Výsledky vyhledávání - "Philip L. Cimo"

Inhibition of ristocetin-induced platelet agglutination by vancomycin

Autor: P. Roper, Joel L. Moake, Philip L. Cimo, Ethan A. Natelson, D. M. Peterson

Publikováno v: Blood. 50:397-406

Ristocetin and vancomycin are structurally similar glycopeptide antibiotics. Both vancomycin and ristocetin in high concentrations (3.0 mg/ml) cause the precipitation of fibrinogen, plasminogen, and IgG from platelet-poor plasma (PPP). In contrast to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b59683383ae591ea3812706b901bbd7b
https://doi.org/10.1182/blood.v50.3.397.bloodjournal503397

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Differential Effects of Cytochalasin B on Platelet Release, Aggregation and Contractility: Evidence against a Contractile Mechanism for the Release of Platelet Granular Contents

Autor: Joel L. Moake, Philip L. Cimo, Larry V. McIntire, John P. Kirkpatrick

Publikováno v: Thrombosis and Haemostasis. 42:1483-1489

SummaryCytochalasin B alters the structure and functional properties of filamentous actin. Platelet-mediated clot retraction in dilute platelet-rich plasma (PRP) is inhibited progressively at cytochalasin B concentrations of 0.01 mg/ml, 0.05 mg/ml an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::42cc2facd2e4c1c2123553d76ed97cf3
https://doi.org/10.1055/s-0038-1657049

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Posttransfusion purpura: Therapeutic failure of PlAl-negative platelet transfusion

Autor: Philip L. Cimo, James B. Gerstner, Richard H. Aster, Martin J. Smith, Kent Davis

Publikováno v: American Journal of Hematology. 6:71-75

The effect of platelet type-specific transfusion in posttranfusion purpura is reported. Seven days after receiving 4 units of whole blood during total hip replacement a 69-year-old woman developed fulminant thrombocytopenic purpura. Her undiluted ser

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de4e2be0baac16bbc64103877e85d0e
https://doi.org/10.1002/ajh.2830060110

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Inherited combined deficiency of factor V and factor VIII: Report of a case with normal factor VIII antigen and ristocetin-induced platelet aggregation

Autor: Ethan A. Natelson, Joel L. Moake, K. R. Fox, M. F. Gonzalez, Philip L. Cimo

Publikováno v: American Journal of Hematology. 2:385-391

A patient with inherited combined deficiency of factor V and factor VIII is reported, who demonstrated normal levels of factor VIII antigen and plasma cofactor for ristocetin-induced platelet aggregation. The relationship of this condition to classic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76534b890fc80ce5d9a1ccfece40df7
https://doi.org/10.1002/ajh.2830020408

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A clinical trial of adriamycin in the malignant lymphomas

Autor: Darrell Hensleigh, Philip L. Cimo, Richard A. Rudders

Publikováno v: Cancer. 34:1571-1575

Adriamycin was administered to 14 patients with far-advanced malignant lymphoma. Objective responses were seen only in those patients who were able to tolerate a complete course of therapy, and included two patients with histiocytic lymphoma and thre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9dbe53d581adcdbc3a7b3ef1dfebbbad
https://doi.org/10.1002/1097-0142(197411)34:5<1571::aid-cncr2820340502>3.0.co

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Fibrinogen houston: A dysfibrinogen exhibiting defective fibrin monomer aggregation and α-chain cross-linkages

Autor: Charles L. Conlon, Ronald S. Weinger, Philip L. Cimo, Christine Rudy, Joel L. Moake

Publikováno v: American Journal of Hematology. 9:237-248

A 38-year-old male patient with a life-long history of easy bruising and mild bleeding had a prolonged activated partial thromboplastin time (APTT), prothrombin time (PT), and thrombin time (TT). Reptilase (Bathrops atrox) clotting time was normal. H

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83ccbfaf394ae1a515ef7cb7ed8a671c
https://doi.org/10.1002/ajh.2830090302

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Effects of Prostaglandins, Derivatives of Cyclic 3':5'-AMP, Theophylline, Cholinergic Agents and Colchicine on Clot Retraction in Dilute Platelet-Rich Plasma and Gel-Separated Platelet Test Systems

Autor: Philip L. Cimo, D. M. Peterson, K Widmer, Joel L. Moake, J R Gum

Publikováno v: Thrombosis and Haemostasis. 38:0420-0428

SummaryIn dilute suspensions of platelet-rich plasma (PRP) or gel-separated platelets (GSP), dibutyryl-cAMP (DBcAMP) and monobutyryl-cAMP inhibited platelet-mediated fibrin clot retraction in concentrations of 2–3 × 10–6M, with complete inhibiti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6cfa972d50dc9b8afb12a22a7771d7df
https://doi.org/10.1055/s-0038-1651477

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AET-treated platelets: their usefulness for platelet antibody detection and an examination of their altered sensitivity to immune lysis

Autor: Philip L. Cimo, Susan A. Gerber

Publikováno v: Blood. 54:1101-1108

2-Aminoethylisothiouronium bromide (AET) increases the sensitivity of blood cells to complement-mediated immune lysis. We compared the sensitivities of untreated or AET-treated platelets to immune lysis induced by different types of platelet antibody

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::df691add6752df939811754ae9eaa7dd
https://doi.org/10.1182/blood.v54.5.1101.1101

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Post-Transfusion Purpura

Autor: Richard H. Aster, Philip L. Cimo

Publikováno v: New England Journal of Medicine. 287:290-292

POST-TRANSFUSION purpura (PTP) is a rare but well defined syndrome first characterized by Shulman et al.1 as a severe megakaryocytic thrombocytopenic purpura developing one week after blood transfusion. In each case a platelet isoantibody has been pr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ae8bc57fc74418249959bf1a4d64a9e
https://doi.org/10.1056/nejm197208102870608

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