Zobrazeno 1 - 10
of 85
pro vyhledávání: '"Philip J. Richter"'
Publikováno v:
Journal of the American Association for Laboratory Animal Science : JAALAS, vol 58, iss 5
Gnotobiotic animal research has expanded markedly over the past decade. Although germ-free animals were first described more than 100 y ago, little evidence-based guidance is available on best operational procedures. A key aspect of gnotobiotic techn
Autor:
Kent G. Osborn, James C. Eisenach, Marjorie R. Grafe, Philip J. Richter, Shotaro Hobo, Tony L. Yaksh, Christopher M. Peters, Steven S. Rossi
Publikováno v:
Anesthesiology. 120:951-961
BackgroundAnatomic, physiologic, and behavioral studies in animals suggest that spinally released oxytocin should produce analgesia in humans and may also protect from chronic pain after injury. In this article, the authors report preclinical toxicit
Publikováno v:
Drug Discovery Today: Disease Models. 28:1-2
Autor:
Kent G. Osborn, Samantha L. Veesart, Mark T. Butt, Philip J. Richter, Denise Higgins, Tony L. Yaksh, Shelle Malkmus, Douglas A. Lappi, Michael Rathbun, Qinghao Xu, Joanne Steinauer, Ashley J. Wiese, Brian J. Russell
Publikováno v:
Anesthesiology. 119:1163-1177
Background:Neurokinin-1 receptors (NK1-rs) located on superficial dorsal horn neurons are essential for integration of nociceptive input. Intrathecal injection of substance P-saporin (SP-SAP) leads to local loss of spinal NK1-r (+) neurons suggesting
Autor:
Philip J. Richter
Publikováno v:
Spiritus: A Journal of Christian Spirituality. 6:195-212
In the final years of his life Merton discovered a passion for photography. In Merton's hands the camera became a tool for natural contemplation. Strong critiques of the photographic gaze have since been developed, by Susan Sontag and others, dismiss
Autor:
Tony L. Yaksh, Harry Powell, Philip J. Richter, Robert R. Myers, Amy R. Bourdeau, Carl Lebel, Jean C. Dragani, Michael Rathbun, Shelle Malkmus
Publikováno v:
Toxicological Sciences. 38:89-100
To define the kinetics and safety of spinally infused recombinant-methionyl human brain-derived neurotrophic factor (r-metHuBDNF), beagle dogs were prepared with lumbar intrathecal catheters passed through the cisternal membrane to the L1-L4 lumbar l
Publikováno v:
Medical and Veterinary Entomology. 10:291-294
Autor:
Philip J. Richter, Richard M. Drake
Publikováno v:
Journal of Aerospace Engineering. 5:282-296
The paper examines and compares structural concepts considered for use as habitats for lunar and Martian outposts. An evaluation methodology that allows numeric rating of concepts was previously developed and is upgraded herein. The methodology defin
Autor:
Tony L. Yaksh, Philip J. Richter, Nikolai Bogduk, Anthony Dragovich, Steven P. Cohen, Connie Kurihara, Chester C. Buckenmaier, Jo Lynne Raymond, Scott R. Griffith, Necia Williams
Publikováno v:
Anesthesiology. 110(5)
Background Recent evidence implicates the inflammatory cytokine tumor necrosis factor as a major cause of radiculopathy. Yet, whereas open-label studies with systemically delivered tumor necrosis factor inhibitors have yielded positive results, a pla
Publikováno v:
Journal of Aerospace Engineering. 3:241-250
This paper summarizes the results of a qualitative investigation to identify concepts for design and construction of near-term lunar facilities. Accomplishing such construction will require an adaptation or transfer of current terrestrial technology