Comparative genomics of Burkholderia multivorans, a ubiquitous pathogen with a highly conserved genomic structure.

Autor: Charlotte Peeters, Vaughn S Cooper, Philip J Hatcher, Bart Verheyde, Aurélien Carlier, Peter Vandamme

Publikováno v: PLoS ONE, Vol 12, Iss 4, p e0176191 (2017)

The natural environment serves as a reservoir of opportunistic pathogens. A well-established method for studying the epidemiology of such opportunists is multilocus sequence typing, which in many cases has defined strains predisposed to causing infec

Externí odkaz: https://doaj.org/article/4deb1828077244ff9e92516de3a9d422

Core Genes Evolve Rapidly in the Long-Term Evolution Experiment with Escherichia coli

Autor: Debora S. Marks, Anna G. Green, Richard E. Lenski, Philip J. Hatcher, Barry L. Williams, Rohan Maddamsetti

Publikováno v: Genome Biology and Evolution

Bacteria can evolve rapidly under positive selection owing to their vast numbers, allowing their genes to diversify by adapting to different environments. We asked whether the same genes that evolve rapidly in the long-term evolution experiment (LTEE

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe6be2684a136af9a80ef5391ebda94
https://doi.org/10.1093/gbe/evx064

Benefit of transferred mutations is better predicted by the fitness of recipients than by their ecological or genetic relatedness

Autor: Marcus M. Dillon, Ethan Knapp, Carolina Díaz Arenas, Philip J. Hatcher, Daniel M. Stoebel, Kenneth M. Flynn, Vaughn S. Cooper, Francisco B.-G. Moore, Tim F. Cooper, Andrea Wünsche, Yinhua Wang

The effect of a mutation depends on its interaction with the genetic background in which it is assessed. Studies in experimental systems have demonstrated that such interactions are common among beneficial mutations and often follow a pattern consist

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::791f651ed348d76c301b39c4f4613feb
https://europepmc.org/articles/PMC4983819/

Evolutionary Rates and Gene Dispensability Associate with Replication Timing in the Archaeon Sulfolobus islandicus

Autor: Kenneth M. Flynn, Philip J. Hatcher, Vaughn S. Cooper, Samuel H. Vohr

Publikováno v: Genome Biology and Evolution

In bacterial chromosomes, the position of a gene relative to the single origin of replication generally reflects its replication timing, how often it is expressed, and consequently, its rate of evolution. However, because some archaeal genomes contai

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::145dab721f7e0d202aa222d6e1f8541c
https://doi.org/10.1093/gbe/evq068

Comparative genomics of Burkholderia multivorans, a ubiquitous pathogen with a highly conserved genomic structure

Autor: Aurélien Carlier, Vaughn S. Cooper, Peter Vandamme, Philip J. Hatcher, Bart Verheyde, Charlotte Peeters

Publikováno v: PLoS ONE
PLoS ONE, Vol 12, Iss 4, p e0176191 (2017)
PLoS ONE, Public Library of Science, 2017, 12 (4), pp.e0176191. ⟨10.1371/journal.pone.0176191⟩
PLOS ONE

The natural environment serves as a reservoir of opportunistic pathogens. A well-established method for studying the epidemiology of such opportunists is multilocus sequence typing, which in many cases has defined strains predisposed to causing infec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7320ffc1c724fb8273f60ad75faf7c1d
https://doi.org/10.1371/journal.pone.0176191