Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Philip J. Goddard"'
Autor:
Richard Fitzpatrick, E. Pat Cannon, Pamela Kelly, Alex Brezzani, Andrew T. Papoulis, Philip J. Goddard, Jeffrey D. Klinger, Emilie Rinard, Robert H. Barker, David W. K. Acheson, Mary Pitruzzello, Carol Dinardo, Keith K. Shackett, Caroline B. Kurtz, Gerard P. Palace
Publikováno v:
Antimicrobial Agents and Chemotherapy. 45:2340-2347
GT160-246, a high-molecular-weight soluble anionic polymer, was tested in vitro and in vivo for neutralization of Clostridium difficile toxin A and B activities. Five milligrams of GT160-246 per ml neutralized toxin-mediated inhibition of protein syn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d163567891b289e4b94152f0e2c983c4
https://doi.org/10.1128/aac.45.8.2340-2347.2001
https://doi.org/10.1128/aac.45.8.2340-2347.2001
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 76:882-890
HCO3- secretion across in vitro duodenal mucosa of Rana catesbeiana was investigated under baseline conditions and during secretory stimulation. Baseline secretion was abolished by removal of CO2-HCO3- and reduced - 60% by removal of nutrient Na+, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::49b39b720926f2047c3ede74e6d00a19
https://doi.org/10.1139/y98-095
https://doi.org/10.1139/y98-095
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 76:882-890
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9190cc5aa6520f307a938792d0189af0
https://doi.org/10.1139/cjpp-76-9-882
https://doi.org/10.1139/cjpp-76-9-882
Autor:
Susumo Ito, William Silen, K. J. Carter, Hannu Paimela, Robert Khakee, Paul L. McNeil, Philip J. Goddard
Publikováno v:
Gastroenterology. 104:1337-1345
Background: Rapid re-epithelialization after superficial gastric mucosal injury is caused by migration of persisting viable epithelial cells. Basic fibroblast growth factor (bFGF) has been reported to enhance the healing of experimental duodenal ulce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165cd95274442a3487b5d862a5bec7d0
https://doi.org/10.1016/0016-5085(93)90342-a
https://doi.org/10.1016/0016-5085(93)90342-a
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 261:G781-G789
The effect of intracellular acidosis on luminal H+ secretion and the role of H(+)-K(+)-ATPase in regulation of intracellular pH (pHi) in oxynticopeptic cells (OPC) (measured with a pH-sensitive fluorescent dye) were examined in intact sheets of in vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4f6eaa2b497d1df2de471d876f82c1
https://doi.org/10.1152/ajpgi.1991.261.5.g781
https://doi.org/10.1152/ajpgi.1991.261.5.g781
Publikováno v:
Gastroenterology. 98:592-606
An iodoplatinate technique that selectively stains phospholipid was used to evaluate morphologically the effects of aspirin and 16,16-dimethyl prostaglandin E2 on canine gastric mucosa in an in vitro Ussing chamber system. The association between the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0e9ec2c7fc28dbe09302ed1ecf2cb0ce
https://doi.org/10.1016/0016-5085(90)90278-9
https://doi.org/10.1016/0016-5085(90)90278-9
Publikováno v:
Gastroenterology. 98:361-370
The contribution of the surface mucous gel to the stomach's hydrophobic luminal properties and how these properties are affected by both damaging and cytoprotective agents were studied. Canine gastric mucosa, determined to be hydrophobic in nature by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61b8b38c86395656e2ff24925818d06e
https://doi.org/10.1016/0016-5085(90)90826-m
https://doi.org/10.1016/0016-5085(90)90826-m
Publikováno v:
Digestive diseases and sciences. 40(11)
reviewed by Silen (15) and Lacy (16). A brief luminal exposure to hypertonic saline was used to induce superficial injury to oxyntic mucosa. Morphologically evident reepithelialization occurred concurrently with the return of mucosal electrophysiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d8d7b77b0cd54528473625aa7de3ab
https://pubmed.ncbi.nlm.nih.gov/7587840
https://pubmed.ncbi.nlm.nih.gov/7587840
Publikováno v:
Digestive diseases and sciences. 40(6)
This study determined how the luminal surface hydrophobicity and transmucosal potential difference (PD) of canine gastric mucosa changed during the recovery period after the tissue was challenged with acidified aspirin. Luminal aspirin reduced both t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53ab4c2195b9b4465c7bb306cd1f643d
https://pubmed.ncbi.nlm.nih.gov/7781460
https://pubmed.ncbi.nlm.nih.gov/7781460
Publikováno v:
The American journal of physiology. 262(1 Pt 1)
Prostaglandins, shown to stimulate Cl- transport in epithelial cells of several different tissues, protect gastric mucosa against physiological injury induced by luminal acid. To clarify the relationship between the stimulation of Cl(-)-transport and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3af2c21940ee7200b0b825515b997c3d
https://pubmed.ncbi.nlm.nih.gov/1733269
https://pubmed.ncbi.nlm.nih.gov/1733269