Zobrazeno 1 - 10
of 165
pro vyhledávání: '"Philip J. Mason"'
Autor:
Koki Ueda, Kazuhiko Ikeda, Takayuki Ikezoe, Kayo Harada-Shirado, Kazuei Ogawa, Yuko Hashimoto, Takahiro Sano, Hiroshi Ohkawara, Satoshi Kimura, Akiko Shichishima-Nakamura, Yuichi Nakamura, Yayoi Shikama, Tsutomu Mori, Philip J. Mason, Monica Bessler, Soji Morishita, Norio Komatsu, Kotaro Shide, Kazuya Shimoda, Shuhei Koide, Kazumasa Aoyama, Motohiko Oshima, Atsushi Iwama, Yasuchika Takeishi
Publikováno v:
Blood Advances, Vol 1, Iss 15, Pp 1001-1015 (2017)
Abstract: High-mobility group AT-hook 2 (HMGA2) is crucial for the self-renewal of fetal hematopoietic stem cells (HSCs) but is downregulated in adult HSCs via repression by MIRlet-7 and the polycomb-recessive complex 2 (PRC2) including EZH2. The HMG
Externí odkaz:
https://doaj.org/article/7d35bd81e24048ababdc3f54d31b7553
Publikováno v:
Haematologica, Vol 92, Iss 8 (2007)
Externí odkaz:
https://doaj.org/article/6d3a50abd4074f6f83dc2ce2fd00fb34
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0152263 (2016)
MDM2, an E3 ubiquitin ligase, is an important negative regulator of tumor suppressor p53. In turn the Mdm2 gene is a transcriptional target of p53, forming a negative feedback loop that is important in cell cycle control. It has recently become appar
Externí odkaz:
https://doaj.org/article/2501cac069f4415ead36a7e3bd5a739e
Autor:
Esther N Pesciotta, Ho-Sun Lam, Andrew Kossenkov, Jingping Ge, Louise C Showe, Philip J Mason, Monica Bessler, David W Speicher
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0140036 (2015)
Diamond Blackfan Anemia (DBA) is a rare, congenital erythrocyte aplasia that is usually caused by haploinsufficiency of ribosomal proteins due to diverse mutations in one of several ribosomal genes. A striking feature of this disease is that a range
Externí odkaz:
https://doaj.org/article/1f0d042bd49c47488255dd5db71c7cb4
Autor:
Bai-Wei Gu, Marisa Apicella, Jason Mills, Jian-Meng Fan, Dara A Reeves, Deborah French, Gregory M Podsakoff, Monica Bessler, Philip J Mason
Publikováno v:
PLoS ONE, Vol 10, Iss 5, p e0127414 (2015)
Dyskeratosis congenita (DC) is an inherited bone marrow failure syndrome characterized by the presence of short telomeres at presentation. Mutations in ten different genes, whose products are involved in the telomere maintenance pathway, have been sh
Externí odkaz:
https://doaj.org/article/fa25a414ee30444c817c0548126284fa
Autor:
Jingping Ge, Marisa Apicella, Jason A Mills, Loïc Garçon, Deborah L French, Mitchell J Weiss, Monica Bessler, Philip J Mason
Publikováno v:
PLoS ONE, Vol 10, Iss 8, p e0134878 (2015)
Diamond Blackfan Anemia (DBA) is an inherited bone marrow failure syndrome with clinical features of red cell aplasia and variable developmental abnormalities. Most affected patients have heterozygous loss of function mutations in ribosomal protein g
Externí odkaz:
https://doaj.org/article/75d99552ab144d2ba76c4a5f76c95348
Autor:
Esther N Pesciotta, Sira Sriswasdi, Hsin-Yao Tang, David W Speicher, Philip J Mason, Monica Bessler
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e85504 (2014)
Diamond Blackfan Anemia (DBA) is a congenital anemia usually caused by diverse mutations in ribosomal proteins. Although the genetics of DBA are well characterized, the mechanisms that lead to macrocytic anemia remain unclear. We systematically analy
Externí odkaz:
https://doaj.org/article/2ef2562e0d4f448aa23ec05337d53a5a
Autor:
Yuichi Nakamura, Koki Ueda, Kazumasa Aoyama, Yuko Hashimoto, Atsushi Iwama, Kazuhiko Ikeda, Kotaro Shide, Takahiro Sano, Takayuki Ikezoe, Hiroshi Ohkawara, Monica Bessler, Tsutomu Mori, Satoshi Kimura, Yayoi Shikama, Philip J. Mason, Shuhei Koide, Motohiko Oshima, Kazuei Ogawa, Yasuchika Takeishi, Norio Komatsu, Soji Morishita, Kayo Harada-Shirado, Kazuya Shimoda, Akiko Shichishima-Nakamura
Publikováno v:
Blood Advances. 1:1001-1015
High-mobility group AT-hook 2 (HMGA2) is crucial for the self-renewal of fetal hematopoietic stem cells (HSCs) but is downregulated in adult HSCs via repression by MIRlet-7 and the polycomb-recessive complex 2 (PRC2) including EZH2. The HMGA2 messeng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0cc7431baba98df07d9406eefd654473
https://doi.org/10.1182/bloodadvances.2017004457
https://doi.org/10.1182/bloodadvances.2017004457
Autor:
Dimitri S. Monos, Anna Papazoglou, Gregory M. Podsakoff, Yimei Li, Marisol Betensky, Timothy S. Olson, Philip J Mason, Daria V. Babushok, Jaclyn A. Biegel, Monica Bessler, Tracy M. Busse, Jacquelyn J. Roth, Curt Lind
Publikováno v:
Cancer Genetics. 209:1-10
Acquired aplastic anemia (aAA) results from the T cell-mediated autoimmune destruction of hematopoietic stem cells. Factors predicting response to immune suppression therapy (IST) or development of myelodysplastic syndrome (MDS) are beginning to be e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c92d2b0e96e6dab1a83403b0d563a379
https://doi.org/10.1016/j.cancergen.2015.10.002
https://doi.org/10.1016/j.cancergen.2015.10.002
Autor:
M. D. Messier, T. E. Coan, Philip J. Mason, J. Cooper, C. R. Bower, M. Proudfoot, B. Baugh, L. Corwin, S. L. Mufson, Jonathan A. Karty, Anna Pla-Dalmau
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 799:1-9
The NOvA collaboration blended and delivered 8.8 kt (2.72M gal) of liquid scintillator as the active detector medium to its near and far detectors. The composition of this scintillator was specifically developed to satisfy NOvA׳s performance require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cbe7a9174df84ffda7d4a38f5450841
https://doi.org/10.1016/j.nima.2015.07.026
https://doi.org/10.1016/j.nima.2015.07.026