Zobrazeno 1 - 10
of 257
pro vyhledávání: '"Philip J Thompson"'
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e87175 (2014)
The kinin B₁ receptor (B₁R) is rapidly upregulated after tissue trauma or inflammation and is involved in cancer and inflammatory diseases such as asthma. However, the role of the: promoter; a postulated alternative promoter; and spliced variants
Externí odkaz:
https://doaj.org/article/1cfdd25b2eb94828bcacfb1f955a475d
Autor:
Li Ping Chung, Svetlana Baltic, Manuel Ferreira, Suzanna Temple, Grant Waterer, Philip J Thompson
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e93695 (2014)
BACKGROUND: β2 adrenergic receptor (ADRβ2) polymorphisms including ADRβ2+46G>A have been reported to cause adverse outcomes in mild asthmatics. The extent to which ADRβ2 polymorphisms and in particular their haplotypes contribute to severe asthma
Externí odkaz:
https://doaj.org/article/d97e0a8ec7544e8994c9f5f93c4d8e6a
Autor:
Adaikalavan Ramasamy, Mikko Kuokkanen, Sailaja Vedantam, Zofia K Gajdos, Alexessander Couto Alves, Helen N Lyon, Manuel A R Ferreira, David P Strachan, Jing Hua Zhao, Michael J Abramson, Matthew A Brown, Lachlan Coin, Shyamali C Dharmage, David L Duffy, Tari Haahtela, Andrew C Heath, Christer Janson, Mika Kähönen, Kay-Tee Khaw, Jaana Laitinen, Peter Le Souef, Terho Lehtimäki, Australian Asthma Genetics Consortium collaborators, Pamela A F Madden, Guy B Marks, Nicholas G Martin, Melanie C Matheson, Cameron D Palmer, Aarno Palotie, Anneli Pouta, Colin F Robertson, Jorma Viikari, Elisabeth Widen, Matthias Wjst, Deborah L Jarvis, Grant W Montgomery, Philip J Thompson, Nick Wareham, Johan Eriksson, Pekka Jousilahti, Tarja Laitinen, Juha Pekkanen, Olli T Raitakari, George T O'Connor, Veikko Salomaa, Marjo-Riitta Jarvelin, Joel N Hirschhorn
Publikováno v:
PLoS ONE, Vol 8, Iss 3 (2013)
[This corrects the article DOI: 10.1371/journal.pone.0044008.].
Externí odkaz:
https://doaj.org/article/731bc0c9a5f74d86b5e0ca5199bfcf97
Autor:
Chuan Bian Lim, Cecilia M Prêle, Hui Min Cheah, Yuen Yee Cheng, Sonja Klebe, Glen Reid, D Neil Watkins, Svetlana Baltic, Philip J Thompson, Steven E Mutsaers
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66685 (2013)
BACKGROUND: The Hedgehog (HH) signaling pathway is critical for embryonic development and adult homeostasis. Recent studies have identified regulatory roles for this pathway in certain cancers with mutations in the HH pathway genes. The extent to whi
Externí odkaz:
https://doaj.org/article/8fb1acf1b01742ddb64b80e1669bc29c
Autor:
Adaikalavan Ramasamy, Mikko Kuokkanen, Sailaja Vedantam, Zofia K Gajdos, Alexessander Couto Alves, Helen N Lyon, Manuel A R Ferreira, David P Strachan, Jing Hua Zhao, Michael J Abramson, Matthew A Brown, Lachlan Coin, Shyamali C Dharmage, David L Duffy, Tari Haahtela, Andrew C Heath, Christer Janson, Mika Kähönen, Kay-Tee Khaw, Jaana Laitinen, Peter Le Souef, Terho Lehtimäki, Australian Asthma Genetics Consortium Collaborators, Pamela A F Madden, Guy B Marks, Nicholas G Martin, Melanie C Matheson, Cameron D Palmer, Aarno Palotie, Anneli Pouta, Colin F Robertson, Jorma Viikari, Elisabeth Widen, Matthias Wjst, Deborah L Jarvis, Grant W Montgomery, Philip J Thompson, Nick Wareham, Johan Eriksson, Pekka Jousilahti, Tarja Laitinen, Juha Pekkanen, Olli T Raitakari, George T O'Connor, Veikko Salomaa, Marjo-Riitta Jarvelin, Joel N Hirschhorn
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e44008 (2012)
Asthma has substantial morbidity and mortality and a strong genetic component, but identification of genetic risk factors is limited by availability of suitable studies.To test if population-based cohorts with self-reported physician-diagnosed asthma
Externí odkaz:
https://doaj.org/article/c816652d63b14f159aa85ccbfad1b788
Autor:
Unnur S Bjornsdottir, Stephen T Holgate, Padmalatha S Reddy, Andrew A Hill, Charlotte M McKee, Cristina I Csimma, Amy A Weaver, Holly M Legault, Clayton G Small, Renee C Ramsey, Debra K Ellis, Conor M Burke, Philip J Thompson, Peter H Howarth, Andrew J Wardlaw, Phillip G Bardin, David I Bernstein, Louis B Irving, Geoffrey L Chupp, George W Bensch, Gregory W Bensch, Jon E Stahlman, Monroe Karetzky, James W Baker, Rachel L Miller, Brad H Goodman, Donald G Raible, Samuel J Goldman, Douglas K Miller, John L Ryan, Andrew J Dorner, Frederick W Immermann, Margot O'Toole
Publikováno v:
PLoS ONE, Vol 6, Iss 7, p e21902 (2011)
Asthma exacerbations remain a major unmet clinical need. The difficulty in obtaining airway tissue and bronchoalveolar lavage samples during exacerbations has greatly hampered study of naturally occurring exacerbations. This study was conducted to de
Externí odkaz:
https://doaj.org/article/f4ed057e1067408a9023f1d201f1a2b4
Autor:
Cecilia M. Prêle, Thomas Iosifidis, Robin J. McAnulty, David R. Pearce, Bahareh Badrian, Tylah Miles, Sarra E. Jamieson, Matthias Ernst, Philip J. Thompson, Geoffrey J. Laurent, Darryl A. Knight, Steven E. Mutsaers
Publikováno v:
Biomedicines, Vol 9, Iss 5, p 498 (2021)
The interleukin (IL)-6 family of cytokines and exaggerated signal transducer and activator of transcription (STAT)3 signaling is implicated in idiopathic pulmonary fibrosis (IPF) pathogenesis, but the mechanisms regulating STAT3 expression and functi
Externí odkaz:
https://doaj.org/article/f48fa198e8004c7484e59b7e0c37a1fd
Autor:
Kerry L Hancock, Sinthia Bosnic-Anticevich, John D Blakey, Mark Hew, Li Ping Chung, Biljana Cvetkovski, Scott Claxton, Peter Del Fante, Eve Denton, Joe Doan, Kanchanamala Ranasinghe, Lucy Morgan, Anita Sharma, Peter K Smith, Deb Stewart, Philip J Thompson, Russell Wiseman, John W Upham, Kwok Y Yan, Victoria Carter, Kiranjeet Dhillon, Florian Heraud, Thao Le, Rebecca Vella, David Price
Publikováno v:
Pragmatic and Observational Research.
Kerry L Hancock,1 Sinthia Bosnic-Anticevich,2â 4 John D Blakey,5,6 Mark Hew,7,8 Li Ping Chung,9 Biljana Cvetkovski,3 Scott Claxton,10 Peter Del Fante,11 Eve Denton,7,8 Joe Doan,12 Kanchanamala Ranasinghe,13,14 Lucy Morgan,15â 17 Anita Sharm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47fd204d7ca763a874721335eb948c07
https://www.dovepress.com/characterisation-of-the-australian-adult-population-living-with-asthma-peer-reviewed-fulltext-article-POR
https://www.dovepress.com/characterisation-of-the-australian-adult-population-living-with-asthma-peer-reviewed-fulltext-article-POR
Autor:
Philip J. Thompson, Gerard J. Criner, Mark T. Dransfield, David M. G. Halpin, MeiLan K. Han, David A. Lipson, Ghassan J. Maghzal, Fernando J. Martinez, Dawn Midwinter, Dave Singh, Lee Tombs, Robert A. Wise
Publikováno v:
Respirology (Carlton, Vic.)REFERENCES. 27(12)
Chronic mucus hypersecretion (CMH) is a clinical phenotype of COPD. This exploratory post hoc analysis assessed relationship between CMH status and treatment response in IMPACT.Patients were randomized to once-daily fluticasone furoate/umeclidinium/v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37b148640eb928e46773c35177512fca
https://pubmed.ncbi.nlm.nih.gov/36031687
https://pubmed.ncbi.nlm.nih.gov/36031687
Autor:
Philip J. Thompson
Publikováno v:
Respirology. 25:7-10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb857fc974922842b2327b5f25a74a2
https://doi.org/10.1111/resp.13731
https://doi.org/10.1111/resp.13731