Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Philip Konietzke"'
Autor:
Philip Konietzke, Christian Brunner, Marilisa Konietzke, Willi Linus Wagner, Oliver Weinheimer, Claus Peter Heußel, Felix J. F. Herth, Franziska Trudzinski, Hans-Ulrich Kauczor, Mark Oliver Wielpütz
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
BackgroundIn chronic obstructive pulmonary disease (COPD) abnormal lung function is related to emphysema and airway obstruction, but their relative contribution in each GOLD-stage is not fully understood. In this study, we used quantitative computed
Externí odkaz:
https://doaj.org/article/6e78cf98244e45d4b8227c9ac1853d8e
Autor:
Oliver Weinheimer, Philip Konietzke, Willi L. Wagner, Dorothea Weber, Beverly Newman, Craig J. Galbán, Hans-Ulrich Kauczor, Marcus A. Mall, Terry E. Robinson, Mark O. Wielpütz
Publikováno v:
Frontiers in Pediatrics, Vol 11 (2023)
ObjectivesQuantitative computed tomography (QCT) offers some promising markers to quantify cystic fibrosis (CF)-lung disease. Air trapping may precede irreversible bronchiectasis; therefore, the temporal interdependencies of functional and structural
Externí odkaz:
https://doaj.org/article/449af3d86b7140669ed3c77f9323ce8f
Autor:
Julia Duerr, Dominik H. W. Leitz, Magdalena Szczygiel, Dmytro Dvornikov, Simon G. Fraumann, Clemens Kreutz, Piotr K. Zadora, Ayça Seyhan Agircan, Philip Konietzke, Theresa A. Engelmann, Jan Hegermann, Surafel Mulugeta, Hiroshi Kawabe, Lars Knudsen, Matthias Ochs, Daniela Rotin, Thomas Muley, Michael Kreuter, Felix J. F. Herth, Mark O. Wielpütz, Michael F. Beers, Ursula Klingmüller, Marcus A. Mall
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Idiopathic pulmonary fibrosis (IPF) is a devastating disease with poor prognosis. Here, the authors show that deficiency of the E3 ubiqutin-protein ligase Nedd4-2 in airway epithelial cells causes IPF-like disease in adult mice. This model may aid st
Externí odkaz:
https://doaj.org/article/ae55c88d44b14c0496555b2c7a52b8da
Autor:
Philip Konietzke, Hauke H. Steentoft, Willi L. Wagner, Jonas Albers, Christian Dullin, Stephan Skornitzke, Wolfram Stiller, Tim F. Weber, Hans-Ulrich Kauczor, Mark O. Wielpütz
Publikováno v:
Heliyon, Vol 7, Iss 5, Pp e07066- (2021)
Objectives: To investigate the value of spectral-detector computed tomography (SDCT) parameters for the quantitative differentiation between atelectasis and pneumonia on contrast-enhanced chest CT. Material and methods: Sixty-three patients, 22 clini
Externí odkaz:
https://doaj.org/article/99e108a12c13422a87128d8a2458bace
Autor:
Philip Konietzke, Jan Mueller, Felix Wuennemann, Willi L Wagner, Jens-Peter Schenk, Abdulsattar Alrajab, Hans-Ulrich Kauczor, Mirjam Stahl, Marcus A Mall, Mark O Wielpütz, Olaf Sommerburg
Publikováno v:
PLoS ONE, Vol 15, Iss 3, p e0230252 (2020)
INTRODUCTION:In children with pneumonia, chest x-ray (CXR) is typically the first imaging modality used for diagnostic work-up. Repeated CXR or computed tomography (CT) are often necessary if complications such as abscesses or empyema arise, thus inc
Externí odkaz:
https://doaj.org/article/d3f960fa824744328df79df46f0f6bfc
Autor:
Philip Konietzke, Oliver Weinheimer, Willi L Wagner, Felix Wuennemann, Christian Hintze, Juergen Biederer, Claus P Heussel, Hans-Ulrich Kauczor, Mark O Wielpütz
Publikováno v:
PLoS ONE, Vol 15, Iss 8, p e0237939 (2020)
IntroductionQuantitative analysis of multi-detector computed tomography (MDCT) plays an increasingly important role in assessing airway disease. Depending on the algorithms used, airway dimensions may be over- or underestimated, primarily if contrast
Externí odkaz:
https://doaj.org/article/9cc5530884544f0aad38592764a45cfe
Autor:
Willi L Wagner, Yifan Zheng, Aidan Pierce, Maximilian Ackermann, Heinz Horstmann, Thomas Kuner, Paolo Ronchi, Yannick Schwab, Philip Konietzke, Felix Wünnemann, Mark O Wielpütz, Hans-Ulrich Kauczor, Steven J Mentzer
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0238798 (2020)
The mesothelium is a dynamic and specialized tissue layer that covers the somatic cavities (pleural, peritoneal, and pericardial) as well as the surface of the visceral organs such as the lung, heart, liver, bowel and tunica vaginalis testis. The pot
Externí odkaz:
https://doaj.org/article/6da76f6207b6498d9b308fdb13a22005
Autor:
Philip Konietzke, Oliver Weinheimer, Mark O Wielpütz, Dasha Savage, Tiglath Ziyeh, Christin Tu, Beverly Newman, Craig J Galbán, Marcus A Mall, Hans-Ulrich Kauczor, Terry E Robinson
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0194557 (2018)
Densitometry on paired inspiratory and expiratory multidetector computed tomography (MDCT) for the quantification of air trapping is an important approach to assess functional changes in airways diseases such as cystic fibrosis (CF). For a regional a
Externí odkaz:
https://doaj.org/article/91c1aede7c4e4fbdbce2b16532fcf965
Autor:
Arndt Lukas Bodenberger, Philip Konietzke, Oliver Weinheimer, Willi Linus Wagner, Wolfram Stiller, Tim Frederik Weber, Claus Peter Heussel, Hans-Ulrich Kauczor, Mark Oliver Wielpütz
Publikováno v:
European Radiology.
Objectives Quantitative computed tomography (CT) plays an increasingly important role in phenotyping airway diseases. Lung parenchyma and airway inflammation could be quantified by contrast enhancement at CT, but its investigation by multiphasic exam
Autor:
Frank Risse, Marilisa Schiwek, Philip Konietzke, Jürgen Biederer, Oyunbileg von Stackelberg, Simon M. F. Triphan, Oliver Weinheimer, Monika Eichinger, Bertram J. Jobst, Mark O. Wielpütz, Rudolf A. Jörres, Claus Vogelmeier, Claus Peter Heußel, Hans-Ulrich Kauczor
Publikováno v:
European Radiology. 32:1879-1890
Objectives Pulmonary perfusion abnormalities are prevalent in patients with chronic obstructive pulmonary disease (COPD), are potentially reversible, and may be associated with emphysema development. Therefore, we aimed to evaluate the clinical meani