Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Philip Kitchen"'
Autor:
Jonas Hyld Steffen, Julie Winkel Missel, Tamim Al-Jubair, Philip Kitchen, Mootaz M. Salman, Roslyn M. Bill, Susanna Törnroth-Horsefield, Pontus Gourdon
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101312- (2022)
Summary: Aquaporins (AQPs) are water channels embedded in the cell membrane that are critical in maintaining water homeostasis. We describe a protocol for determining the water permeation capacity of AQPs reconstituted into proteoliposomes. Using a s
Externí odkaz:
https://doaj.org/article/1a3eb367bcee4d1c9d47e268d3434edd
Autor:
Tamim Al-Jubair, Jonas Hyld Steffen, Julie Winkel Missel, Philip Kitchen, Mootaz M. Salman, Roslyn M. Bill, Pontus Gourdon, Susanna Törnroth-Horsefield
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101298- (2022)
Summary: Aquaporins (AQPs) are membrane-bound water channels that play crucial roles in maintaining the water homeostasis of the human body. Here, we present a protocol for high-yield recombinant expression of human AQPs in the methylotropic yeast Pi
Externí odkaz:
https://doaj.org/article/5ab3c0de13584bbd895ba84cf305b169
Autor:
Tamim Al-Jubair, Jonas Hyld Steffen, Julie Winkel Missel, Philip Kitchen, Mootaz M. Salman, Roslyn M. Bill, Pontus Gourdon, Susanna Törnroth-Horsefield
Publikováno v:
STAR Protocols, Vol 3, Iss 2, Pp 101316- (2022)
Summary: Aquaporin water channels (AQPs) are membrane proteins that maintain cellular water homeostasis. The interactions between human AQPs and other proteins play crucial roles in AQP regulation by both gating and trafficking. Here, we describe a p
Externí odkaz:
https://doaj.org/article/cd7e6ed9d36d4404b5a0e95d3eb6b738
Autor:
Philip Kitchen, Mootaz M. Salman, Mohammed Abir-Awan, Tamim Al-Jubair, Susanna Törnroth- Horsefield, Alex C. Conner, Roslyn M. Bill
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100157- (2020)
Summary: Aquaporins (AQPs) are membrane channel proteins that facilitate the movement of water down osmotic gradients across biological membranes. This protocol allows measurements of AQP-mediated water transport across the plasma membrane of live ma
Externí odkaz:
https://doaj.org/article/09f4c22380c54f5eb2674a12b11cd820
Autor:
Philip Kitchen, Marwa E. Tourky
Publikováno v:
Revista de Estudios Empresariales. Segunda Época, Iss 2 (2020)
Integrated marketing communications (IMC) are a core part of business success in the 21st century, but are facing exceptional challenges, some of which predate the devastation wrought by the COVID-19 pandemic. The various stages of IMC offer rich pot
Externí odkaz:
https://doaj.org/article/14c8c243d6cd43a3bce8ba3b80cc4614
Autor:
Sébastien Gauvrit, Alethia Villasenor, Boris Strilic, Philip Kitchen, Michelle M. Collins, Rubén Marín-Juez, Stefan Guenther, Hans-Martin Maischein, Nana Fukuda, Maurice A. Canham, Joshua M. Brickman, Clifford W. Bogue, Padma-Sheela Jayaraman, Didier Y. R. Stainier
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-14 (2018)
VEGFC, its receptor FLT4, and transcriptional effector PROX1 control formation of the lymphatic system but how is unclear. Here, the authors show that the transcription factor hematopoietically expressed homeobox (HHEX) regulates VEGFC, FLT4 and PROX
Externí odkaz:
https://doaj.org/article/3601d02f4c94462c8cb4148709279b67
Autor:
Mootaz M. Salman, Philip Kitchen, M. Nicola Woodroofe, Roslyn M. Bill, Alex C. Conner, Paul R. Heath, Matthew T. Conner
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 11 (2017)
Hypothermia is increasingly used as a therapeutic measure to treat brain injury. However, the cellular mechanisms underpinning its actions are complex and are not yet fully elucidated. Astrocytes are the most abundant cell type in the brain and are l
Externí odkaz:
https://doaj.org/article/c8691420063745908904d0e3c1ebc902
Autor:
Philip Kitchen, Fredrik Öberg, Jennie Sjöhamn, Kristina Hedfalk, Roslyn M Bill, Alex C Conner, Matthew T Conner, Susanna Törnroth-Horsefield
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143027 (2015)
Aquaporin membrane protein channels mediate cellular water flow. Human aquaporin 5 (AQP5) is highly expressed in the respiratory system and secretory glands where it facilitates the osmotically-driven generation of pulmonary secretions, saliva, sweat
Externí odkaz:
https://doaj.org/article/999e92a6256e47d0a85df8d89f6d84c8
Autor:
Emma M J Passchier, Sven Kerst, Eelke Brouwers, Eline M C Hamilton, Quinty Bisseling, Marianna Bugiani, Quinten Waisfisz, Philip Kitchen, Lucas Unger, Marjolein Breur, Leoni Hoogterp, Sharon I de Vries, Truus E M Abbink, Maarten H P Kole, Rob Leurs, Henry F Vischer, Maria S Brignone, Elena Ambrosini, François Feillet, Alfred P Born, Leon G Epstein, Huibert D Mansvelder, Rogier Min, Marjo S van der Knaap
Publikováno v:
Brain. Oxford University Press
Brain oedema is a life-threatening complication of various neurological conditions. Understanding molecular mechanisms of brain volume regulation is critical for therapy development. Unique insight comes from monogenic diseases characterized by chron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ab8f0d13111ae7eb9457056d03141c
https://doi.org/10.1093/brain/awad146
https://doi.org/10.1093/brain/awad146
Autor:
Padma-Sheela Jayaraman, Kevin Gaston, Simon Afford, Sebastian Oltean, Jutamaad Satayavivad, Anyaporn Sawasdichai, Jomnarong Lertsuwan, Nikki Lau, Danielle Clark, Ka Ying Lee, Philip Kitchen
Fig.S1 effects of PRH KD Fig.S2 effects of PRH OE Fig.S3 Gene expression and gene ontology Fig.S4 Heat maps Fig.S5 ChIP sequencing Fig.S6 Dose response curves Fig. S7 Western blotting Rb expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f31c8cfadb259889931d354c066cc5a
https://doi.org/10.1158/0008-5472.22424173.v1
https://doi.org/10.1158/0008-5472.22424173.v1
