Zobrazeno 1 - 10
of 34
pro vyhledávání: '"Philip J.B. Koeck"'
Autor:
Nina Kronqvist, Jan Johansson, Sameer Hassan, Xueying Zhong, Anna Rising, Hans Hebert, André Fisahn, Gefei Chen, Axel Abelein, Philip J.B. Koeck, Henrik Biverstål, Yuniesky Andrade-Talavera, Helen Poska, Axel Leppert
Proteins can self-assemble into amyloid fibrils or amorphous aggregates and thereby cause disease. Molecular chaperones can prevent both these types of protein aggregation, but the respective mechanisms are not fully understood. The BRICHOS domain co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::27a43bde0ddd13c261d2e5a09cb42d6c
https://doi.org/10.1101/2021.12.01.470723
https://doi.org/10.1101/2021.12.01.470723
Autor:
Philip J.B. Koeck
Publikováno v:
Ultramicroscopy. 205:62-69
Autor:
Margit Kaldmäe, Thibault Vosselman, Xueying Zhong, Dilraj Lama, Gefei Chen, Mihkel Saluri, Nina Kronqvist, Jia Wei Siau, Aik Seng Ng, Farid J. Ghadessy, Pierre Sabatier, Borivoj Vojtesek, Médoune Sarr, Cagla Sahin, Nicklas Österlund, Leopold L. Ilag, Venla A. Väänänen, Saikiran Sedimbi, Marie Arsenian-Henriksson, Roman A. Zubarev, Lennart Nilsson, Philip J.B. Koeck, Anna Rising, Axel Abelein, Nicolas Fritz, Jan Johansson, David P. Lane, Michael Landreh
Publikováno v:
Structure. 30:733-742.e7
Disordered proteins pose a major challenge to structural biology. A prominent example is the tumor suppressor p53, whose low expression levels and poor conformational stability hamper the development of cancer therapeutics. All these characteristics
Autor:
Farid J. Ghadessy, Roman A. Zubarev, Anna Rising, Lennart Nilsson, Gefei Chen, Philip J.B. Koeck, Nicolas Fritz, Thibault Vosselman, David P. Lane, Michael Landreh, Leopold L. Ilag, Pierre Sabatier, Aik Seng Ng, Jan Johansson, Saikiran K. Sedimbi, Venla A. Väänänen, Jia Wei Siau, Xueying Zhong, Médoune Sarr, Margit Kaldmäe, Borivoj Vojtesek, Nina Kronqvist, Mihkel Saluri, Dilraj Lama, Nicklas Österlund, Cagla Sahin
Protein disorder is a major hurdle for structural biology. A prominent example is the tumour suppressor p53, whose low expression levels and poor conformational stability due to a high degree of disorder pose major challenges to the development of ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec1032525eb1410efe687fc4f9fe084d
https://doi.org/10.1101/2021.02.22.432221
https://doi.org/10.1101/2021.02.22.432221
Autor:
David P. Lane, Nicolas Fritz, Margit Kaldmäe, Farid J. Ghadessy, Jia Wei Sau, Philip J.B. Koeck, Roman A. Zubarev, Anna Rising, Axel Abelein, Michael Landreh, Xueying Zhong, Thibault Vosselman, Marie Arsenain-Henriksson, Mihkel Saluri, Médoune Sarr, Gefei Chen, Lennart Nilsson, Venla A. Väänänen, Pierre Sabatier, Saikiran K. Sedimbi, Borivoj Vojtesek, Nicklas Österlund, Cagla Sahin, Jan Johansson, Dilraj Lama, Leopold L. Ilag, Aik Seng Ng, Nina Kronqvist
Publikováno v:
SSRN Electronic Journal.
Disordered proteins pose a major challenge to structural biology. A prominent example is the tumour suppressor p53, whose low expression levels and poor conformational stability due to a high degree of disorder hamper the development of cancer therap
Autor:
Philip J.B. Koeck
Publikováno v:
Ultramicroscopy. 182:81-84
• A novel design for a single side band aperture is presented, which allows determining defocus and astigmatism from the recorded images.
Autor:
Philip J.B. Koeck
Publikováno v:
Ultramicroscopy. 154:37-41
Hilbert phase contrast has been recognized as a means of recording high resolution images with high contrast using a transmission electron microscope. This imaging mode could be used to image typical phase objects such as unstained biological molecul
Autor:
Philip J.B. Koeck, A. Karshikoff
Publikováno v:
Journal of Microscopy. 259:197-209
Summary We establish expressions for the linear and quadratic terms in the series expansion of the phase and the phase and amplitude object description of imaging thin specimens by transmission electron microscopy. Based on these expressions we simul
Autor:
Philip J.B. Koeck
Publikováno v:
Journal of Microscopy. 259:74-78
Summary Zernike phase contrast has been recognized as a means of recording high-resolution images with high contrast using a transmission electron microscope. This imaging mode can be used to image typical phase objects such as unstained biological m
Publikováno v:
Structure. 23:199-205
SummaryThe ligand-gated potassium channels are stimulated by various kinds of messengers. Previous studies showed that ligand-gated potassium channels containing RCK domains (the regulator of the conductance of potassium ion) form a dimer of tetramer