterocytes; however, the possibility that CsA is metabolized in e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::14624067b5a4646a8a1fd1cdb93c9cc7
https://doi.org/10.1097/00007890-199203000-00021
https://doi.org/10.1097/00007890-199203000-00021
Autor:
Philip L. Stetson, Norma J. Johnson, Zhaomin Yang, James A. Knol, Patricia Terrio, William D. Ensminger, Daniel P. Normolle, Conrad A. Knutsen, Ermelinda Sakmar, Diane M. Prieskorn
Publikováno v:
JNCI Journal of the National Cancer Institute. 83:1659-1667
The thymidine analogues 5-bromo-2'-deoxyuridine (Brd-Urd) and 5-iodo-2'-deoxyuridine (IdUrd) compete with thymidine for incorporation into the DNA of replicating cells. This incorporation results in radiosensitizing effects which are directly related
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed231a628d2addda24e3efad614eee62
https://doi.org/10.1093/jnci/83.22.1659
https://doi.org/10.1093/jnci/83.22.1659
Autor:
Christine E. Dusenbury, David A. Shelton, Hong Wei Jing, Philip L. Stetson, William D. Ensminger, Eric C. Burton, Jonathan Maybaum
Publikováno v:
Biochemical Pharmacology. 42:131-137
Using a panel of four human colorectal tumor (HCT) cell lines, we have quantitatively characterized the incorporation of bromodeoxyuridine (BrdUrd) and iododeoxyuridine (IdUrd) into DNA, both as individual agents and in combination with fluoropyrimid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfb19a0f959ff39a6b185b94390b785b
https://doi.org/10.1016/0006-2952(91)90691-w
https://doi.org/10.1016/0006-2952(91)90691-w
Autor:
Philip L. Stetson, Jeannie B. Kirkpatrick, Motoki Shinohara, Christopher P. Chengelis, Daniel W. Sved, Nichole R. Myers
Publikováno v:
Reproductive toxicology (Elmsford, N.Y.). 27(3-4)
The toxicokinetics of perfluorohexanoic acid (PFHxA) and nonafluoro-1-butanesulfonic acid (PFBS) were evaluated in Sprague–Dawley rats and cynomolgus monkeys. Systemic exposure to PFHxA was lower than for PFBS following single equivalent intravenou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::962c6b313a622d296b49d46fb84007d5
https://pubmed.ncbi.nlm.nih.gov/19429410
https://pubmed.ncbi.nlm.nih.gov/19429410
Autor:
Scott D. Freer, Wei Bu, Philip L. Stetson, Daniel W. Sved, John B. Kurek, Robert A. Boyd, Shelly Hollar
Publikováno v:
Rapid communications in mass spectrometry : RCM. 17(21)
A liquid chromatography/mass spectrometry (LC/MS) analytical procedure, using a single column for sample clean-up, enrichment and separation, has been developed for the determination of the peptide AM336 in monkey cerebrospinal fluid (CSF). CSF sampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd29fac6982664d42b1f7d4801e493c3
https://pubmed.ncbi.nlm.nih.gov/14587085
https://pubmed.ncbi.nlm.nih.gov/14587085
Autor:
Tom O’Neill, Shelly Hollar, Wei Bu, Daniel W. Sved, Jane D. Mccarty, Philip L. Stetson, Nichole R. Myers
Publikováno v:
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 783(2)
A liquid chromatographic–tandem mass spectrometric (LC–MS–MS) method without sample pretreatment was developed and validated for determination of porphyrins in samples of canine urine. Acidified urine samples were directly injected into the LC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::468c62a01b835d50b7a4b729ef06c8d8
https://pubmed.ncbi.nlm.nih.gov/12482484
https://pubmed.ncbi.nlm.nih.gov/12482484
Autor:
Dragomir I. Draganov, Scott S. Billecke, Philip L. Stetson, Bert N. La Du, Catherine E. Watson
Publikováno v:
The Journal of biological chemistry. 275(43)
The paraoxonase gene family contains at least three members: PON1, PON2, and PON3. The physiological roles of the corresponding gene products are still uncertain. Until recently, only the serum paraoxonase/arylesterase (PON1) had been purified and ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e49519d63a9a5dd815759323e0a3fba6
https://pubmed.ncbi.nlm.nih.gov/10931838
https://pubmed.ncbi.nlm.nih.gov/10931838
Autor:
David Smith, Steven R. Cox, Carol A. Kauffman, Philip L. Stetson, Debbie S. Blake, Paul B. Watkins, Ching Ling Cheng, Gordon L. Amidon, Katherine M. Meyer, Peggy L. Carver
Publikováno v:
Clinical pharmacology and therapeutics. 61(5)
Objective The steady-state kinetics of delavirdine and desisopropyldelavirdine were evaluated in human immunodeficiency virus-positive patients after escalating oral doses and after repeated oral administrations at the same dose level. Study design P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d1ce0ef02ff186f55eae0bb8ff5cfa
https://pubmed.ncbi.nlm.nih.gov/9695728
https://pubmed.ncbi.nlm.nih.gov/9695728
Autor:
Theodore S. Lawrence, Jonathan Maybaum, William D. Ensminger, Mary A. Davis, Philip L. Stetson
Publikováno v:
International journal of radiation oncology, biology, physics. 18(6)
The influence of the duration of exposure to the halogenated pyrimidines iododeoxyuridine (IdUrd) and bromodeoxyuridine (BrdUrd) on incorporation into DNA and the resulting radiosensitization was studied in cultured human colon cancer cells. Cells we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52c6c52bf30674435ac30ee59c1b273b
https://pubmed.ncbi.nlm.nih.gov/2045313
https://pubmed.ncbi.nlm.nih.gov/2045313
Autor:
Theodore S. Lawrence, Emily Y. Chang, William D. Ensminger, Philip L. Stetson, Mary A. Davis, Daniel P. Normolle
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 27:243-244
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4428ac950ab405e50768340187296e6a
https://doi.org/10.1016/0360-3016(93)90818-g
https://doi.org/10.1016/0360-3016(93)90818-g