Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Philip J Shaw"'
Autor:
Philip J Shaw, Pavita Kaewprommal, Chayaphat Wongsombat, Chumpol Ngampiw, Tana Taechalertpaisarn, Sumalee Kamchonwongpaisan, Sissades Tongsima, Jittima Piriyapongsa
Publikováno v:
PLoS ONE, Vol 17, Iss 11, p e0276956 (2022)
The Plasmodium falciparum human malaria parasite genome is incompletely annotated and does not accurately represent the transcriptomic diversity of this species. To address this need, we performed long-read transcriptomic sequencing. 5' capped mRNA w
Externí odkaz:
https://doaj.org/article/43720a9730ac4faf8e4fbacb580c9ec5
Autor:
Yuttachon Promworn, Pavita Kaewprommal, Philip J Shaw, Apichart Intarapanich, Sissades Tongsima, Jittima Piriyapongsa
Publikováno v:
PLoS ONE, Vol 12, Iss 5, p e0178483 (2017)
Biochemical methods are available for enriching 5' ends of RNAs in prokaryotes, which are employed in the differential RNA-seq (dRNA-seq) and the more recent Cappable-seq protocols. Computational methods are needed to locate RNA 5' ends from these da
Externí odkaz:
https://doaj.org/article/0d7bc2460eaf4775996f7f8b27cc959f
Autor:
Brad E Sleebs, Sash Lopaticki, Danushka S Marapana, Matthew T O'Neill, Pravin Rajasekaran, Michelle Gazdik, Svenja Günther, Lachlan W Whitehead, Kym N Lowes, Lea Barfod, Lars Hviid, Philip J Shaw, Anthony N Hodder, Brian J Smith, Alan F Cowman, Justin A Boddey
Publikováno v:
PLoS Biology, Vol 12, Iss 7, p e1001897 (2014)
The malaria parasite Plasmodium falciparum exports several hundred proteins into the infected erythrocyte that are involved in cellular remodeling and severe virulence. The export mechanism involves the Plasmodium export element (PEXEL), which is a c
Externí odkaz:
https://doaj.org/article/577c998d81b343c095e557df66f4d3e1
Autor:
Parichat Prommana, Chairat Uthaipibull, Chayaphat Wongsombat, Sumalee Kamchonwongpaisan, Yongyuth Yuthavong, Ellen Knuepfer, Anthony A Holder, Philip J Shaw
Publikováno v:
PLoS ONE, Vol 8, Iss 8, p e73783 (2013)
Conventional reverse genetic approaches for study of Plasmodium malaria parasite gene function are limited, or not applicable. Hence, new inducible systems are needed. Here we describe a method to control P. falciparum gene expression in which target
Externí odkaz:
https://doaj.org/article/cbdb79dbc4e3405a975346b77b49e550
Autor:
Chumpol Ngamphiw, Anunchai Assawamakin, Shuhua Xu, Philip J Shaw, Jin Ok Yang, Ho Ghang, Jong Bhak, Edison Liu, Sissades Tongsima, HUGO Pan-Asian SNP Consortium
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e21451 (2011)
The HUGO Pan-Asian SNP consortium conducted the largest survey to date of human genetic diversity among Asians by sampling 1,719 unrelated individuals among 71 populations from China, India, Indonesia, Japan, Malaysia, the Philippines, Singapore, Sou
Externí odkaz:
https://doaj.org/article/9955a50216c94c52bafa54db40618b1e
Autor:
Nirut Leela, Parichat Prommana, Sumalee Kamchonwongpaisan, Tana Taechalertpaisarn, Philip J. Shaw
Publikováno v:
PeerJ, Vol 12, p e16595 (2024)
Background Plasmodium falciparum possesses a cobalamin-dependent methionine synthase (MS). MS is putatively encoded by the PF3D7_1233700 gene, which is orthologous and syntenic in Plasmodium. However, its vulnerability as an antimalarial target has n
Externí odkaz:
https://doaj.org/article/461d655f64c342c892bb3663b3f503ee
Autor:
Tanyaluck Kampoun, Somdet Srichairatanakool, Parichat Prommana, Philip J. Shaw, Judith L. Green, Ellen Knuepfer, Anthony A. Holder, Chairat Uthaipibull
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-10 (2022)
Abstract Background The resistance of Plasmodium falciparum to artemisinin-based (ART) drugs, the front-line drug family used in artemisinin-based combination therapy (ACT) for treatment of malaria, is of great concern. Mutations in the kelch13 (k13)
Externí odkaz:
https://doaj.org/article/3196b35f1366420a955e8f0b0687d746
Autor:
Tanyaluck Kampoun, Pimpisid Koonyosying, Jetsada Ruangsuriya, Parichat Prommana, Philip J. Shaw, Sumalee Kamchonwongpaisan, Hery Suwito, Ni Nyoman Tri Puspaningsih, Chairat Uthaipibull, Somdet Srichairatanakool
Publikováno v:
PeerJ, Vol 11, p e15187 (2023)
Background The spread of artemisinin (ART)-resistant Plasmodium falciparum threatens the control of malaria. Mutations in the propeller domains of P. falciparum Kelch13 (k13) are strongly associated with ART resistance. Ferredoxin (Fd), a component o
Externí odkaz:
https://doaj.org/article/9ddd048ae9cc4271866b143b21b28003
Autor:
Aiyada Aroonsri, Navaporn Posayapisit, Jindaporn Kongsee, Onsiri Siripan, Danoo Vitsupakorn, Sugunya Utaida, Chairat Uthaipibull, Sumalee Kamchonwongpaisan, Philip J. Shaw
Publikováno v:
PeerJ, Vol 7, p e6713 (2019)
Background Hypusination is an essential post-translational modification in eukaryotes. The two enzymes required for this modification, namely deoxyhypusine synthase (DHS) and deoxyhypusine hydrolase are also conserved. Plasmodium falciparum human mal
Externí odkaz:
https://doaj.org/article/ca6d8441e3c94a5b88eac9502cbab83d
Autor:
Jittima Piriyapongsa, Pavita Kaewprommal, Sirintra Vaiwsri, Songtham Anuntakarun, Warodom Wirojsirasak, Prapat Punpee, Peeraya Klomsa-ard, Philip J. Shaw, Wirulda Pootakham, Thippawan Yoocha, Duangjai Sangsrakru, Sithichoke Tangphatsornruang, Sissades Tongsima, Somvong Tragoonrung
Publikováno v:
PeerJ, Vol 6, p e5818 (2018)
Background Sugarcane is an important global food crop and energy resource. To facilitate the sugarcane improvement program, genome and gene information are important for studying traits at the molecular level. Most currently available transcriptome d
Externí odkaz:
https://doaj.org/article/7cfd1cda55944370ac120e0187371638