Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Philip Jeffrey"'
Autor:
Saxon, Philip Jeffrey
Publikováno v:
In English for Specific Purposes October 2023 72:1-3
Publikováno v:
J Am Chem Soc
The dialkyl-ortho-biaryl class of phosphines, commonly known as Buchwald-type ligands, are among the most important phosphines in Pd-catalyzed cross-coupling catalysis. These ligands have also been successfully applied to several synthetically valuab
Publikováno v:
Day 3 Wed, May 03, 2023.
Two historical voyages were completed in December 2021 and January 2022 over the Northern Sea Route (NSR) in a westerly direction. A lack of accurate real time data regarding ice conditions and the influence of changing meteorological conditions seve
Autor:
Stefan Knapp, Jürg Schwaller, Rab Prinjha, Tony Kouzarides, Nicholas B. La Thangue, Marjeta Urh, Danette L. Daniels, Duncan Hay, Susanne Müller, Sharlene Velichko, Alison O'Mahony, Paul E. Brennan, Chas Bountra, Matteo L. Vecellio, Simon Taylor, Philip Jeffrey, Dave Lugo, Kevin Lee, Nigel Parr, Umesh Kumar, Samuel Robson, Andrew Bannister, Ka Hing Che, Christopher Wells, Clarence Yapp, Panagis Filippakopoulos, Anthony Tumber, Martin Philpott, Sarah Martin, Octovia Monteiro, Heidi Olzscha, Julia Meier, Katherine Jones, Katharina Leonards, Angeliki Thanasopoulou, Oleg Fedorov, Sarah Picaud
Description of additional methods and procedures used in the study. Also includes Supplemental References.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57235f2b6dacb19e5e6c1bbf5652d40c
https://doi.org/10.1158/0008-5472.22406324
https://doi.org/10.1158/0008-5472.22406324
Autor:
Stefan Knapp, Jürg Schwaller, Rab Prinjha, Tony Kouzarides, Nicholas B. La Thangue, Marjeta Urh, Danette L. Daniels, Duncan Hay, Susanne Müller, Sharlene Velichko, Alison O'Mahony, Paul E. Brennan, Chas Bountra, Matteo L. Vecellio, Simon Taylor, Philip Jeffrey, Dave Lugo, Kevin Lee, Nigel Parr, Umesh Kumar, Samuel Robson, Andrew Bannister, Ka Hing Che, Christopher Wells, Clarence Yapp, Panagis Filippakopoulos, Anthony Tumber, Martin Philpott, Sarah Martin, Octovia Monteiro, Heidi Olzscha, Julia Meier, Katherine Jones, Katharina Leonards, Angeliki Thanasopoulou, Oleg Fedorov, Sarah Picaud
The histone acetyltransferases CBP/p300 are involved in recurrent leukemia-associated chromosomal translocations and are key regulators of cell growth. Therefore, efforts to generate inhibitors of CBP/p300 are of clinical value. We developed a specif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40435e054abe8c3438258da01486a385
https://doi.org/10.1158/0008-5472.c.6507044
https://doi.org/10.1158/0008-5472.c.6507044
Autor:
Stefan Knapp, Jürg Schwaller, Rab Prinjha, Tony Kouzarides, Nicholas B. La Thangue, Marjeta Urh, Danette L. Daniels, Duncan Hay, Susanne Müller, Sharlene Velichko, Alison O'Mahony, Paul E. Brennan, Chas Bountra, Matteo L. Vecellio, Simon Taylor, Philip Jeffrey, Dave Lugo, Kevin Lee, Nigel Parr, Umesh Kumar, Samuel Robson, Andrew Bannister, Ka Hing Che, Christopher Wells, Clarence Yapp, Panagis Filippakopoulos, Anthony Tumber, Martin Philpott, Sarah Martin, Octovia Monteiro, Heidi Olzscha, Julia Meier, Katherine Jones, Katharina Leonards, Angeliki Thanasopoulou, Oleg Fedorov, Sarah Picaud
BLI evaluation of I-CBP112 selectivity (S1); BioMAP data for I-CBP112 (S2); Effects on MLL-AF9 and NUP98-HOXA9 (S3); Immunophenotype of injected MLL-AF9 cells (S4); Cell survival data (S5); Synergy with JQ1 and doxorubicin (S6).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7179d3022dddf0f23baaefb469c32d18
https://doi.org/10.1158/0008-5472.22406327.v1
https://doi.org/10.1158/0008-5472.22406327.v1
Autor:
Stefan Knapp, Jürg Schwaller, Rab Prinjha, Tony Kouzarides, Nicholas B. La Thangue, Marjeta Urh, Danette L. Daniels, Duncan Hay, Susanne Müller, Sharlene Velichko, Alison O'Mahony, Paul E. Brennan, Chas Bountra, Matteo L. Vecellio, Simon Taylor, Philip Jeffrey, Dave Lugo, Kevin Lee, Nigel Parr, Umesh Kumar, Samuel Robson, Andrew Bannister, Ka Hing Che, Christopher Wells, Clarence Yapp, Panagis Filippakopoulos, Anthony Tumber, Martin Philpott, Sarah Martin, Octovia Monteiro, Heidi Olzscha, Julia Meier, Katherine Jones, Katharina Leonards, Angeliki Thanasopoulou, Oleg Fedorov, Sarah Picaud
I-CBP112 ΔTm data for bromodomains (S1); I-CBP112 ITC data (S2); Selectivity screening data outside BRD family (S3); ITC data (S4); Data collection and refinement statistics (S5); I-CBP112 deregulated genes 3d KASUMI-1 (S6); I-CBP112 deregulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1968754395c665786341968851738032
https://doi.org/10.1158/0008-5472.22406321
https://doi.org/10.1158/0008-5472.22406321
The dialkyl-ortho-biaryl class of phosphines, commonly known as Buchwald-type ligands, are among the most important phosphines in Pd-catalyzed cross-coupling catalysis. These ligands have also recently been applied to select Ni-catalyzed cross-coupli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::202f92e21dcf8cff4e23ff19a2f1a97f
https://doi.org/10.26434/chemrxiv-2022-ck2ll
https://doi.org/10.26434/chemrxiv-2022-ck2ll
Autor:
Clare E Ryan, Kelechi Ugonna, Fiona Shackley, Stephen Owens, Philip Jeffrey Brown, Chinenye I Ilozue, Penelope K. Ellis, Andrew Riordan, David Hughes, Sarah Rowland-Jones, Paul Collini
Publikováno v:
Pediatric Infectious Disease Journal. 39:1103-1105
Chronic lung disease (CLD) is common in individuals living with perinatally acquired HIV (PA-HIV) in southern/eastern Africa. Most of the UK PA-HIV population are African. We conducted a case-note review of CLD in 3 UK PA-HIV cohorts (n = 98). Bronch