Zobrazeno 1 - 10
of 241
pro vyhledávání: '"Philip J. Norris"'
Autor:
Erika G. Marques de Menezes, Scott A. Bowler, Cecilia M. Shikuma, Lishomwa C. Ndhlovu, Philip J. Norris
Publikováno v:
Frontiers in Neurology, Vol 15 (2024)
BackgroundAlthough effective antiretroviral therapy (ART) has improved the life expectancy of people with HIV (PWH), the prevalence of milder forms of HIV-associated neurocognitive disorders (HAND) persist, and it is associated with systemic and neur
Externí odkaz:
https://doaj.org/article/6de4734169194ec2ae940746b4ace112
Autor:
John F. McDyer, Mahzad Azimpouran, Valerie L. Durkalski-Mauldin, Robert G. Clevenger, Sharon D. Yeatts, Xutao Deng, William Barsan, Robert Silbergleit, Nahed El Kassar, Iulia Popescu, Dimiter Dimitrov, Wei Li, Emily J. Lyons, Sophia C. Lieber, Mars Stone, Frederick K. Korley, Clifton W. Callaway, Larry J. Dumont, Philip J. Norris, for the SIREN-C3PO Investigators
Publikováno v:
JCI Insight, Vol 8, Iss 8 (2023)
Multiple randomized, controlled clinical trials have yielded discordant results regarding the efficacy of convalescent plasma in outpatients, with some showing an approximately 2-fold reduction in risk and others showing no effect. We quantified bind
Externí odkaz:
https://doaj.org/article/7c19e4b03dd34452bc1b28ddfdf94cec
Autor:
Clara Di Germanio, Ernest L. Yufenyuy, Dylan C. Hampton, Chloe Thorbrogger, Bharat S. Parekh, Philip J. Norris
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 1 (2023)
ABSTRACT The HIV epidemic is still one of the world’s most serious public health challenges, affecting about 38 million people worldwide, especially in sub-Saharan African and Southeast Asian countries. In recent years, tests have been developed to
Externí odkaz:
https://doaj.org/article/a269bf9d3b7f4ecf886390dd1efb409a
Autor:
Erika G. Marques de Menezes, Jocelyn S. Liu, Scott A. Bowler, Leila B. Giron, Michelle L. D’Antoni, Cecilia M. Shikuma, Mohamed Abdel-Mohsen, Lishomwa C. Ndhlovu, Philip J. Norris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
BackgroundNeurocognitive impairment remains prevalent in people with HIV (PWH) despite long term virological suppression by antiretroviral therapy (ART) regimens. Systemic and neuro-inflammatory processes are suggested to contribute to the complex pa
Externí odkaz:
https://doaj.org/article/536e2f5815834ab88349d615c6ec14ca
Autor:
Paula Saá, Rebecca V. Fink, Sonia Bakkour, Jing Jin, Graham Simmons, Marcus O. Muench, Hina Dawar, Clara Di Germanio, Alvin J. Hui, David J. Wright, David E. Krysztof, Steven H. Kleinman, Angela Cheung, Theresa Nester, Debra A. Kessler, Rebecca L. Townsend, Bryan R. Spencer, Hany Kamel, Jacquelyn M. Vannoy, Honey Dave, Michael P. Busch, Susan L. Stramer, Mars Stone, Rachael P. Jackman, Philip J. Norris, for the NHLBI Recipient Epidemiology and Donor Evaluation Study-IV-Pediatric (REDS-IV-P)
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 17 (2022)
Respiratory viruses such as influenza do not typically cause viremia; however, SARS-CoV-2 has been detected in the blood of COVID-19 patients with mild and severe symptoms. Detection of SARS-CoV-2 in blood raises questions about its role in pathogene
Externí odkaz:
https://doaj.org/article/26f0766236b04ea0b20478828437491d
Autor:
Erika G. Marques de Menezes, Xutao Deng, Jocelyn Liu, Scott A. Bowler, Cecilia M. Shikuma, Mars Stone, Peter W. Hunt, Lishomwa C. Ndhlovu, Philip J. Norris
Publikováno v:
mBio, Vol 13, Iss 3 (2022)
ABSTRACT HIV-infected individuals have increased risk for cardiovascular disease (CVD) despite suppressive antiretroviral therapy (ART). This is likely a result of persistent immune activation and systemic inflammation. Extracellular vesicles (EVs) h
Externí odkaz:
https://doaj.org/article/18810f978900444f98045bcff62b240b
Autor:
Elizabeth E. McCarthy, Pamela M. Odorizzi, Emma Lutz, Carolyn P. Smullin, Iliana Tenvooren, Mars Stone, Graham Simmons, Peter W. Hunt, Margaret E. Feeney, Philip J. Norris, Michael P. Busch, Matthew H. Spitzer, Rachel L. Rutishauser
Publikováno v:
Cell Reports, Vol 39, Iss 7, Pp 110815- (2022)
Summary: Although generating high neutralizing antibody levels is a key component of protective immunity after acute viral infection or vaccination, little is known about why some individuals generate high versus low neutralizing antibody titers. Her
Externí odkaz:
https://doaj.org/article/cbc1018b4784449c874e910fbc107ece
Autor:
Hector Bonilla, Dylan Hampton, Erika G. Marques de Menezes, Xutao Deng, José G. Montoya, Jill Anderson, Philip J. Norris
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Myalgic encephalomyelitis, or chronic fatigue syndrome (ME/CFS) is a serious disease whose cause has yet to be identified. Objective markers of the disease are also not well understood and would serve as important tools in diagnosis and management. O
Externí odkaz:
https://doaj.org/article/dc675e6ad5854658ba3af48fd542e9cd
Autor:
Da Cheng, Zhenwu Luo, Xiaoyu Fu, Sophie Stephenson, Clara Di Germanio, Philip J. Norris, Dietmar Fuchs, Lishomwa C. Ndhlovu, Quan-zhen Li, Henrik Zetterberg, Magnus Gisslen, Richard W. Price, Shifang Peng, Wei Jiang
Publikováno v:
Microbiology Spectrum, Vol 10, Iss 1 (2022)
ABSTRACT The mechanisms of persistent central nervous system (CNS) inflammation in people with HIV (PWH) despite effective antiretroviral therapy (ART) are not fully understood. We have recently shown that plasma anti-CD4 IgGs contribute to poor CD4+
Externí odkaz:
https://doaj.org/article/5aae1f4d2d714f9db84cf5721ad8de34
Autor:
Rafael R. de Assis, Aarti Jain, Rie Nakajima, Algis Jasinskas, Jiin Felgner, Joshua M. Obiero, Philip J. Norris, Mars Stone, Graham Simmons, Anil Bagri, Johannes Irsch, Martin Schreiber, Andreas Buser, Andreas Holbro, Manuel Battegay, Philip Hosimer, Charles Noesen, Oluwasanmi Adenaiye, Sheldon Tai, Filbert Hong, Donald K. Milton, D. Huw Davies, Paul Contestable, Laurence M. Corash, Michael P. Busch, Philip L. Felgner, Saahir Khan
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
COVID-19 diagnosis is commonly performed by PCR testing, however, serologic methods are more accurate and versatile for monitoring disease burden and epidemiology. Here the authors report a protein microarray with antigens from SARS-CoV-2, SARS-CoV,
Externí odkaz:
https://doaj.org/article/307aa88ea3a740b187cbbb0355b0645c