Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Philip J. Privitera"'
Publikováno v:
Cellular and Molecular Neurobiology. 23:805-815
1. The present study was undertaken to localize and characterize bradykinin (BK) binding sites in brains from Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). 2. Serial sections of brains were cut from adult WKY and SHR and specific [125
Autor:
Phillip W. Yates, Philip J. Privitera
Publikováno v:
Brain Research. 704:103-106
Microinjections of kallikrein, 0.5–2.0 units, in the rostral ventrolateral medulla (RVLM) of brain increased arterial pressure in Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). This effect was significantly greater in SHR. The kinin
Publikováno v:
Hypertension. 25:524-530
Abstract The objective of the present study was to determine whether the brain kallikrein-kinin system differs between spontaneously hypertensive rats (SHR) and normotensive Wistar-Kyoto rats (WKY) and if so, whether any detected differences occur be
Publikováno v:
Cellular and molecular neurobiology. 23(4-5)
1. The present study was undertaken to localize and characterize bradykinin (BK) binding sites in brains from Wistar-Kyoto (WKY) and spontaneously hypertensive rats (SHR). 2. Serial sections of brains were cut from adult WKY and SHR and specific [125
Autor:
Ayad A. Jaffa, Thomas A. Morinelli, Philip J. Privitera, G. Patrick Meier, Jerry G. Webb, Harry S. Margolius
Publikováno v:
International immunopharmacology. 2(13-14)
The peptide hormone bradykinin is a mediator in many physiological and pathological processes. The generation and, to a limited extent, metabolism occur at the sites of action. The short half-life of bradykinin (approximately 15 s) renders measuremen
Publikováno v:
Hypertension (Dallas, Tex. : 1979). 23(1)
In the present study, we focused on the rostral ventrolateral medulla as a possible site of action for kinins because of its established importance in the central regulation of the cardiovascular system. Unilateral microinjections of 100 pmol to 4 nm
Publikováno v:
Journal of hypertension. 11(10)
To determine whether immunoreactive tissue kallikrein levels in cerebrospinal fluid (CSF) of spontaneously hypertensive rats (SHR) and desoxycorticosterone acetate (DOCA)--salt-treated hypertensive rats are elevated compared with normotensive Wistar-
Publikováno v:
Brain research. 577(1)
The present study was undertaken to localize and characterize bradykinin (BK) binding sites in 10 microns serial sections of guinea pig brain by in vitro quantitative receptor autoradiography. Specific binding of [125I-Tyr8]bradykinin ([125I]BK) was
Publikováno v:
Hypertension. 4:634-641
SUMMARY While previous studies have shown that prostaglandins (PG) mediate the renal vasodilating and renin-releasing actions of furosemide, the dose-response relationship has not been defined nor has the specific PG involved. Prostacyclin (PGIj) is
Publikováno v:
Chirality. 1:192-196
Only limited information is available on the stereochemistry of the in vivo distribution of beta-receptor-blocking drugs. In this study we determined the levels of the propranolol enantiomers in plasma, cerebrospinal fluid (CSF) and central nervous s