Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Philip J. Dittmer"'
Publikováno v:
Cell Reports, Vol 19, Iss 2, Pp 321-334 (2017)
Summary: Potentiation of synaptic strength relies on postsynaptic Ca2+ signals, modification of dendritic spine structure, and changes in gene expression. One Ca2+ signaling pathway supporting these processes routes through L-type Ca2+ channels (LTCC
Externí odkaz:
https://doaj.org/article/96f0152f32fc42d2830f557d040799ba
Autor:
Angela R. Wild, Brooke L. Sinnen, Philip J. Dittmer, Matthew J. Kennedy, William A. Sather, Mark L. Dell’Acqua
Publikováno v:
Cell Reports, Vol 26, Iss 13, Pp 3537-3550.e4 (2019)
Summary: Long-term information storage in the brain requires continual modification of the neuronal transcriptome. Synaptic inputs located hundreds of micrometers from the nucleus can regulate gene transcription, requiring high-fidelity, long-range s
Externí odkaz:
https://doaj.org/article/6ce51fc0392c409f9aedb860a58b1965
Publikováno v:
Cell Reports, Vol 7, Iss 5, Pp 1410-1416 (2014)
Within neurons, Ca2+-dependent inactivation (CDI) of voltage-gated L-type Ca2+ channels shapes cytoplasmic Ca2+ signals. CDI is initiated by Ca2+ binding to channel-associated calmodulin and subsequent Ca2+/calmodulin activation of the Ca2+-dependent
Externí odkaz:
https://doaj.org/article/d26b4a4f73354477ac3f6f601d47566c
Autor:
Mark L. Dell'Acqua, Jonathan G. Murphy, William A. Sather, Kevin C. Crosby, Philip J. Dittmer
Publikováno v:
Molecular Biology of the Cell. 30:1743-1756
In neurons, regulation of activity-dependent transcription by the nuclear factor of activated T-cells (NFAT) depends upon Ca2+influx through voltage-gated L-type calcium channels (LTCC) and NFAT translocation to the nucleus following its dephosphoryl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6fe94fa58c4becb763045fcc8267720a
https://doi.org/10.1091/mbc.e19-01-0060
https://doi.org/10.1091/mbc.e19-01-0060
Publikováno v:
Proceedings of the National Academy of Sciences. 116:13611-13620
Patterns of postsynaptic activity that induce long-term potentiation of fast excitatory transmission at glutamatergic synapses between hippocampal neurons cause enlargement of the dendritic spine and promote growth in spine endoplasmic reticulum (ER)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05e24b34c989b87a9c360b53b256a46c
https://doi.org/10.1073/pnas.1902461116
https://doi.org/10.1073/pnas.1902461116
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America. 116(27)
Patterns of postsynaptic activity that induce long-term potentiation of fast excitatory transmission at glutamatergic synapses between hippocampal neurons cause enlargement of the dendritic spine and promote growth in spine endoplasmic reticulum (ER)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::18202659aaebb5cde30499f345107c18
https://pubmed.ncbi.nlm.nih.gov/31209051
https://pubmed.ncbi.nlm.nih.gov/31209051
Autor:
Jonathan G, Murphy, Kevin C, Crosby, Philip J, Dittmer, William A, Sather, Mark L, Dell'Acqua
Publikováno v:
Molecular Biology of the Cell
In neurons, regulation of activity-dependent transcription by the nuclear factor of activated T-cells (NFAT) depends upon Ca2+ influx through voltage-gated L-type calcium channels (LTCC) and NFAT translocation to the nucleus following its dephosphory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5b039a8341de544403f0d33d3b046832
https://pubmed.ncbi.nlm.nih.gov/31091162
https://pubmed.ncbi.nlm.nih.gov/31091162
Autor:
Angela R, Wild, Brooke L, Sinnen, Philip J, Dittmer, Matthew J, Kennedy, William A, Sather, Mark L, Dell'Acqua
Publikováno v:
Cell reports
SUMMARY Long-term information storage in the brain requires continual modification of the neuronal transcriptome. Synaptic inputs located hundreds of micrometers from the nucleus can regulate gene transcription, requiring high-fidelity, long-range si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2324d0fa5b3123bebd2f65d7e0cdabbb
https://pubmed.ncbi.nlm.nih.gov/30917310
https://pubmed.ncbi.nlm.nih.gov/30917310
Autor:
Alexander, Polster, Philip J, Dittmer, Stefano, Perni, Hicham, Bichraoui, William A, Sather, Kurt G, Beam
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 38(43)
Stac protein (named for its SH3- and cysteine-rich domains) was first identified in brain 20 years ago and is currently known to have three isoforms. Stac2, Stac1, and Stac3 transcripts are found at high, modest, and very low levels, respectively, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::96f238d503eea378c7ceac2c2681366e
https://pubmed.ncbi.nlm.nih.gov/30201773
https://pubmed.ncbi.nlm.nih.gov/30201773
Publikováno v:
Biophysical Journal. 114:286a-287a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab05eff94e717ca1f3c0ca4eb6e647a4
https://doi.org/10.1016/j.bpj.2017.11.1643
https://doi.org/10.1016/j.bpj.2017.11.1643