Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Philip J. Drew"'
Autor:
Laura Smith, Omar Qutob, Mark B. Watson, Andrew W. Beavis, Donna Potts, Kevin J. Welham, Veerabhadram Garimella, Michael J. Lind, Philip J. Drew, Lynn Cawkwell
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 11, Pp 1194-1207 (2009)
PURPOSE: We aimed to identify putative predictive protein biomarkers of radioresistance. EXPERIMENTAL DESIGN: Three breast cancer cell lines (MCF7, MDA-MB-231, and T47D) were used as in vitro models to study radioresistance. Inherent radiosensitiviti
Externí odkaz:
https://doaj.org/article/2db5ab3997264950808d2c40c380f002
Publikováno v:
European Journal of Surgical Oncology. 46:e57
Publikováno v:
European Journal of Surgical Oncology. 44:915-916
Autor:
Penelope McManus, Tapan Mahapatra, Dalia ELFadl, Philip J. Drew, Vijay Agarwal, P.J. Kneeshaw, Victoria C. Hodgkinson, John N. Fox, Michael J. Lind, Lynn Cawkwell
Publikováno v:
Journal of Proteomics. 75:2745-2752
Neoadjuvant chemotherapy is used to treat oestrogen receptor-positive breast cancer however chemo-resistance is a major obstacle in this molecular subtype. The ability to predict tumour response would allow chemotherapy administration to be directed
Autor:
P.J. Kneeshaw, Tapan Mahapatra, Dalia ELFadl, Ervine D. Long, Penelope McManus, Michael J. Lind, John N. Fox, V. Garimella, Philip J. Drew, Vijay Agarwal, Charlotte Russell, Lynn Cawkwell, Victoria C. Hodgkinson
Publikováno v:
Journal of Proteomics. 75:1276-1283
Introduction Chemotherapy resistance is a major obstacle in effective neoadjuvant treatment for estrogen receptor-positive breast cancer. The ability to predict tumour response would allow chemotherapy administration to be directed towards only those
Autor:
Lynn Cawkwell, Michael J. Lind, Philip J. Drew, V.C. Hodgkinson, V Garimella, D ELFadl, V Agarwal
Publikováno v:
Cancer Research. 71:P5-13
Background: Chemotherapy resistance is a major obstacle in effective neoadjuvant treatment for oestrogen receptor (ER)-positive breast cancer. The ability to predict tumour response would allow chemotherapy administration to be directed towards only
Publikováno v:
Expert Review of Proteomics. 8:535-552
The individualization of radiotherapy treatment would be beneficial for cancer patients; however, there are no predictive biomarkers of radiotherapy resistance in routine clinical use. This article describes the body of work in this field where compa
Autor:
Victoria C. Hodgkinson, Ervine D. Long, Lynn Cawkwell, Lucy Scaife, Michael J. Lind, Dalia ELFadl, Philip J. Drew
Publikováno v:
The Breast. 20:334-337
Breast conserving therapy is a currently accepted method for managing patients with early stage breast cancer. However, approximately 7% of patients may develop loco-regional tumour recurrence within 5 years. We previously reported that expression of
Autor:
Penelope McManus, Tapan Mahapatra, V. S.R. Rao, John N. Fox, Jainudeen K.A. Jameel, Philip J. Drew
Publikováno v:
The Breast Journal. 13:368-373
As breast cancer is the most frequent cancer in the elderly with a peak incidence of 1 in 10 by the age of 80, it is important to establish optimum therapy in this group. We conducted a case note-based retrospective study of all elderly primary breas
Autor:
Lindsay W. Turnbull, John N. Fox, Ervine D. Long, V. Garimella, A. Chaturvedi, O. Qutob, Philip J. Drew
Publikováno v:
European Journal of Surgical Oncology (EJSO). 33:157-161
Background Neoadjuvant therapy results in a significant increase in breast-conserving surgery. However, traditional imaging methods are unable to accurately predict the extent of viable residual disease leading to uncertainty in surgical planning and