Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Philip L. Marshall"'
Autor:
Gregory C. Addicks, Hongbo Zhang, Dongryeol Ryu, Goutham Vasam, Alexander E. Green, Philip L. Marshall, Sonia Patel, Baeki E. Kang, Doyoun Kim, Elena Katsyuba, Evan G. Williams, Jean-Marc Renaud, Johan Auwerx, Keir J. Menzies
Publikováno v:
Journal of Cell Biology. 221
Protein lysine acetylation is a post-translational modification that regulates protein structure and function. It is targeted to proteins by lysine acetyltransferases (KATs) or removed by lysine deacetylases. This work identifies a role for the KAT e
Autor:
Hongbo Zhang, Alex E. Green, Patel S, Elena Katsyuba, Goutham Vasam, Doyoun Kim, Gregory C. Addicks, Evan G. Williams, Philip L. Marshall, Johan Auwerx, Dongryeol Ryu, Justin B. Renaud, Kang Be, Keir J. Menzies
This work identifies a novel role for the acetyltransferase GCN5 in regulating muscle integrity through inhibition of DNA binding activity of the transcriptional repressor YY1. Here we report that in mice a muscle-specific knockout of GCN5 (Gcn5skm-/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::551139f6f98f27f2b66c513b2cde76eb
https://doi.org/10.1101/2021.03.29.436986
https://doi.org/10.1101/2021.03.29.436986
Autor:
Lara Gharibeh, David A. Patten, John P. Veinot, Philip L. Marshall, Bianca Ichim, Wael Maharsy, Keir J. Menzies, Arkadiy Reunov, Mary-Ellen Harper, Mona Nemer, Jian Ying Xuan, Georges N. Kanaan
Publikováno v:
Redox Biology, Vol 14, Iss, Pp 509-521 (2018)
Redox Biology
Redox Biology
Glutaredoxin 2 (GRX2), a mitochondrial glutathione-dependent oxidoreductase, is central to glutathione homeostasis and mitochondrial redox, which is crucial in highly metabolic tissues like the heart. Previous research showed that absence of Grx2, le